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1.发明公开Synthetic plasmid, transformant, feline interferon gene and method for producing feline interferon 失效合成的质粒，转化的细胞，猫干扰素基因和用于生产猫干扰素的方法。
公开(公告)号：EP0322870A2
公开(公告)日：1989-07-05
申请号：EP88121737.6
申请日：1988-12-27
发明人： Yanai, Akira , Nakamura, Naoko , Matsuda, Susumu
CPC分类号： C07K14/555
摘要： A synthetic plasmid in which DNA encoding protein of a feline interferon is integrated, a transformant obtainable by the transformation of a host cell by the use of the synthetic plasmid and a feline interferon having a biological activity given by a protein carrying a specific amino acid sequence, a feline interferon gene encoding the feline interferon, a feline interferon precursor comprised of a cleavable peptide or a signal peptide being linked to the N terminal of the feline interferon, a feline interferon precursor gene encoding the feline interferon precursor and a method for producing the feline interferon, which are applied to the mass production of a feline interferon to be used as a remedy for feline viral disease and tumor.
摘要翻译： 在猫干扰素的哪种编码DNA的蛋白A合成的质粒是集成的，转化体可获得的由宿主细胞的转化通过使用合成的质粒，并具有通过进行特定的氨基酸序列的蛋白质赋予生物活性的猫干扰素 中，编码猫干扰素猫干扰素基因，包含可切割的肽或信号肽的猫干扰素的前体被连接到猫干扰素，编码猫干扰素的前体及其制造方法的猫干扰素前体基因的N末端 猫干扰素，被施加到大量生产的猫干扰素的被用作猫科动物病毒疾病和肿瘤的药物。
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2.发明公开Feline interferon and process for production thereof by a silkworm virus vector 失效Katzeninteferon und Verfahren zur Herstellung mittels eines Seidenraupenvirus als Vektor。
公开(公告)号：EP0414355A1
公开(公告)日：1991-02-27
申请号：EP90307159.5
申请日：1990-06-29
发明人： Yanai, Akira , Ueda, Yoshizumi , Sakurai, Toru , Satoh, Masahiro
CPC分类号： C12N15/86 , C07K14/555 , C12N2710/14143
摘要： A recombinant silkworm nuclear polyhedrosis virus containing DNA coding for a protein of feline interferon; the recombinant virus is constructed by cotransfection a recombinant plasmid having a gene coding for a protein of feline interferon and a silkworm nuclear polyhedrosis virus DNA into established silkworm cells, and cloning the desired recombinant virus. The recombinant virus is useful for a mass-production of feline interferon.
摘要翻译： 含有编码猫干扰素蛋白质的DNA的重组蚕核型多角体病毒; 通过将具有编码猫干扰素和蚕核多角体病毒DNA的蛋白质的基因的重组质粒共转染到建立的蚕细胞中，并克隆所需的重组病毒构建重组病毒。 重组病毒可用于大量生产猫干扰素。
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3.发明授权Feline interferon and process for production thereof by a silkworm virus vector 失效猫干扰素和方法用于制备由蚕病毒的手段作为载体
公开(公告)号：EP0414355B1
公开(公告)日：2000-04-26
申请号：EP90307159.5
申请日：1990-06-29
发明人： Yanai, Akira , Ueda, Yoshizumi , Sakurai, Toru , Satoh, Masahiro
IPC分类号： C12N15/86 , C07K14/555
CPC分类号： C12N15/86 , C07K14/555 , C12N2710/14143
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公开(公告)号：EP0219808B1
公开(公告)日：1993-12-22
申请号：EP86114285.9
申请日：1986-10-15
发明人： Yanai, Akira , Ueda, Yoshizumi
IPC分类号： C12N15/74
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5.发明公开Synthetic plasmid, transformant, feline interferon gene and method for producing feline interferon 失效合成树脂，变性剂，菲律宾干扰素基因及生产FELINE INTERFERON的方法
公开(公告)号：EP0322870A3
公开(公告)日：1990-05-09
申请号：EP88121737.6
申请日：1988-12-27
发明人： Yanai, Akira , Nakamura, Naoko , Matsuda, Susumu
CPC分类号： C07K14/555
摘要： A synthetic plasmid in which DNA encoding protein of a feline interferon is integrated, a transformant obtainable by the transformation of a host cell by the use of the synthetic plasmid and a feline interferon having a biological activity given by a protein carrying a specific amino acid sequence, a feline interferon gene encoding the feline interferon, a feline interferon precursor comprised of a cleavable peptide or a signal peptide being linked to the N terminal of the feline interferon, a feline interferon precursor gene encoding the feline interferon precursor and a method for producing the feline interferon, which are applied to the mass production of a feline interferon to be used as a remedy for feline viral disease and tumor.
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6.发明授权Synthetic plasmid, transformant, feline interferon gene and method for producing feline interferon 失效合成的质粒，转化的细胞，猫干扰素基因和用于生产猫干扰素的方法。
公开(公告)号：EP0322870B1
公开(公告)日：1995-04-05
申请号：EP88121737.6
申请日：1988-12-27
发明人： Yanai, Akira , Nakamura, Naoko , Matsuda, Susumu
CPC分类号： C07K14/555
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7.发明公开Plasmid with wide host range and process of producing L-threonine using the same 失效具有宽主机范围的等离子体和使用其生产L-噻吩的方法
公开(公告)号：EP0219808A3
公开(公告)日：1988-12-28
申请号：EP86114285
申请日：1986-10-15
发明人： Yanai, Akira , Ueda, Yoshizumi
摘要： Disclosed is a plasmid with wide host range which can self-replicate in a microorganism belonging to the family Enterobacteriaceae. The production of L-threonine may be promoted by using a transformant transformed with a new recombinant DNA obtained by inserting a gene responsible for the production of L-threonine derived from a microorganism belonging to the genus Providencia, to the above plasmid.
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公开(公告)号：EP0219808A2
公开(公告)日：1987-04-29
申请号：EP86114285.9
申请日：1986-10-15
发明人： Yanai, Akira , Ueda, Yoshizumi
IPC分类号： C12N15/74
摘要： Disclosed is a plasmid with wide host range which can self-replicate in a microorganism belonging to the family Enterobacteriaceae. The production of L-threonine may be promoted by using a transformant transformed with a new recombinant DNA obtained by inserting a gene responsible for the production of L-threonine derived from a microorganism belonging to the genus Providencia, to the above plasmid.
摘要翻译： 公开了一种具有宽宿主范围的质粒，其可以在属于肠杆菌科的微生物中自我复制。 L-苏氨酸的生产可以通过使用通过将来源于普罗维登西菌属的微生物的产生L-苏氨酸的基因插入到上述质粒而获得的新的重组DNA转化的转化体来促进。
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