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公开(公告)号：EP1075656B1
公开(公告)日：2011-07-06
申请号：EP99918252.0
申请日：1999-05-04
发明人： EICHEN, Yoav , SIVAN, Uri , BRAUN, Erez
IPC分类号： G01N27/327 , G01N33/543 , G01N27/00 , C12Q1/68
CPC分类号： C12Q1/6825 , C12Q1/6816 , C12Q1/6834 , G01N33/5438
摘要： The invention concerns a system, device, kit and method for detecting the presence, or concentration of a target in a sample. An assay set comprising at least two spaced apart electrodes is used, comprising a recognition moiety, capable of specific binding to the target, which is attached to at least one of the electrodes or the substrate therein between. If the recognition moiety binds the target then a conductive bridge can be formed between the electrodes, based on the complex between the recognition moiety and the target. The conductive bridge is formed by using nucleation-center forming entities attached to the complexes or to the targets from which a conductive substance is substantially grown. Alternatively the conducting bridge forms a conductive polymer between the electrodes.
摘要翻译： 本发明涉及用于检测样品中靶的存在或浓度的系统，装置，试剂盒和方法。 使用包含至少两个间隔开的电极的测定组，其包含能够特异性结合靶的识别部分，其连接到至少一个电极或其中的基板之间。 如果识别部分结合靶，则可以基于识别部分和靶之间的复合物在电极之间形成导电桥。 导电桥是通过使用连接到复合物或基本上生长导电物质的靶的成核中心形成实体形成的。 或者，导电桥在电极之间形成导电聚合物。
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公开(公告)号：EP1125128B1
公开(公告)日：2006-03-08
申请号：EP99952775.7
申请日：1999-10-27
发明人： BRAUN, Erez , EICHEN, Yoav , SIVAN, Uri
IPC分类号： G01N33/543 , G01N1/30 , G01N33/58
CPC分类号： G01N33/585 , C12Q1/6834 , G01N1/30 , G01N33/5438 , C12Q2527/127
摘要： A method for depositing gold on a substrate is provided. By this aspect, nucleation centers are bound, deposited or formed at one or more sites on the substrate, the substrate is then contacted with a treatment composition which comprises soluble gold-providing agent from which gold is deposited onto a nucleation center to yield gold metal deposits. The method of the invention may be used for a variety of image enhancing techniques as well as diagnostic and analyte detection techniques.
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公开(公告)号：EP1075656A1
公开(公告)日：2001-02-14
申请号：EP99918252.0
申请日：1999-05-04
发明人： EICHEN, Yoav , SIVAN, Uri , BRAUN, Erez
IPC分类号： G01N27/327 , G01N33/543 , G01N27/00 , C12Q1/68
CPC分类号： C12Q1/6825 , C12Q1/6816 , C12Q1/6834 , G01N33/5438
摘要： The invention concerns a system, device, kit and method for detecting the presence, or concentration of a target in a sample. An assay set comprising at least two spaced apart electrodes is used, comprising a recognition moiety, capable of specific binding to the target, which is attached to at least one of the electrodes or the substrate therein between. If the recognition moiety binds the target then a conductive bridge can be formed between the electrodes, based on the complex between the recognition moiety and the target. The conductive bridge is formed by using nucleation-center forming entities attached to the complexes or to the targets from which a conductive substance is substantially grown. Alternatively the conducting bridge forms a conductive polymer between the electrodes.
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公开(公告)号：EP0998759A1
公开(公告)日：2000-05-10
申请号：EP98932493.4
申请日：1998-07-14
发明人： BRAUN, Erez , EICHEN, Yoav , SIVAN, Uri , BEN-JOSEPH, Gdalyahu
CPC分类号： H01L51/0093 , B82Y10/00 , G06N3/123 , G11C13/0014 , G11C13/0019 , H01L51/0002 , H01L51/0036 , H01L51/0038 , H01L51/0062 , H01L51/0595
摘要： A microelectronic network is fabricated on a fibrous skeleton by binding or complexing electronically functional substances to the nucleic acid skeleton. The skeleton comprises fibers with nucleotide chains. The assembly of the fibers into a network is based on interactions of nucleotide chain portions of different fibers.
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公开(公告)号：EP1125128A1
公开(公告)日：2001-08-22
申请号：EP99952775.7
申请日：1999-10-27
发明人： BRAUN, Erez , EICHEN, Yoav , SIVAN, Uri
IPC分类号： G01N33/543 , G01N1/30 , G01N33/58
CPC分类号： G01N33/585 , C12Q1/6834 , G01N1/30 , G01N33/5438 , C12Q2527/127
摘要： A method for depositing gold on a substrate is provided. By this aspect, nucleation centers are bound, deposited or formed at one or more sites on the substrate, the substrate is then contacted with a treatment composition which comprises soluble gold-providing agent from which gold is deposited onto a nucleation center to yield gold metal deposits. The method of the invention may be used for a variety of image enhancing techniques as well as diagnostic and analyte detection techniques.
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公开(公告)号：EP3278369A1
公开(公告)日：2018-02-07
申请号：EP16771537.4
申请日：2016-03-31
发明人： EICHEN, Yoav , TESSLER, Nir , KUMAR, Pramod , GERCHIKOV, Yulia
IPC分类号： H01L29/786 , H01L21/335
CPC分类号： H01L29/04 , H01L29/4925 , H01L29/78672 , H01L29/7869 , H01L29/78696 , H01L51/0053 , H01L51/0067 , H01L51/0068 , H01L51/0558 , H01L2251/5369
摘要： A transistor device is described, the transistor comprising: a channel region in contact with the gate insulator and source and drain electrodes in contact with the channel region and arranged in a spaced-apart relationship. The channel region is configured with discontinuity in a material path of the channel, located between the source and drain electrodes. The channel being formed by a plurality of discrete semiconductor particles, distributed irregularly within the channel region, and a plurality of electrically conducting particles. The electrically conducting particles connect at least some of said semiconducting particles to one another to provide continuous path for electric coupling between said at least some semiconductor particles, forming an electrical path between the source and drain electrodes.
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