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公开(公告)号：EP2678319A2
公开(公告)日：2014-01-01
申请号：EP12749134.8
申请日：2012-02-22
IPC分类号： C07D235/28 , A61K31/4184 , A61P31/00
CPC分类号： C07D235/28 , A61K31/4184 , A61K31/496 , C07D263/58 , C07D405/12
摘要： The present disclosure relates to benzimidazole-benzamide derivatives, and the use thereof, e.g., to treat infections.
摘要翻译： 本公开涉及苯并咪唑 - 苯甲酰胺衍生物及其用于例如治疗感染的用途。
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公开(公告)号：EP3578548A1
公开(公告)日：2019-12-11
申请号：EP19169311.8
申请日：2012-02-22
IPC分类号： C07D235/28 , A61K31/4184 , A61P31/00
摘要： The present disclosure relates to benzimidazole-benzamide derivatives, and the use thereof, e.g., to treat infections.
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公开(公告)号：EP2678319B1
公开(公告)日：2019-04-17
申请号：EP12749134.8
申请日：2012-02-22
IPC分类号： C07D235/28 , A61K31/4184 , A61P31/00
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公开(公告)号：EP3563862A1
公开(公告)日：2019-11-06
申请号：EP19160530.2
申请日：2010-03-19
摘要： The disclosure relates to methods for treating a subject suffering from a burn injury or associated complications by administering to the subject an effective amount of an aromatic-cationic peptide. For example, a burn injury may be associated with distant pathophysiological effects, such as hypermetabolism, skeletal muscle dysfunction, and organ damage. The disclosure also relates to methods for protecting a subject from a burn injury by administering an effective amount of an aromatic-cationic peptide to a subject at risk of a burn injury.
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5.发明公开METHODS FOR THE PREVENTION AND TREATMENT OF BURN INJURIES AND SECONDARY COMPLICATIONS 有权D-Arg-2'6'-二甲基酪氨酸-LYS-PHE-NH2以防止和烧伤的治疗及相关继发性并发症
公开(公告)号：EP2408463A2
公开(公告)日：2012-01-25
申请号：EP10764805.7
申请日：2010-03-19
IPC分类号： A61K38/07
CPC分类号： A61K38/07 , A61K9/0014 , A61K9/0019
摘要： The disclosure relates to methods for treating a subject suffering from a burn injury or associated complications by administering to the subject an effective amount of an aromatic-cationic peptide. For example, a burn injury may be associated with distant pathophysiological effects, such as hypermetabolism, skeletal muscle dysfunction, and organ damage. The disclosure also relates to methods for protecting a subject from a burn injury by administering an effective amount of an aromatic-cationic peptide to a subject at risk of a burn injury.
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6.发明公开D-ARG-2'6'-DIMETHYLTYROSINE-LYS-PHE-NH2 FOR USE IN THE PREVENTION AND TREATMENT OF BURN INJURIES 审中-公开D-ARG-2'6'-DIMETHYLTYROSINE-LYS-PHE-NH2用于预防和治疗烧伤
公开(公告)号：EP3199173A1
公开(公告)日：2017-08-02
申请号：EP16188118.0
申请日：2010-03-19
CPC分类号： A61K38/07 , A61K9/0014 , A61K9/0019
摘要： The disclosure relates to methods for treating a subject suffering from a burn injury or associated complications by administering to the subject an effective amount of an aromatic-cationic peptide. For example, a burn injury may be associated with distant pathophysiological effects, such as hypermetabolism, skeletal muscle dysfunction, and organ damage. The disclosure also relates to methods for protecting a subject from a burn injury by administering an effective amount of an aromatic-cationic peptide to a subject at risk of a burn injury.
摘要翻译： 本公开涉及通过向受试者施用有效量的芳香族阳离子肽来治疗患有烧伤或相关并发症的受试者的方法。 例如，烧伤可能与远处的病理生理效应有关，如高代谢，骨骼肌功能障碍和器官损伤。 本公开还涉及通过将有效量的芳香族阳离子肽给予处于灼伤风险中的受试者而保护受试者免于灼伤。
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7.发明授权D-ARG-2'6'-DIMETHYLTYROSINE-LYS-PHE-NH2 FOR USE IN THE PREVENTION AND TREATMENT OF BURN INJURIES AND SECONDARY COMPLICATIONS 有权D-Arg-2'6'-二甲基酪氨酸-LYS-PHE-NH2以防止和烧伤的治疗及相关继发性并发症
公开(公告)号：EP2408463B1
公开(公告)日：2016-10-19
申请号：EP10764805.7
申请日：2010-03-19
CPC分类号： A61K38/07 , A61K9/0014 , A61K9/0019
摘要： The disclosure relates to methods for treating a subject suffering from a burn injury or associated complications by administering to the subject an effective amount of an aromatic-cationic peptide. For example, a burn injury may be associated with distant pathophysiological effects, such as hypermetabolism, skeletal muscle dysfunction, and organ damage. The disclosure also relates to methods for protecting a subject from a burn injury by administering an effective amount of an aromatic-cationic peptide to a subject at risk of a burn injury.
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8.发明公开
公开(公告)号：EP3906933A1
公开(公告)日：2021-11-10
申请号：EP21158725.8
申请日：2010-03-19
摘要： The disclosure relates to methods for treating a subject suffering from a burn injury or associated complications by administering to the subject an effective amount of an aromatic-cationic peptide. For example, a burn injury may be associated with distant pathophysiological effects, such as hypermetabolism, skeletal muscle dysfunction, and organ damage. The disclosure also relates to methods for protecting a subject from a burn injury by administering an effective amount of an aromatic-cationic peptide to a subject at risk of a burn injury.
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9.发明授权
公开(公告)号：EP3199173B1
公开(公告)日：2019-04-24
申请号：EP16188118.0
申请日：2010-03-19
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