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公开(公告)号:EP3269707B1
公开(公告)日:2020-08-19
申请号:EP16761835.4
申请日:2016-03-10
发明人: KANBARA, Tadashi , NOGUCHI, Tsuyoshi , TAKATA, Toshikazu , SOGAWA, Hiromitsu , TSUTSUBA, Toyokazu
IPC分类号: C07C291/06 , C08K5/32 , C08L101/00 , C07C323/47 , C07F9/40
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公开(公告)号:EP3805201A1
公开(公告)日:2021-04-14
申请号:EP19811486.0
申请日:2019-05-27
IPC分类号: C07C291/06 , C07C205/28 , C07C323/07 , C07C323/57 , C09K3/18
摘要: The present invention provides a compound represented by formula (I) wherein symbols in the formula are as defined in the specification.
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公开(公告)号:EP3269707A1
公开(公告)日:2018-01-17
申请号:EP16761835.4
申请日:2016-03-10
发明人: KANBARA, Tadashi , NOGUCHI, Tsuyoshi , TAKATA, Toshikazu , SOGAWA, Hiromitsu , TSUTSUBA, Toyokazu
IPC分类号: C07C291/06 , C08K5/32 , C08L101/00
摘要: The present invention provides a compound of the formula (I) :
wherein, A is R 6 (R 7 ), N, O, S, or -NR 5 -; R 6 is an s-valent organic group; R 7 is each independently, -O-, -S-, -NR 5 - or-O-P(=O)OR 4' -; R 2 and R 3 are each independently a hydrogen atom or a hydrocarbon group; R 4' is each independently, a hydrocarbon group; R 5 is each independently, a hydrogen atom or a hydrocarbon group; and s is an integer of 1-10.摘要翻译: 本发明提供了式(I)的化合物:其中,A是R6(R7),N,O,S或-NR5-; R6是s价有机基团; R7各自独立地为-O - , - S - , - NR5-或-O-P(= O)OR4' - ; R2和R3各自独立地为氢原子或烃基; R4'各自独立地为烃基; R5各自独立地为氢原子或烃基; s是1-10的整数。
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公开(公告)号:EP3269708A1
公开(公告)日:2018-01-17
申请号:EP16761836.2
申请日:2016-03-10
发明人: KANBARA, Tadashi , NOGUCHI, Tsuyoshi , TAKATA, Toshikazu , SOGAWA, Hiromitsu , MONJIYAMA, Shunsuke , TSUTSUBA, Toyokazu
IPC分类号: C07C291/06 , C08G63/08 , C08G63/16 , C08G63/91 , C08K5/32 , C08L101/02
CPC分类号: C07C291/06 , C08F120/36 , C08G63/08 , C08G63/16 , C08G63/6856 , C08G63/91 , C08G63/916 , C08K5/32 , C08L101/02
摘要: The present invention provides a compound of the formula (I) :
wherein, R 1 is a hydrogen atom or a hydrocarbon group; R 2 is -R 4 -R 5 ; R 3 is -R 4 -R 5 or -R 4 -R 6 ; R 4 is a divalent organic group; R 5 is OH, SH, COOH or NHR 9 ; R 9 is a hydrogen atom or an alkyl group having 1-6 carbon atoms; and R 6 is a hydrogen atom or an alkyl group having 1-6 carbon atoms.摘要翻译: 本发明提供了式(I)的化合物:其中,R 1是氢原子或烃基; R2是-R4-R5; R3是-R4-R5或-R4-R6; R4是二价有机基团; R5是OH,SH,COOH或NHR9; R9是氢原子或具有1-6个碳原子的烷基; 并且R6是氢原子或具有1-6个碳原子的烷基。
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公开(公告)号:EP2348021A1
公开(公告)日:2011-07-27
申请号:EP09821794.6
申请日:2009-10-21
发明人: TAKATA, Toshikazu , KOYAMA, Yasuhito , NAKAZONO, Kazuko , HASEGAWA, Toshihide , LEE, Young-Gi , ONO, Nobufumi , NISHIO, Kazuto , FUJITA, Yoshihiko
IPC分类号: C07D323/00 , A61K31/357 , A61P35/00
CPC分类号: C07D323/00 , A61K31/357
摘要: An antitumor agent which is not easily excreted from tumor cells and is suitable for a topical treatment. Specifically disclosed is a rotaxane compound with contains a compound represented by chemical formula 1 as the base structure. (In chemical formula 1, m ≥ 2, n ≥ 3, and X represents an anionic molecule or an anionic atom
摘要翻译: 一种不容易从肿瘤细胞排出并适用于局部治疗的抗肿瘤剂。 具体公开的是含有以化学式1表示的化合物作为基础结构的轮烷化合物。 (化学式1中,m‰¥2,n‰3,X表示阴离子分子或阴离子原子
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公开(公告)号:EP3786169A1
公开(公告)日:2021-03-03
申请号:EP19791854.3
申请日:2019-04-25
IPC分类号: C07F7/18 , C07D323/00 , C08K3/36 , C08K5/16 , C08L9/00 , C08L101/02
摘要: A rotaxane compound comprising one or more cyclic molecules and an axial molecule penetrating through inner holes of the cyclic molecules and having cap structures disposed lest the cyclic molecules should be detached, where one of the cyclic molecule and the axial molecule has one of a functional group being capable of reacting with silica and a functional group being capable of reacting with a carbon-carbon unsaturated bond, and the other of the cyclic molecule and the axial molecule has the other of the functional group being capable of reacting with silica and the functional group being capable of reacting with a carbon-carbon unsaturated bond.
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公开(公告)号:EP2348021B1
公开(公告)日:2013-07-24
申请号:EP09821794.6
申请日:2009-10-21
发明人: TAKATA, Toshikazu , KOYAMA, Yasuhito , NAKAZONO, Kazuko , HASEGAWA, Toshihide , LEE, Young-Gi , ONO, Nobufumi , NISHIO, Kazuto , FUJITA, Yoshihiko
IPC分类号: C07D323/00 , A61K31/357 , A61P35/00
CPC分类号: C07D323/00 , A61K31/357
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