摘要:
The present disclosure relates to a hydrogel composition and methods on using the same. The hydrogel composition may include precursors that react with each other upon contact as well as precursors that react upon contact with an initiator. In embodiments, the resulting hydrogels may have varying levels of crosslinking with both denser and less dense regions.
摘要:
The present disclosure relates to a hydrogel composition and methods on using the same. The hydrogel composition may include precursors that react with each other upon contact as well as precursors that react upon contact with an initiator. In embodiments, the resulting hydrogels may have varying levels of crosslinking with both denser and less dense regions.
摘要:
A wound closure device for use in sealing a tissue perforation created by an access device, comprising: an elongate body having a distal portion and a proximal portion, and a plurality of barbs extending from a surface thereof and extending at least partially in a distal direction; wherein the elongate body is a suture, a plug member having a tissue facing surface coupled to the distal end of the elongate body, wherein the elongate body, the plug member, or both, comprise at least one reactive group selected from the group consisting of isocyanate, N-hydroxy succinimide, cyanoacrylate, aldehyde, genipin, polylysine, diimide, diisocyanate, cyanamide, carbodiimide, dimethyl adipimidate, and combinations thereof; wherein the wound closure device further comprises an inner and a relatively rigid outer member each having an opening extending therethrough and each moveably positioned on the elongate body.
摘要:
Applicator tips in accordance with the present disclosure include a body portion and dispensing tip. The body portion includes a proximal end having an inlet adapted for fluid communication with a fluid source, a distal end including an opening, and a mixing chamber disposed therebetween. The mixing chamber includes at least one mixing ball and at least one biologically active agent disposed therein. The dispensing tip defines a lumen therethrough. The lumen is in fluid communication with the opening of the distal end of the body portion and includes an outlet for passage of a fluid therethrough.
摘要:
The present disclosure is directed to an implantable repository (200) including a housing (202) comprising at least one bioactive agent (203a) and at least one attachment member (204) coupled to the housing, the at least one attachment member configured to couple the implantable repository to at least one of a medical device and a tissue surface.
摘要:
An osteochondral plug includes a first scaffold and a second scaffold. The first scaffold may be a solid scaffold containing one or more pendant reactive functional groups. The second scaffold capable of reacting with the one or more pendant reactive functional groups of the first scaffold
摘要:
A medical device for wound closure, including an elongate body with a plurality of portions and a perforated region disposed therebetween. The medical device may also include an alignment member. The wound plug may also have a first position for insertion, the portions being mechanically coupled to each other, and a second position where one or more of the portions are spatially separated.
摘要:
A surgical port (100) includes a port body (1) having a lumen (3,4,5) extending therethrough and a plate (2) having an opening. The port body may be made from foam. The port is configured such that rotation of the plate with respect to the port body aligns the opening and lumen defining a passage therethrough for the insertion of surgical instruments.