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公开(公告)号：EP3062767A1
公开(公告)日：2016-09-07
申请号：EP14859235.5
申请日：2014-10-30
申请人： Unigen, Inc. , Unigen, Inc.
发明人： BROWNELL, Lidia, Alfaro , CHU, Min , CORNELIUSEN, Brandon , HONG, Mei-Feng , HWANG, Ji-Hye , HYUN, Eu-Jin , JIA, Qi , JIAO, Ping , KIM, Mi-Ran , LEE, Bo-Su , LEE, Young-Chul , NAM, Jeong-Bum , OH, Mi-Sun , YIMAM, Mesfin
CPC分类号： A61K8/97 , A61K8/0204 , A61K8/36 , A61K8/4926 , A61K8/4973 , A61K2800/42 , A61K2800/522 , A61K2800/5922 , A61Q19/00 , A61Q19/06 , A61Q19/08
摘要： The present disclosure provides a mixture of sugar apple and rosemary extracts, optionally in combination with prickly ash extract, for use as skin care compositions.
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公开(公告)号：EP3010928A1
公开(公告)日：2016-04-27
申请号：EP14813460.4
申请日：2014-06-16
申请人： Unigen, Inc. , Unigen, Inc.
发明人： BROWNELL, Lidia, Alfaro , CHU, Min , HONG, Mei-Feng , HYUN, Eu-Jin , JIA, Qi , JIAO, Ping , KIM, Hyun-Jin , KIM, Mi-Ran , KIM, Tae-Woo , LEE, Bo-Su , LEE, Young-Chul , MOORE, Breanna , NAM, Jeong-Bum , OH, Mi-Sun , PARK, Mi-Hye , YIMAM, Mesfin , ZHANG, Qian
IPC分类号： C07H15/20 , C07K14/415 , A61K36/605 , A61K36/48 , A61P19/02
CPC分类号： A61K36/605 , A61K31/05 , A61K31/352 , A61K31/353 , A61K31/7008 , A61K31/7028 , A61K31/7034 , A61K36/48 , A61K36/534 , A61K2300/00
摘要： The present disclosure provides mixtures of prenylated flavonoids, stilbenes, or both with flavans or curcuminoids or both capable of modulating joint inflammation, joint pain, joint stiffness, cartilage degradation, or improving mobility, range of motion, flexibility, joint physical function, or any combination thereof. Such a mixture of prenylated flavonoids, stilbenes, or both with flavans or curcuminoids or both can optionally be used in combination with other joint management agents, such as non-steroidal anti-inflammatory agents/analgesics, COX/LOX inhibiting agents, glucosamine compounds, neuropathic pain relief agents, or the like.
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公开(公告)号：EP1796704A2
公开(公告)日：2007-06-20
申请号：EP05808582.0
申请日：2005-09-01
申请人： Unigen, Inc.
发明人： JO, Tae-Hyung, Woosung Apt. 302-201 , WOO, Sung-Sick , CHA, Ji-Min , KIM, Dong-Seon , LEE, Young-Chul , DO, Seon-Gil Hanul 2nd Apt. 201-1106, 724 , KIM, Jong-Han , KIM, Tae-Woo , SUNG, Hee-Sun
IPC分类号： A61K36/74 , A61K36/82 , A61K36/539
CPC分类号： A61K36/74 , A61K36/539 , A61K36/82 , A61K2300/00
摘要： The present invention relates to a composition for the prevention or treatment of physiological and pathological disorders mediated by cyclooxygenase (COX) and/or 5 -lipoxygenase (5-LO) comprising Uncaria genus plant, in particular, Uncaria gambir, or its extract, and to a combined composition of said Uncaria genus plant extract and Scutellaria baicalensis extract and/or Camellia sinensis extract. The present composition shows excellent COX and/5-LO inhibition effects, and thus can be used for the prevention or treatment of disease and disorders mediated by various COX pathway and/or 5-LO pathway, including osteoarthritis and rheumatoid arthritis.
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公开(公告)号：EP1863498A2
公开(公告)日：2007-12-12
申请号：EP06716434.3
申请日：2006-03-17
申请人： Unigen, Inc.
发明人： WOO, Sung-Sick , KIM, Dong-Seon , DO, Seon-Gil , LEE, Young-Chul , OH, Mi-Sun , CHA, Ji-Min , JO, Tae-Hyung
IPC分类号： A61K31/7032 , A61K31/352 , A61K36/899 , A61P37/08
CPC分类号： A61K36/899 , A61K31/352 , A61K31/353 , A61K31/7032 , A61K36/886
摘要： The present invention relates to a pharmaceutical composition for the prevention or treatment of diseases mediated by excessive histamine comprising naturally-derived isoorientin, a use of isoorientin for the manufacture of a medicament for the prevention or treatment of diseases mediated by excessive histamine, and a method for preventing or treating diseases mediated by excessive histamine comprising administering a therapeutically effective amount of isoorientin to a subject. The composition, use and method of the present invention show excellent histamine suppression effects, and so can be used for the prevention or treatment of various kinds of allergic disease, atopic disease, inflammatory disease, skin disease, hyperacidity and nervous system disorder.
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