专利检索 ap:("University of Saskatchewan") AND inv:"HILL, Janet Elizabeth" 第 1 页

1.

发明公开
METHODS AND COMPOSITIONS FOR THE DETECTION AND IDENTIFICATION OF ARCHAEA BASED ON THE TYPE II CHAPERONIN (THERMOSOME) GENE 审中-公开
标题翻译：方法和组合物用于检测和用于识别古细菌基于所述CHAPERONIN-（THERMOSOM-）GENE TYPE II

公开(公告)号：EP2560983A1

公开(公告)日：2013-02-27

申请号：EP11758702.2

申请日：2011-03-08

申请人： University Of Saskatchewan

发明人： HILL, Janet Elizabeth , CHABAN, Bonnie Laura

IPC分类号： C07H21/04 , C07H21/00 , C12P19/34 , C12Q1/02 , C12Q1/68 , C07K14/195 , C12N15/31

CPC分类号： C12Q1/689 , C12N15/11 , C12Q2600/16

摘要： The present invention relates to primers for the universal amplification and detection of Archaea, which primers are designed based on a multiple sequence alignment of Archaea Type II chaperonin (thermosome) genes. For detection of Archaea having templates with a GC content of below 60%, primers are designed so that inosine residues are found at degenerate positions. For amplification of higher GC content templates, degenerate positions are replaced with specific nucleotide bases found in the high GC organism. The primers are useful for detecting, identifying and quantifying Archaea in a sample and for determining a phylogenetic relationship of a test Archaea organism.

2.

发明公开
DIAGNOSTIC METHOD FOR COLITIS 审中-公开
标题翻译：诊断步骤FOR肠炎

公开(公告)号：EP2593550A1

公开(公告)日：2013-05-22

申请号：EP11806184.5

申请日：2011-07-18

申请人： University of Saskatchewan

发明人： HARDING, John Clare Samuel , HILL, Janet Elizabeth , CHIRINO, Manuel , RUBIN, Joseph

IPC分类号： C12N15/61 , C07K14/20 , C07K16/12 , C07K16/40 , C12N1/20 , C12N15/31 , C12N15/53 , C12N15/54 , C12N15/55 , C12N9/02 , C12N9/10 , C12N9/12 , C12N9/16 , C12N9/90 , C12Q1/68 , G01N33/569 , G01N33/573 , G01N33/68 , C40B30/04

CPC分类号： C07K14/195 , C12Q1/6883 , C12Q1/689 , C12Q2600/158 , G01N33/56911 , G01N2333/20 , G01N2800/067

摘要： A method of screening for, diagnosing or detecting the presence of Brachyspira sp. Sask30446 and/or colitis in a subject comprising detecting a Brachyspira sp. Sask30446 polynucleotide or polypeptide in a sample of the subject, wherein detection of the Brachyspira sp. Sask30446 polynucleotide or polypeptide is indicative of the presence Brachyspira sp. Sask30446 and/or that the subject has colitis or has an increased risk of developing colitis.

3.

发明公开
ISOLATED BRACHYSPIRA AND METHODS AND COMPOSITIONS FOR EXPANDING AND ISOLATING BRACHYSPIRA 审中-公开
标题翻译：隔离短螺旋体和膨胀和隔离短螺旋体的方法和组合物

公开(公告)号：EP2734614A1

公开(公告)日：2014-05-28

申请号：EP12814810.3

申请日：2012-07-18

申请人： University of Saskatchewan

发明人： HARDING, John Clare Samuel , HILL, Janet Elizabeth , RUBIN, Joseph , CHIRINO TREJO, Manuel

IPC分类号： C12N1/20 , A61K39/02 , A61P31/04 , A61P37/04 , C07K16/12 , C12Q1/68 , G01N33/50 , C07K14/20

CPC分类号： C07K14/20 , A61K39/00 , C07K16/1207 , C12N1/20 , C12R1/01

摘要： The disclosure provides isolated-, compositions comprising - and methods of culturing - a Brachyspira sp. Sask30446 organism. The method comprises inoculating a liquid media or solid media with a sample comprising the Brachyspira sp. Sask30446 organism and incubating the liquid media or solid media at a temperature between 25-44oC under anaerobic conditions. Also provided is isolated Brachyspira sp. Sask30446 organism, compositions comprising Brachyspira sp. Sask30446 organism and methods and uses thereof.