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1.发明授权FE(III)-2,4-DIOXO-1-CARBONYL-KOMPLEXVERBINDUNGEN ZUR VERWENDUNG BEI DER BEHANDLUNG UND DER PROPHYLAXE VON EISENMANGELERSCHEINUNGEN UND EISENMANGELANÄMIEN 有权FE（III）-2,4-二氧代-1-羰基络合物化合物，其用在治疗和预防缺铁出现和缺铁性贫血的
公开(公告)号：EP2714030B1
公开(公告)日：2015-08-12
申请号：EP12729036.9
申请日：2012-05-30
发明人： BARK, Thomas , BUHR, Wilm , BURCKHARDT, Susanna , BURGERT, Michael , CANCLINI, Camillo , DÜRRENBERGER, Franz , FUNK, Felix , GEISSER, Peter , KALOGERAKIS, Aris , MAYER, Simona , PHILIPP, Erik , REIM, Stefan , SIEBER, Diana , SCHMITT, Jörg , SCHWARZ, Katrin , KLOTZ, Jürgen
IPC分类号： A61K31/295 , A61K31/4453 , A61K31/5375 , A61P7/06
CPC分类号： A61K31/555 , A61K31/295 , A61K31/4453 , A61K31/5375 , A61K33/26 , A61K45/06 , C07F15/025
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公开(公告)号：EP2978427B1
公开(公告)日：2018-08-08
申请号：EP14713115.5
申请日：2014-03-27
发明人： BARK, Thomas , BUHR, Wilm , BURCKHARDT, Susanna , BURGERT, Michael , CANCLINI, Camillo , DÜRRENBERGER, Franz , FUNK, Felix , GEISSER, Peter Otto , KALOGERAKIS, Aris , MAYER, Simona , PHILIPP, Erik , SIEBER, Diana , SCHMITT, Jörg , SCHWARZ, Katrin , REIM, Stefan
IPC分类号： A61K31/4412 , A61P7/06 , A61K33/26
CPC分类号： A61K31/555 , A61K31/4412 , A61K33/26 , A61K45/06 , A61K2300/00
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公开(公告)号：EP4326717A1
公开(公告)日：2024-02-28
申请号：EP22724448.0
申请日：2022-04-21
发明人： BUHR, Wilm , KALOGERAKIS, Aris , UMLAND, Klaus-Daniel , REIM, Stefan , MANOLOVA, Vania , ALTERMATT, Patrick , FLACE, Anna
IPC分类号： C07D413/14 , C07D471/04 , C07D491/056 , A61P7/00 , A61K31/437
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公开(公告)号：EP3365339A1
公开(公告)日：2018-08-29
申请号：EP16797462.5
申请日：2016-10-21
发明人： DÜRRENBERGER, Franz , BURGERT, Michael , BURCKHARDT, Susanna , BUHR, Wilm , KALOGERAKIS, Aris , REIM, Stefan , MANOLOVA, Vania , BOYCE, Susan , YARNOLD, Christopher John , PENA, Paula , SHEPHERD, Jon , LECCI, Cristina , JARJES-PIKE, Richard , SCOTT, John
IPC分类号： C07D413/14 , C07D417/14 , C07D417/12 , C07D471/04 , A61P3/12 , A61P7/00 , A61P25/00 , A61K31/4184 , A61K31/427 , A61K31/4355 , A61K31/437 , A61K31/4375 , A61K31/4439 , A61K31/444 , A61K31/4985 , A61K31/501 , A61K31/506 , A61K31/5377 , A61K31/55
CPC分类号： C07D413/14 , A61K31/16 , A61K31/4184 , A61K31/426 , A61K31/427 , A61K31/435 , A61K31/4355 , A61K31/437 , A61K31/4375 , A61K31/4422 , A61K31/4439 , A61K31/444 , A61K31/4709 , A61K31/4725 , A61K31/497 , A61K31/4985 , A61K31/501 , A61K31/506 , A61K31/5377 , A61K31/55 , A61K36/9066 , A61K45/06 , A61K2300/00 , A61P3/12 , A61P7/06 , A61P25/16 , A61P25/28 , C07D277/56 , C07D401/14 , C07D403/14 , C07D413/04 , C07D417/12 , C07D417/14 , C07D471/04 , C07D487/04 , Y02A50/411
摘要： The invention relates to novel ferroportin inhibitors of the general formula (I) pharmaceutical compositions comprising them and the use thereof as medicaments, in particular for the prophylaxis and/or treatment of diseases caused by a lack of hepcidin or iron metabolism disorders, such as particularly iron overload states such as in particular thalassemia and hemochromatosis.
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5.发明授权FE(III)-KOMPLEXVERBINDUNGEN ZUR BEHANDLUNG UND PROPHYLAXE VON EISENMANGELERSCHEINUNGEN UND EISENMANGELANÄMIEN 有权FE（III）络合物用于治疗和预防铁缺乏症和铁缺乏症
公开(公告)号：EP2934508B1
公开(公告)日：2017-12-06
申请号：EP13814901.8
申请日：2013-12-19
发明人： BARK, Thomas , BUHR, Wilm , BURCKHARDT, Susanna , BURGERT, Michael , CANCLINI, Camillo , DÜRRENBERGER, Franz , FUNK, Felix , GEISSER, Peter Otto , KALOGERAKIS, Aris , MAYER, Simona , PHILIPP, Erik , REIM, Stefan , SIEBER, Diana , SCHMITT, Jörg , SCHWARZ, Katrin
IPC分类号： A61K31/295 , A61K31/555 , A61P7/06 , A61K45/06
CPC分类号： A61K31/295 , A61K31/555 , A61K45/06
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公开(公告)号：EP2549991B1
公开(公告)日：2017-11-22
申请号：EP11710182.4
申请日：2011-03-22
发明人： BARK, Thomas , BUHR, Wilm , BURCKHARDT, Susanna , BURGERT, Michael , CANCLINI, Camillo , DÜRRENBERGER, Franz , FUNK, Felix , GEISSER, Peter , KALOGERAKIS, Aris , MAYER, Simona , PHILIPP, Erik , REIM, Stefan , SIEBER, Diana , SCHMITT, Jörg , SCHWARZ, Katrin
IPC分类号： A61K31/295 , A61K31/4453 , A61P7/06 , A61K45/06 , A61K9/00 , A61K31/555 , C07F15/02
CPC分类号： A61K31/295 , A61K9/0053 , A61K31/4453 , A61K31/555 , A61K45/06 , C07F15/025
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7.发明公开FE(III)-2,4-DIOXO-1-CARBONYL-KOMPLEXVERBINDUNGEN ZUR BEHANDLUNG UND PROPHYLAXE VON EISENMANGELERSCHEINUNGEN UND EISENMANGELANÄMIEN 有权FE（III）-2,4-二氧代-1-羰基络合物化合物，其用在治疗和预防缺铁出现和缺铁性贫血的
公开(公告)号：EP2714030A1
公开(公告)日：2014-04-09
申请号：EP12729036.9
申请日：2012-05-30
发明人： BARK, Thomas , BUHR, Wilm , BURCKHARDT, Susanna , BURGERT, Michael , CANCLINI, Camillo , DÜRRENBERGER, Franz , FUNK, Felix , GEISSER, Peter , KALOGERAKIS, Aris , MAYER, Simona , PHILIPP, Erik , REIM, Stefan , SIEBER, Diana , SCHMITT, Jörg , SCHWARZ, Katrin , KLOTZ, Jürgen
IPC分类号： A61K31/295 , A61K31/4453 , A61K31/5375 , A61P7/06
CPC分类号： A61K31/555 , A61K31/295 , A61K31/4453 , A61K31/5375 , A61K33/26 , A61K45/06 , C07F15/025
摘要： The invention relates to iron(III) 2,4-dioxo-1-carbonyl complexes and to pharmaceutical compositions comprising them for use in the treatment for prophylaxis of iron deficiency symptoms and iron deficiency anaemias.
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8.发明公开FE(III)-KOMPLEXVERBINDUNGEN ZUR BEHANDLUNG UND PROPHYLAXE VON EISENMANGELERSCHEINUNGEN UND EISENMANGELANÄMIEN 有权FE（III）可用于治疗和预防缺铁外观和缺铁性贫血的络合物
公开(公告)号：EP2549991A1
公开(公告)日：2013-01-30
申请号：EP11710182.4
申请日：2011-03-22
发明人： BARK, Thomas , BUHR, Wilm , BURCKHARDT, Susanna , BURGERT, Michael , CANCLINI, Camillo , DÜRRENBERGER, Franz , FUNK, Felix , GEISSER, Peter , KALOGERAKIS, Aris , MAYER, Simona , PHILIPP, Erik , REIM, Stefan , SIEBER, Diana , SCHMITT, Jörg , SCHWARZ, Katrin
IPC分类号： A61K31/295 , A61K31/4453 , A61P7/06
CPC分类号： A61K31/295 , A61K9/0053 , A61K31/4453 , A61K31/555 , A61K45/06 , C07F15/025
摘要： The invention relates to iron(III) complex compounds and pharmaceutical compounds comprising same for use as medicaments, in particular for the treatment and/or for the prophylaxis of iron deficiency symptoms and iron deficiency anemias.
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公开(公告)号：EP2475643A1
公开(公告)日：2012-07-18
申请号：EP10752772.3
申请日：2010-09-06
发明人： DÜRRENBERGER, Franz , BURCKHARDT, Susanna , BUHR, Wilm , GEISSER, Peter, Otto , FUNK, Felix , CORDEN, Vincent, Anthony , COURTNEY, Stephen, Martin , DAVENPORT, Tara , JAEGER, Stefan , RIDGILL, Mark, Peter , SLACK, Mark , YARNOLD, Christopher, John , YAU, Wei, Tsung
IPC分类号： C07D211/58 , C07D401/12 , C07D405/12 , A61K31/496 , A61K31/5377 , A61P7/06 , C07D211/14 , C07D211/62 , C07D213/38 , C07D239/42 , C07D241/20 , C07D307/24 , C07D405/14 , C07D409/12 , C07D295/13
CPC分类号： C07D401/12 , C07D211/14 , C07D211/58 , C07D211/62 , C07D213/38 , C07D239/42 , C07D241/20 , C07D295/13 , C07D307/24 , C07D405/12 , C07D405/14 , C07D409/12
摘要： The invention relates to novel hepcidin antagonists of formula (I), to pharmaceutical compositions containing same, and to the use thereof as a medicament, especially for treating iron metabolism disorders such as especially iron deficiency diseases and anaemia, especially anaemia related to chronic inflammation diseases (ACD; anaemia of chronic disease and AI; anaemia of inflammation).
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公开(公告)号：EP2473486A1
公开(公告)日：2012-07-11
申请号：EP10747859.6
申请日：2010-08-31
发明人： DÜRRENBERGER, Franz , BURCKHARDT, Susanna , GEISSER, Peter, Otto , BUHR, Wilm , FUNK, Felix , BAINBRIDGE, Julia, Marie , CORDEN, Vincent, Anthony , COURTNEY, Stephen, Martin , DAVENPORT, Tara , JAEGER, Stefan , RIDGILL, Mark Peter , SLACK, Mark , YARNOLD, Christopher, John , YAU, Wei, Tsung
IPC分类号： C07D239/47 , C07D251/18 , C07D251/66 , C07D401/04 , C07D401/14 , C07D403/04 , A61K31/53 , A61K31/506 , A61K31/5377 , A61P7/06
CPC分类号： C07D401/04 , C07D239/47 , C07D251/18 , C07D251/66 , C07D401/14 , C07D403/04
摘要： The present invention relates to novel hepcidine antagonists of the formula (I), comprising pharmaceutical compositions and the use thereof as medications, in particular for treating iron metabolism disorders, such as in particular iron deficiency diseases and anemias, in particular anemias in conjunction with chronic inflammatory diseases (ACD, anemia of chronic disease, and AI, anemia of inflammation).
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