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公开(公告)号：EP4366609A1
公开(公告)日：2024-05-15
申请号：EP22838511.8
申请日：2022-07-11
IPC分类号： A61B5/00
CPC分类号： A61B5/02007 , A61B5/0059 , A61B5/4227 , A61B5/489 , A61B2505/0520130101
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2.发明公开INTRA-OPERATIVE FLUORESCENCE SPECTROSCOPY AND APPLICATIONS OF SAME 有权INTRAOPERATIVE FLUORESZENZ-SPEKTROSKOPIE UND ANWENDUNGEN DAVON
公开(公告)号：EP3005941A2
公开(公告)日：2016-04-13
申请号：EP15187369.2
申请日：2009-07-30
发明人： MAHADEVAN-JANSEN, Anita , WHITE, Lisa , PHAY, John , PARAS, Constatine, A. , KANTER BARTZ, Elizabeth , KELLER, Matthew, D. , GASPARINO, Nicole , WHISENANT, Jennifer, Gray , PENCE, Isaac J.
IPC分类号： A61B5/05
CPC分类号： A61B5/415 , A61B5/0071 , A61B5/0075 , A61B5/0086 , A61B5/418 , A61B5/4227 , A61B5/742 , A61B34/20 , A61B2034/2055 , A61B2505/05 , G01N21/6456 , G01N21/65 , G01N2021/6439 , G01N2201/0221
摘要： A method or process for intra-operatively providing anatomical guidance in endocrine surgery. In one embodiment, the process includes the steps of illuminating human tissues (407) in the neck area of a human being in operation with a beam of light (211, 454), obtaining fluorescent data from the light scattered (428, 405) from the human tissues, finding fluorescent signatures from the obtained fluorescent data, and identifying tissues that are corresponding to the fluorescent signatures that represent thyroid or parathyroid tissues.
摘要翻译： 在内分泌手术中手术中提供解剖指导的方法或过程。 在一个实施例中，该方法包括以下步骤：利用光束（211,454）照射在人的颈部区域中的人体组织（407），从光散射（428,405）获得荧光数据， 人组织，从获得的荧光数据中找到荧光标记，以及鉴定与代表甲状腺或甲状旁腺组织的荧光标记相对应的组织。
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3.发明公开PROCESS AND SYSTEM FOR INTRA-OPERATIVE USE OF FLUORESCENCE AND APPLICATIONS OF SAME 审中-公开荧光手术中使用的方法和系统及其应用
公开(公告)号：EP3289972A1
公开(公告)日：2018-03-07
申请号：EP17196217.8
申请日：2009-07-30
发明人： MAHADEVAN-JANSEN, Anita , WHITE, Lisa , PHAY, John , PARAS, Constantine, A. , KANTER BARTZ, Elizabeth , KELLER, Matthew, D. , GASPARINO, Nicole , WHISENANT, Jennifer, Gray , PENCE, Isaac J.
CPC分类号： A61B5/415 , A61B5/0071 , A61B5/0075 , A61B5/0086 , A61B5/418 , A61B5/4227 , A61B5/742 , A61B34/20 , A61B2034/2055 , A61B2505/05 , G01N21/6456 , G01N21/65 , G01N2021/6439 , G01N2201/0221
摘要： A process for intra-operatively providing anatomical guidance in an endocrine surgery, comprising: (a) illuminating human tissues in the neck area of a human being in operation with a beam of light; (b) obtaining fluorescence data from light emitted from the human tissues in response to the illumination; and (c) displaying images generated from the obtained fluorescence data in a display for providing anatomical guidance in the endocrine surgery.
摘要翻译： 一种用于在内分泌外科手术中提供解剖学指导的过程，包括：（a）用光束照射人体颈部区域中的人体组织; （b）响应于照射从人体组织发射的光获得荧光数据; 和（c）在显示器上显示从获得的荧光数据产生的图像，以提供内分泌手术中的解剖指导。
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公开(公告)号：EP3005941B1
公开(公告)日：2017-12-27
申请号：EP15187369.2
申请日：2009-07-30
发明人： MAHADEVAN-JANSEN, Anita , WHITE, Lisa , PHAY, John , PARAS, Constantine, A. , KANTER BARTZ, Elizabeth , KELLER, Matthew, D. , GASPARINO, Nicole , WHISENANT, Jennifer, Gray , PENCE, Isaac J.
CPC分类号： A61B5/415 , A61B5/0071 , A61B5/0075 , A61B5/0086 , A61B5/418 , A61B5/4227 , A61B5/742 , A61B34/20 , A61B2034/2055 , A61B2505/05 , G01N21/6456 , G01N21/65 , G01N2021/6439 , G01N2201/0221
摘要： A process for intra-operatively providing anatomical guidance in an endocrine surgery, comprising: (a) illuminating human tissues in the neck area of a human being in operation with a beam of light; (b) obtaining fluorescence data from light emitted from the human tissues in response to the illumination; and (c) displaying images generated from the obtained fluorescence data in a display for providing anatomical guidance in the endocrine surgery.
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公开(公告)号：EP4235157A3
公开(公告)日：2023-11-22
申请号：EP23181954.1
申请日：2009-07-30
发明人： MAHADEVAN-JANSEN, Anita , WHITE, Lisa , PHAY, John , PARAS, Constantine A. , KANTER BARTZ, Elizabeth , KELLER, Matthew D. , GASPARINO, Nicole , WHISENANT, Jennifer Gray , PENCE, Isaac J.
摘要： A system (400 A; C; E; G) for intra-operatively identifying parathyroid tissues and thyroid tissues of a living subject, comprising a light source (402) for illuminating tissues (407) in a target region in the neck area of the living subject, a light delivery and collection device (406, 426), which is optically coupled with the light source (402) for delivering a beam of light from the light source (402) to the tissue (407) and for collecting optical signals emitted from the tissue (407) responsive to the incident beam of light, and a detector (414, 434) for detecting the intensity of the optical signals emitted from the tissue (407) in order to enable a surgeon to differentiate between parathyroid tissues and thyroid tissues.
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公开(公告)号：EP2313000A1
公开(公告)日：2011-04-27
申请号：EP09803612.2
申请日：2009-07-30
发明人： MAHADEVAN-JANSEN, Anita , WHITE, Lisa , PHAY, John , PARAS, Constatine, A. , KANTER, Elizabeth , KELLER, Matthew, D. , GASPARINO, Nicole , WHISENANT, Jennifer, Gray
IPC分类号： A61B5/05
CPC分类号： A61B5/415 , A61B5/0071 , A61B5/0075 , A61B5/0086 , A61B5/418 , A61B5/4227 , A61B5/742 , A61B34/20 , A61B2034/2055 , A61B2505/05 , G01N21/6456 , G01N21/65 , G01N2021/6439 , G01N2201/0221
摘要： A method or process for intra-operatively providing anatomical guidance in endocrine surgery. In one embodiment, the process includes the steps of illuminating human tissues (407) in the neck area of a human being in operation with a beam of light (211, 454), obtaining fluorescent data from the light scattered (428, 405) from the human tissues, finding fluorescent signatures from the obtained fluorescent data, and identifying tissues that are corresponding to the fluorescent signatures that represent thyroid or parathyroid tissues.
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公开(公告)号：EP4110167A2
公开(公告)日：2023-01-04
申请号：EP21760645.8
申请日：2021-02-25
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公开(公告)号：EP3005941A3
公开(公告)日：2016-10-26
申请号：EP15187369.2
申请日：2009-07-30
发明人： MAHADEVAN-JANSEN, Anita , WHITE, Lisa , PHAY, John , PARAS, Constatine, A. , KANTER BARTZ, Elizabeth , KELLER, Matthew, D. , GASPARINO, Nicole , WHISENANT, Jennifer, Gray , PENCE, Isaac J.
CPC分类号： A61B5/415 , A61B5/0071 , A61B5/0075 , A61B5/0086 , A61B5/418 , A61B5/4227 , A61B5/742 , A61B34/20 , A61B2034/2055 , A61B2505/05 , G01N21/6456 , G01N21/65 , G01N2021/6439 , G01N2201/0221
摘要： A method or process for intra-operatively providing anatomical guidance in endocrine surgery. In one embodiment, the process includes the steps of illuminating human tissues (407) in the neck area of a human being in operation with a beam of light (211, 454), obtaining fluorescent data from the light scattered (428, 405) from the human tissues, finding fluorescent signatures from the obtained fluorescent data, and identifying tissues that are corresponding to the fluorescent signatures that represent thyroid or parathyroid tissues.
摘要翻译： 手术中提供内分泌手术解剖指导的方法或过程。 在一个实施例中，该过程包括以下步骤：利用光束（211,454）照射正在操作的人的颈部区域中的人体组织（407）;从散射的光（428,405）获得来自 人体组织，从获得的荧光数据中找到荧光标记，以及鉴定对应于代表甲状腺或甲状旁腺组织的荧光标记的组织。
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公开(公告)号：EP4442195A2
公开(公告)日：2024-10-09
申请号：EP24187913.9
申请日：2017-12-29
IPC分类号： A61B5/00
CPC分类号： A61B5/0066 , A61B5/0077 , A61B5/0261 , A61B5/415 , A61B2505/0520130101 , A61B90/361 , A61B90/30
摘要： One aspect of the invention relates to a method for intraoperative assessment of parathyroid gland viability in a surgery. The method includes diffusing a beam of light onto a tissue surface of a parathyroid gland of a patient to illuminate the tissue surface; acquiring images of the illuminated tissue surface, where each of the acquired images includes a speckle pattern; and processing the acquired images to obtain speckle contrast images for the intraoperative assessment of parathyroid gland viability.
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