公开(公告)号：EP3241837A1

公开(公告)日：2017-11-08

申请号：EP15874972.1

申请日：2015-11-11

申请人： Zhejiang Hisun Pharmaceutical Co., Ltd

发明人： GUO, Yanghui ,  ZHAO, Shiguo ,  ZHANG, Yue ,  ZHANG, Liang ,  YANG, Zhiqing ,  CHAI, Jian

IPC分类号： C07H19/10 ,  C07H1/06 ,  A61K31/7072 ,  A61P31/14

CPC分类号： C07H1/06 ,  C07H19/06 ,  C07H19/10

摘要： The present invention relates to a method for preparing Sofosbuvir crystal form-6. The method is simple in operation, stable in process condition, good in reproducibility, high in yield rate and high in purity, viscous gel-type products are not formed during the process, the problem of blocking of a discharge port is solved, and the method is suitable for mass industrial production and has high economic value.

摘要翻译： Sofosbuvir晶形-6的制备方法技术领域本发明涉及Sofosbuvir晶形-6的制备方法。 该方法操作简单，工艺条件稳定，重复性好，收率高，纯度高，在工艺过程中不形成粘性凝胶型产品，解决了出料口堵塞问题， 方法适用于大量工业生产，具有较高的经济价值。