公开(公告)号：EP2731654B1

公开(公告)日：2018-12-26

申请号：EP12811642.3

申请日：2012-07-11

Applicant: The Foundry, LLC

Inventor： MORRISS, John ,  GIFFORD, Hanson

IPC: A61M11/06 ,  A61M31/00 ,  A61K38/48 ,  A61M5/32 ,  A61M15/08 ,  A61M11/00

CPC classification number: A61M31/007 ,  A61K38/4893 ,  A61M5/329 ,  A61M11/001 ,  A61M11/007 ,  A61M11/06 ,  A61M15/08 ,  A61M15/085 ,  A61M16/0438 ,  A61M16/0456 ,  A61M16/0461 ,  A61M16/0481 ,  A61M31/002 ,  A61M2210/0618 ,  A61M2210/0681

Abstract: A system for delivering a therapeutic agent to nasopharyngeal mucosa tissue has a shaft, a porous pad of compliant material coupled to the shaft near the distal end, and a drug reservoir. The porous pad is configured to expand from a contracted configuration to an expanded configuration. The expanded configuration is adapted to engage and conform to the mucosa tissue in a nasal cavity, and the contracted configuration has a size suitable for introduction into the nasal cavity. The drug reservoir holds a therapeutic agent and is at least partially covered by the porous pad. The drug reservoir is configured to release a fixed volume of the therapeutic agent into the porous pad within a period of less than about 120 minutes, and has a wall with a plurality of channels fluidly coupled with the porous pad.

公开(公告)号：EP3195895A1

公开(公告)日：2017-07-26

申请号：EP17159646.3

申请日：2008-04-23

Applicant: Acclarent, Inc.

Inventor： GOLDFARB, Eric ,  CHANG, John, Y. ,  FACTEAU, William, M. ,  LAM, Sivette ,  HA, Hung, V. ,  KIM, Issac, J. ,  MUNI, Ketan, P.

IPC: A61M29/02 ,  A61M25/10 ,  A61M25/00

CPC classification number: A61M29/02 ,  A61M25/0041 ,  A61M25/0045 ,  A61M25/0662 ,  A61M25/09 ,  A61M25/10 ,  A61M25/1002 ,  A61M2025/0046 ,  A61M2025/0681 ,  A61M2025/1086 ,  A61M2029/025 ,  A61M2210/0618 ,  A61M2210/0681 ,  A61M2230/005

Abstract: A system for treating a disease or disorder of the ear, nose or throat of a human or animal subject, said system comprising a guide catheter (40c), a working catheter (10);
a guidewire (GW) and a member (61) that is attachable to the guidewire and limits the extent to which the guidewire is advanceable through the working catheter.

Abstract translation: 一种用于治疗人或动物受试者的耳朵，鼻子或咽喉疾病或病症的系统，所述系统包括引导导管（40c），工作导管（10）; 导丝（GW）和可附接到导丝并且限制导丝可通过工作导管推进的程度的构件（61）。

公开(公告)号：EP3189798A1

公开(公告)日：2017-07-12

申请号：EP15838306.7

申请日：2015-08-07

Applicant: Olympus Corporation

Inventor： FUJISAKI, Ken ,  ARAKI, Hiroyuki ,  YOSHIDA, Kazuhiro

IPC: A61B17/24

CPC classification number: A61B1/00154 ,  A61B1/00082 ,  A61B1/00094 ,  A61B1/00142 ,  A61B1/0016 ,  A61B1/00163 ,  A61B1/00172 ,  A61B1/015 ,  A61B1/05 ,  A61B1/07 ,  A61B1/233 ,  A61B17/24 ,  A61B17/3421 ,  A61B90/36 ,  A61B2017/00331 ,  A61B2017/00367 ,  A61B2017/0038 ,  A61B2017/00455 ,  A61B2017/0046 ,  A61B2017/00477 ,  A61B2017/00991 ,  A61B2017/22051 ,  A61B2017/246 ,  A61B2090/036 ,  A61B2090/0811 ,  A61B2090/306 ,  A61B2090/3614 ,  A61B2217/005 ,  A61M1/0064 ,  A61M2210/0681

Abstract: An endoscopic treatment instrument includes a guide pipe and a guide sheath. The guide pipe through which the insertion portion is inserted so that a distal side of a distal end of the insertion portion and a distal side of a first distal end are observable through the first distal end by the observation optical system of an endoscope or so that the distal side of the distal end of the insertion portion is observable by the observation optical system while the distal end of the insertion portion is protruded relative to the first distal end. The guide sheath has an inside diameter to insert the insertion portion therethrough so that the distal end of the insertion portion is configured to protrude relative to the second distal end and is inserted through the guide pipe so that the second distal end is configured to protrude relative to the first distal end of the guide pipe.

Abstract translation: 内窥镜处理器具包括导管和引导护套。 插入部插入的导管通过内窥镜的观察光学系统能够通过第一前端观察插入部的前端的前端侧和第一前端的前端侧，或者， 当插入部分的远端相对于第一远端突出时，插入部分的远端的远侧可被观察光学系统观察到。 引导护套具有内径以插入插入部分，从而插入部分的远端构造成相对于第二远端突出并且插入穿过引导管，使得第二远端构造成相对突出 到导管的第一远端。

公开(公告)号：EP3188780A1

公开(公告)日：2017-07-12

申请号：EP15788103.8

申请日：2015-09-01

Applicant: Université François-Rabelais de Tours

Inventor： FRANCIS, Mirvatte ,  VECELLIO-NONE, Laurent

IPC: A61M11/08 ,  A61M15/00

CPC classification number: A61M15/08 ,  A61M11/001 ,  A61M11/005 ,  A61M11/007 ,  A61M11/08 ,  A61M15/002 ,  A61M15/0065 ,  A61M15/009 ,  A61M15/0091 ,  A61M15/0098 ,  A61M2202/064 ,  A61M2205/071 ,  A61M2205/073 ,  A61M2210/0681

Abstract: Device (100) for nasal spraying of fluid product, having a reservoir (10) containing at least one dose of fluid product, a dispensing system (20) for spraying a dose (D) of product through a spray orifice (35) each time the device is actuated, thus generating a spray that extends axially from said spray orifice (35), said device (100) comprising a system (40) for generating a secondary flow, actuated at the same time as said dispensing system (20), said system (40) for generating a secondary flow having a secondary flow channel (41) provided with an outlet orifice (45), said outlet orifice (45) being arranged downstream from said spray orifice (35) in the axial direction of said spray, and said secondary flow extending from said outlet orifice (45) along an axis (B) forming an angle (α) with respect to the axis (A) of said spray and intersecting said axis (A), in order thereby to deform and/or divert said spray.

Abstract translation: 用于鼻腔喷雾流体产品的装置（100），具有包含至少一个剂量的流体产品的贮存器（10），用于每次通过喷射孔（35）喷射剂量（D）的产品的分配系统（20） 所述装置被致动，从而产生从所述喷射孔（35）轴向延伸的喷雾，所述装置（100）包括用于产生与所述分配系统（20）同时被致动的辅助流的系统（40） 所述系统（40）用于产生具有设置有出口孔（45）的第二流动通道（41）的第二流动，所述出口孔（45）在所述喷射器的轴向方向上布置在所述喷射孔口（35）的下游 ，并且所述二次流从所述出口孔（45）沿着相对于所述喷雾的轴线（A）与所述轴线（A）相交形成角度（α）的轴线（B）延伸，以便由此变形并且 /或转移所述喷雾。

公开(公告)号：EP3185786A1

公开(公告)日：2017-07-05

申请号：EP15754346.3

申请日：2015-08-11

Applicant: Acclarent, Inc.

Inventor： KESTEN, Randy J. ,  LIN, Arthur M. ,  CHAMNESS, Scott O.

IPC: A61B17/24 ,  A61M25/00 ,  A61M29/02

CPC classification number: A61M25/10182 ,  A61B17/24 ,  A61M3/0295 ,  A61M5/31511 ,  A61M5/31575 ,  A61M25/0097 ,  A61M25/10184 ,  A61M29/00 ,  A61M29/02 ,  A61M2210/0681

Abstract: An inflator comprises a body, a first drive member, and a second drive member. The body defines a reservoir that is configured to hold fluid and includes an outlet. The first drive member is operable to move through the reservoir to drive fluid from the reservoir through the outlet. The second drive member is engaged with the first drive member. The second drive member is movable relative to the body through a first range of motion to actuate the first drive member to drive fluid through the outlet at a first rate. The second drive member is movable relative to the body through a second range of motion following the second range of motion. The first drive member is configured to either drive fluid through the outlet at a second rate or not drive fluid through the outlet as the second drive member moves through the second range of motion.

Abstract translation: 充气机包括主体，第一驱动构件和第二驱动构件。 主体限定配置成容纳流体并包括出口的储存器。 第一驱动构件可操作以移动通过储存器以通过出口从储存器驱动流体。 第二驱动构件与第一驱动构件接合。 第二驱动构件可通过第一运动范围相对于本体移动以致动第一驱动构件以第一速率驱动流体通过出口。 第二驱动构件能够在第二运动范围之后通过第二运动范围相对于本体运动。 第一驱动构件构造成当第二驱动构件移动通过第二运动范围时以第二速率驱动流体通过出口或者不驱动流体通过出口。

公开(公告)号：EP2185234B1

公开(公告)日：2017-03-08

申请号：EP08746715.5

申请日：2008-04-23

Applicant: Acclarent, Inc.

Inventor： GOLDFARB, Eric ,  CHANG, John, Y. ,  FACTEAU, William, M. ,  LAM, Sivette ,  HA, Hung, V. ,  KIM, Issac, J. ,  MUNI, Ketan, P.

IPC: A61M29/02 ,  A61M25/00 ,  A61M25/10

CPC classification number: A61M29/02 ,  A61M25/0041 ,  A61M25/0045 ,  A61M25/0662 ,  A61M25/09 ,  A61M25/10 ,  A61M25/1002 ,  A61M2025/0046 ,  A61M2025/0681 ,  A61M2025/1086 ,  A61M2029/025 ,  A61M2210/0618 ,  A61M2210/0681 ,  A61M2230/005

Abstract: A system for treating a disease or disorder of the ear, nose or throat of a human or animal subject, said system comprising a guide catheter (40c), a working catheter (10); a guidewire (GW) and a member (61) that is attachable to the guidewire and limits the extent to which the guidewire is advanceable through the working catheter.

Abstract translation: 可用于扩张鼻窦口和/或耳，鼻或咽喉内其他通道的口腔的装置，系统和方法。 膨胀导管装置和系统以促进操作者易于使用的方式构造，并且在至少一些情况下允许扩张程序由单个操作者执行。 此外，扩张导管装置和系统可以与内窥镜和/或荧光镜结合使用以提供装置的简单操作和定位以及整个程序或其选定部分的实时可视化。 在一些实施例中，可以使用可选的手柄来便于用单手抓握或支撑本发明的装置以及另一装置（例如，内窥镜）。

公开(公告)号：EP2285436B1

公开(公告)日：2015-10-28

申请号：EP09739379.7

申请日：2009-04-02

Applicant: Medtronic Xomed, Inc.

Inventor： PRISCO, John, R. ,  SLENKER, Dale, E. ,  PERRY, Isaac, C.

IPC: A61M3/02

CPC classification number: A61M3/0279 ,  A61B1/233 ,  A61M3/0216 ,  A61M3/0233 ,  A61M3/025 ,  A61M3/0258 ,  A61M31/00 ,  A61M2206/16 ,  A61M2210/0618 ,  A61M2210/0681

Abstract: A surgical instrument for irrigating a frontal sinus target site of a patient including a handle, an introducer, an irrigation channel, a nozzle, and an actuator assembly. The introducer extends from the handle and defines a proximal segment and a distal segment. At least a portion of the proximal segment is linear and at least a portion of the distal segment is relatively curved. The nozzle is fluidly connected to the irrigation channel, and is rotatably maintained at a distal end of the introducer. The actuator assembly includes an actuator maintained by the handle and connected to the nozzle. Movement of the actuator causes the nozzle to rotate relative to the introducer. The introducer can be sized and shaped in accordance with a size and a shape of a nasal passageway/frontal sinus of a human adult.

公开(公告)号：EP2836170A1

公开(公告)日：2015-02-18

申请号：EP13775257.2

申请日：2013-03-28

Applicant: Sinopsys Surgical, Inc.

Inventor： ROSS, Harry ,  WILLOUGHBY, Brian James ,  OLIVER, Christopher Lee ,  SCHOMER, Donald F. ,  CIMINO, William W.

IPC: A61F2/76 ,  A61F2/74 ,  A61M31/00

CPC classification number: A61M27/002 ,  A61B17/3468 ,  A61F9/00772 ,  A61M29/00 ,  A61M2210/0681

Abstract: An implant device to provide an artificial fluid path in fluid communication with the lacrimal apparatus is implanted through a fistula opening into the lacrimal apparatus using a working member disposed through the implant device and a break-away sheath. Implantation kits and tool assemblies including the working member, implant device and break-away sheath facilitate implantation of the implant device.

公开(公告)号：EP2731654A1

公开(公告)日：2014-05-21

申请号：EP12811642.3

申请日：2012-07-11

Applicant: The Foundry, LLC

Inventor： MORRISS, John ,  GIFFORD, Hanson

IPC: A61M11/06

CPC classification number: A61M31/007 ,  A61K38/4893 ,  A61M5/329 ,  A61M11/001 ,  A61M11/007 ,  A61M11/06 ,  A61M15/08 ,  A61M15/085 ,  A61M16/0438 ,  A61M16/0456 ,  A61M16/0461 ,  A61M16/0481 ,  A61M31/002 ,  A61M2210/0618 ,  A61M2210/0681

Abstract: A system for delivering a therapeutic agent to nasopharyngeal mucosa tissue has a shaft, a porous pad of compliant material coupled to the shaft near the distal end, and a drug reservoir. The porous pad is configured to expand from a contracted configuration to an expanded configuration. The expanded configuration is adapted to engage and conform to the mucosa tissue in a nasal cavity, and the contracted configuration has a size suitable for introduction into the nasal cavity. The drug reservoir holds a therapeutic agent and is at least partially covered by the porous pad. The drug reservoir is configured to release a fixed volume of the therapeutic agent into the porous pad within a period of less than about 120 minutes, and has a wall with a plurality of channels fluidly coupled with the porous pad.

Abstract translation: 用于将治疗剂递送到鼻咽粘膜组织的系统具有轴，连接到靠近远端的轴的顺应性材料的多孔垫和药物储存器。 多孔垫被构造成从收缩构型扩展到扩展构型。 膨胀的构造适于与鼻腔中的粘膜组织接合并顺应，并且收缩构造具有适于引入鼻腔的尺寸。 药物储存器保持治疗剂并且至少部分被多孔垫覆盖。 药物储存器构造成在小于约120分钟的时间内将固定体积的治疗剂释放到多孔垫中，并且具有多个通道与多孔垫流体耦合的壁。 [

公开(公告)号：EP2662109A1

公开(公告)日：2013-11-13

申请号：EP13179223.6

申请日：2005-09-14

Applicant: Acclarent, Inc.

Inventor： Chang, John Y. ,  Makower, Joshua ,  Vrany, Julia D. ,  Walke, Amrish, Jayprakash

IPC: A61M29/00 ,  A61M25/10 ,  A61B17/24

CPC classification number: A61M29/02 ,  A61B5/6852 ,  A61B17/24 ,  A61B17/32002 ,  A61B17/3403 ,  A61B17/3421 ,  A61B18/1492 ,  A61B2017/22039 ,  A61B2017/22051 ,  A61B2017/22061 ,  A61B2018/00327 ,  A61B2018/00595 ,  A61B2034/2051 ,  A61F2/186 ,  A61F2/82 ,  A61F2/90 ,  A61F2/95 ,  A61F2/958 ,  A61M25/0026 ,  A61M25/005 ,  A61M25/0082 ,  A61M25/0102 ,  A61M25/0138 ,  A61M25/0147 ,  A61M25/09 ,  A61M25/10 ,  A61M25/1006 ,  A61M25/1011 ,  A61M2025/0177 ,  A61M2025/1072 ,  A61M2025/1079 ,  A61M2025/109 ,  A61M2029/025 ,  A61M2210/0681 ,  A61M2210/1028

Abstract: A guide catheter (200) has a pre-set shape for insertion into a nasal cavity. Said guide catheter (200) comprises a proximal end, a distal end, and a lumen extending from the proximal end to the distal end. Said guide catheter (200) incorporates one or more preformed curves or bends, wherein the curved or bent regions form a deflection angle selected from: 30 degrees, 45 degrees, 60 degrees, 70 degrees, 90 degrees, 120 degrees and 135 degrees.
A system for diagnosing and/or treating sinusitis or another disorder affecting the nose, paranasal sinuses or other anatomical structures of the ear, nose or throat comprises: a guide catheter (200) as described above; a balloon catheter (204) that can be advanced along the guide catheter (200), wherein the balloon catheter (204) comprises an inflatable balloon; and optionally a guidewire (202) that can be inserted through the lumen of the guide catheter (200).

Abstract translation: 引导导管（200）具有预先设定的形状，用于插入到鼻腔中。 所述引导导管（200）包括一个近端，一个远端，以及一个从管腔近端到远端延伸。 所述引导导管（200）包括一个或多个预制的曲线或弯曲，worin的弯曲或弯折的区域形成选自以下的偏转角：30度，45度，60度，70度，90度，120度和135度。 一种用于诊断和/或治疗鼻窦炎或另一种病症影响鼻部的系统，鼻旁窦或耳，鼻或咽喉其他解剖结构包括：如上所述的引导导管（200）; 球囊导管（204）确实可以沿导向导管（200）worin气囊导管（204）可充气气囊的包括前进; 和任选的（202）做了导丝可以穿过导​​向导管（200）的内腔插入。