PRESSURE LIMITING MECHANISM FOR FLUID DISPLACEMENT AND PRESSURIZING SYRINGE

    公开(公告)号:EP3120891B1

    公开(公告)日:2018-11-28

    申请号:EP16179740.2

    申请日:2016-07-15

    IPC分类号: A61M25/10 A61M39/22 A61M5/48

    摘要: A syringe which has an intended pressure limit. The syringe includes a syringe body (12), and a pressure-limiting mechanism is disposed inside the syringe body. The pressure-limiting mechanism comprises a valve assembly (18) including a valve spool (66) which is spring biased in the syringe body. In one embodiment, the pressure-limiting mechanism is provided in the form of a valve seal (88) included in a valve piston (84) provided on the valve spool (66) which moves into sealing engagement with an internal wall (92) of a valve bore in the syringe housing once the intended pressure limit is reached. In another embodiment, the pressure-limiting mechanism is provided in the form of the valve mechanism (110) having a valve seat (138) on the distal end of a valve spool (114) which moves into sealing or plugged engagement with a valve plug (142) once the intended pressure limit is reached. Regardless of the exact configuration, preferably the syringe is simple, reliable, easy to assembly, and easy to sterilize given its low number of parts.

    REINFORCED SYRINGE BODY
    3.
    发明公开
    REINFORCED SYRINGE BODY 审中-公开
    加强的注射器身体

    公开(公告)号:EP3319678A1

    公开(公告)日:2018-05-16

    申请号:EP16821894.9

    申请日:2016-07-06

    IPC分类号: A61M25/10 A61M5/31 A61M5/48

    CPC分类号: A61M25/10182

    摘要: A syringe body is disclosed, wherein the syringe body is configured to withstand pressures within a fluid reservoir of the syringe body of between about 0 atmospheres (atm) and about 81 atm and/or between about 0 atm and about 109 atm. The syringe body may be configured for use in connection with an inflation device. The syringe body may comprise one or more stiffening ribs and/or a stiffening lip. Methods of using the syringe body in connection with an inflation device are also disclosed.

    BALLOON CATHETER SYSTEMS FOR DELIVERY OF DRY DRUG DELIVERY VESICLES TO A VESSEL IN THE BODY
    8.
    发明公开
    BALLOON CATHETER SYSTEMS FOR DELIVERY OF DRY DRUG DELIVERY VESICLES TO A VESSEL IN THE BODY 审中-公开
    巴伦火山系统ZUR FREISETZUNG VON TROCKENWIRKSTOFFFREISETZUNGSVESIKELN IN EINEMGEFÄSSDESKÖRPERS

    公开(公告)号:EP2603274A4

    公开(公告)日:2017-07-19

    申请号:EP10841767

    申请日:2010-12-30

    摘要: Devices and methods for balloon delivery of rapamycin and other hydrophobic compounds to the wall of blood vessels. Balloon catheters, such as those used for balloon angioplasty, are modified with the addition of a reservoir of dry micelles, disposed at a suitable location within the balloon or catheter. The reservoir may be installed within the angioplasty balloon, within a lumen in communication with the angioplasty balloon, either as a loose or packed powder or as a film coating. The micelle preparation is reconstituted and the micelles are mobilized when the aqueous solution used to inflate the balloons is injected into the catheter. The micelles are infused into tissue surrounding the balloon when pressurized fluid within the balloon leaks through the wall of the balloon.

    摘要翻译: 用于将雷帕霉素和其他疏水性化合物球囊递送至血管壁的装置和方法。 球囊导管,例如用于球囊血管成形术的球囊导管,通过添加储存器的干胶束而被改进,所述干胶束储存在球囊或导管内的合适位置。 储存器可以安装在血管成形术球囊内,在与血管成形术球囊连通的腔内,作为松散的或填充的粉末或作为膜涂层。 当用于使气球充气的水溶液被注入导管时,胶束制剂被重构并且胶束被移动。 当气囊内的加压流体通过气囊壁泄漏时,胶束被注入到气囊周围的组织中。