公开(公告)号：EP2263738A3

公开(公告)日：2011-11-09

申请号：EP10182893.7

申请日：2005-07-18

Applicant: Acclarent, Inc.

Inventor： Makower, Joshua ,  Chang, John Y ,  Vrany, Julia D ,  Walke, Amrish, Jayprakash

IPC: A61M29/00 ,  A61K9/22 ,  A61B19/00 ,  A61M25/10 ,  A61F5/08 ,  A61B17/24 ,  A61B5/06 ,  A61B17/16 ,  A61B1/00

CPC classification number: A61M31/002 ,  A61B5/06 ,  A61B5/064 ,  A61B5/411 ,  A61B17/24 ,  A61B17/320725 ,  A61B17/320758 ,  A61B17/320783 ,  A61B17/3478 ,  A61B34/20 ,  A61B2017/22061 ,  A61F2/18 ,  A61F2/82 ,  A61F2002/825 ,  A61F2250/0039 ,  A61M25/0029 ,  A61M25/007 ,  A61M25/10 ,  A61M2025/0037 ,  A61M2025/105 ,  A61M2025/1052

Abstract: Implantable devices for delivering drugs and other substances to locations within the body of a human or animal subject to treat or diagnose sinusitis and a variety of other disorders. The application includes implantable substance delivery devices that comprise reservoirs and barriers that control the rate at which substances pass out of the reservoirs. The delivery devices may be advanced into the body using guidewires, catheters, ports, introducers and other access apparatus. In some embodiments the delivery devices may be loaded with one or more desired substance before their introduction into the body. In other embodiments the delivery devices are loaded and/or reloaded with a desired substance after the delivery device has been introduced into the body.

公开(公告)号：EP1857071A3

公开(公告)日：2008-05-07

申请号：EP07252018.2

申请日：2007-05-16

Applicant: Acclarent, Inc.

Inventor： Kim, Isaac J. ,  Foldarb, Eric ,  Muni, Ketan P. ,  Makower, Joshua ,  Deckman, Robert K.

IPC: A61B19/00

CPC classification number: A61B17/3415 ,  A61B1/313 ,  A61B6/12 ,  A61B6/485 ,  A61B90/39 ,  A61B90/50 ,  A61B90/94 ,  A61B2017/00292 ,  A61B2017/3407 ,  A61B2017/3486 ,  A61B2034/2051 ,  A61B2090/3958 ,  A61B2090/397 ,  A61B2090/3975 ,  A61B2090/3983

Abstract: Devices and methods wherein an adapter (10) is used to attach an electromagnetic image guidance component (12) to a medical device (14) such that an electromagnetic image guidance system may be used to track the location of the medical device within the body of a human or animal subject.

公开(公告)号：EP2959865A1

公开(公告)日：2015-12-30

申请号：EP15163549.7

申请日：2005-09-14

Applicant: Acclarent, Inc.

Inventor： Chang, John Y. ,  Makower, Joshua ,  Vrany, Julia D. ,  Walke, Amrish, Jayprakash

IPC: A61F2/18 ,  A61B5/00 ,  A61B17/24 ,  A61B17/32 ,  A61F2/82 ,  A61F2/90 ,  A61B17/34 ,  A61F2/95 ,  A61M25/00 ,  A61M25/01 ,  A61M25/09 ,  A61M25/10 ,  A61F2/958 ,  A61B18/14 ,  A61M29/02 ,  A61B17/22 ,  A61B18/00 ,  A61B19/00

CPC classification number: A61M29/02 ,  A61B5/6852 ,  A61B17/24 ,  A61B17/32002 ,  A61B17/3403 ,  A61B17/3421 ,  A61B18/1492 ,  A61B2017/22039 ,  A61B2017/22051 ,  A61B2017/22061 ,  A61B2018/00327 ,  A61B2018/00595 ,  A61B2034/2051 ,  A61F2/186 ,  A61F2/82 ,  A61F2/90 ,  A61F2/95 ,  A61F2/958 ,  A61M25/0026 ,  A61M25/005 ,  A61M25/0082 ,  A61M25/0102 ,  A61M25/0138 ,  A61M25/0147 ,  A61M25/09 ,  A61M25/10 ,  A61M25/1006 ,  A61M25/1011 ,  A61M2025/0177 ,  A61M2025/1072 ,  A61M2025/1079 ,  A61M2025/109 ,  A61M2029/025 ,  A61M2210/0681 ,  A61M2210/1028

Abstract: Sinusitis and other disorders of the ear, nose and throat are diagnosed and/or treated using minimally invasive approaches with flexible or rigid instruments. Various methods and devices are used for remodelling or changing the shape, size or configuration of a sinus ostium or duct or other anatomical structure in the ear, nose or throat; implanting a device, cells or tissues; removing matter from the ear, nose or throat; delivering diagnostic or therapeutic substances or performing other diagnostic or therapeutic procedures. Introducing devices may be used, comprising a introducing member having a proximal end and a distal end for insertion into in a nasal cavity; and a working device that can be advanced along the introducing member, wherein the working device comprises a balloon catheter comprises radiographic markers.

Abstract translation: 鼻窦炎和耳，鼻，喉的其它病症被诊断和/或使用具有柔性或刚性的乐器微创治疗途径。 各种方法和装置用于重塑或改变在耳，鼻或咽喉鼻窦口或导管或其他解剖结构的形状，尺寸或构型; 植入装置，细胞或组织; 从耳，鼻或喉咙移除事宜; 递送诊断或治疗物质或进行其它诊断或治疗过程。 引入装置可以被使用，包括：具有近端和远端用于插入到鼻腔中一个导入部件; 和工作装置都可以沿着导入部件worin工作设备包括球囊导管包括射线照相标记前进。

公开(公告)号：EP2258440B1

公开(公告)日：2014-08-20

申请号：EP10182961.2

申请日：2005-07-18

Applicant: Acclarent, Inc.

Inventor： Chang, John Y ,  Makower, Joshua ,  Vrany, Julia D ,  Walke, Amrish, Jayprakash

IPC: A61F2/18 ,  A61F2/82 ,  A61B17/3207 ,  A61B17/34 ,  A61B5/00 ,  A61M25/00 ,  A61M31/00 ,  A61B17/22 ,  A61B5/06 ,  A61M25/10 ,  A61B17/24 ,  A61B19/00

CPC classification number: A61M31/002 ,  A61B5/06 ,  A61B5/064 ,  A61B5/411 ,  A61B17/24 ,  A61B17/320725 ,  A61B17/320758 ,  A61B17/320783 ,  A61B17/3478 ,  A61B34/20 ,  A61B2017/22061 ,  A61F2/18 ,  A61F2/82 ,  A61F2002/825 ,  A61F2250/0039 ,  A61M25/0029 ,  A61M25/007 ,  A61M25/10 ,  A61M2025/0037 ,  A61M2025/105 ,  A61M2025/1052

公开(公告)号：EP2638871A1

公开(公告)日：2013-09-18

申请号：EP13172140.9

申请日：2005-04-21

Applicant: Acclarent, Inc.

Inventor： Makower, Joshua ,  Chang, John Y.

IPC: A61B17/32 ,  A61B17/24

CPC classification number: A61B17/24 ,  A61B1/233 ,  A61B1/313 ,  A61B10/0233 ,  A61B10/06 ,  A61B17/0218 ,  A61B17/1688 ,  A61B17/29 ,  A61B17/3201 ,  A61B17/32053 ,  A61B17/32056 ,  A61B17/320725 ,  A61B17/320758 ,  A61B17/320783 ,  A61B17/3478 ,  A61B18/02 ,  A61B18/042 ,  A61B18/12 ,  A61B18/18 ,  A61B2017/00477 ,  A61B2017/22061 ,  A61B2017/320052 ,  A61B2017/320064 ,  A61B2018/00327 ,  A61B2018/00595 ,  A61B2018/0212 ,  A61B2018/1405 ,  A61B2217/005 ,  A61B2217/007 ,  A61F2/18 ,  A61F2/186 ,  A61F2/82 ,  A61F11/004 ,  A61F13/2005 ,  A61F2250/0039 ,  A61M16/0434 ,  A61M25/10 ,  A61M29/02 ,  A61M31/00 ,  A61M31/005 ,  A61N1/0541

Abstract: A device (700, 714, 714', 820) for removing polyps or other tissue from the nose, nasopharynx or paranasal sinus, said device comprising:a flexible catheter (702, 718, 822) having a distal end and a lumen; a flexible tube (704, 722, 830) having an open distal end and a lumen extending therethrough, said flexible tube (704, 722, 830) being rotatably disposed within a lumen of the catheter (702, 718, 822) such that the flexible tube (704, 722, 830) may rotate while the catheter (702, 718, 822) does not rotate; a rotating cutter (706, 724, 832) on the distal end of the flexible tube (704, 722, 830); and an opening formed in the catheter (702, 718, 822) such that matter may be received through the opening and cut by the rotating cutter (706, 724, 832).
Systems comprising the device are also disclosed.

Abstract translation: 一种用于从鼻子，鼻咽或鼻旁窦去除息肉或其他组织的装置（700，714，714”，820），所述装置包括：具有远端和内腔的柔性导管（702，718，822）; 柔性管（704，722，830），其具有开口远端和内腔延伸穿过那里，所述柔性管（704，722，830）可旋转地在导管的管腔内设置（702，718，822）检测DASS死 柔性管（704，722，830）可旋转，而导管（702，718，822）不旋转; 在挠性管（704，722，830）的远端上的旋转刀具（706，724，832）; 和在导管开口部（702，718，822）研究这个问题可通过开口被接收，并通过旋转刀具（706，724，832）切断。 该设备包括系统非常游离缺失盘。

公开(公告)号：EP2535079A3

公开(公告)日：2013-02-13

申请号：EP12183000.4

申请日：2006-01-18

Applicant: Acclarent, Inc.

Inventor： Chang, John Y. ,  Makower, Joshua ,  Vrany, Julia D. ,  Lamson, Theodore, C. ,  Walke, Amrish, Jayprakash

IPC: A61M29/02 ,  A61B1/233

CPC classification number: A61B1/00154 ,  A61B1/233 ,  A61B5/062 ,  A61B5/745 ,  A61B17/1204 ,  A61B17/12045 ,  A61B17/12104 ,  A61B17/12136 ,  A61B17/24 ,  A61B18/24 ,  A61B50/13 ,  A61B50/15 ,  A61B50/20 ,  A61F11/00 ,  A61F11/002 ,  A61M25/0041 ,  A61M25/1002 ,  A61M25/1011 ,  A61M29/02 ,  A61M2025/0226 ,  A61M2025/0681 ,  A61M2025/09116 ,  A61M2025/09175 ,  A61M2025/105 ,  A61M2025/1052 ,  A61M2210/0675 ,  A61N7/022

Abstract: A device for lavage of a paranasal sinus having an ostium, said device comprising: a catheter (1800,1900) having a proximal end, a distal end, an infusion lumen (1812,1902), an aspiration lumen (1810,1914), an infusion outlet aperture (1806,1904) and an aspiration inlet aperture (1808); and a balloon (1804,1912) for occluding a paranasal sinus ostium located on the catheter proximal to the infusion fluid outlet aperture and aspiration inlet aperture, whereby lavage fluid may be infused through the infusion lumen, out of the infusion outlet aperture and into the paranasal sinus and such lavage fluid may then be aspirated from the paranasal sinus through the aspiration inlet aperture and through the aspiration lumen.

公开(公告)号：EP2532300A3

公开(公告)日：2013-01-16

申请号：EP12182998.0

申请日：2006-01-18

Applicant: Acclarent, Inc.

Inventor： Chang, John Y. ,  Makower, Joshua ,  Vrany, Julia D. ,  Lamson, Theodore, C. ,  Walke, Amrish, Jayprakash

IPC: A61B1/233 ,  A61M29/02

CPC classification number: A61B1/00154 ,  A61B1/233 ,  A61B5/062 ,  A61B5/745 ,  A61B17/1204 ,  A61B17/12045 ,  A61B17/12104 ,  A61B17/12136 ,  A61B17/24 ,  A61B18/24 ,  A61B50/13 ,  A61B50/15 ,  A61B50/20 ,  A61F11/00 ,  A61F11/002 ,  A61M25/0041 ,  A61M25/1002 ,  A61M25/1011 ,  A61M29/02 ,  A61M2025/0226 ,  A61M2025/0681 ,  A61M2025/09116 ,  A61M2025/09175 ,  A61M2025/105 ,  A61M2025/1052 ,  A61M2210/0675 ,  A61N7/022

Abstract: A device (900) for insertion into a paranasal sinus, Eustachian tube, naso- lacrimal duct or other anatomical structure of the ear, nose or throat and for guiding a second device to that paranasal sinus, Eustachian tube, naso-lacrimal duct or other anatomical structure, said device comprising: an elongate shaft (902) having a proximal end and a distal end, at least a portion of said shaft being formed of plastically deformable material such that it may be bent into a desired shape; a bulbous tip member (906) on the distal end of the shaft; and a handle (904) attached to the proximal end of the shaft. Suitably, the handle (904) is detachable from said proximal end of the shaft. Also provided is a system comprising a device (900) according to the invention in combination with a second device that is advanceable over the shaft (902) when the handle (904) is detached from the proximal end of the shaft.

公开(公告)号：EP1857071A2

公开(公告)日：2007-11-21

申请号：EP07252018.2

申请日：2007-05-16

Applicant: Acclarent, Inc.

Inventor： Kim, Isaac J. ,  Foldarb, Eric ,  Muni, Ketan P. ,  Makower, Joshua ,  Deckman, Robert K.

IPC: A61B19/00

CPC classification number: A61B17/3415 ,  A61B1/313 ,  A61B6/12 ,  A61B6/485 ,  A61B90/39 ,  A61B90/50 ,  A61B90/94 ,  A61B2017/00292 ,  A61B2017/3407 ,  A61B2017/3486 ,  A61B2034/2051 ,  A61B2090/3958 ,  A61B2090/397 ,  A61B2090/3975 ,  A61B2090/3983

Abstract: Devices and methods wherein an adapter (10) is used to attach an electromagnetic image guidance component (12) to a medical device (14) such that an electromagnetic image guidance system may be used to track the location of the medical device within the body of a human or animal subject.

Abstract translation: 适配器的装置和方法worin（10）用于连接到电磁图像引导部件（12）一种医疗器械（14）检测并给电磁图像引导系统可以用于体内跟踪医疗装置的位置 一个人或动物受试者。

公开(公告)号：EP2662109B1

公开(公告)日：2015-04-15

申请号：EP13179223.6

申请日：2005-09-14

Applicant: Acclarent, Inc.

Inventor： Chang, John Y. ,  Makower, Joshua ,  Vrany, Julia D. ,  Walke, Amrish, Jayprakash

IPC: A61M29/00 ,  A61M25/10 ,  A61B17/24

CPC classification number: A61M29/02 ,  A61B5/6852 ,  A61B17/24 ,  A61B17/32002 ,  A61B17/3403 ,  A61B17/3421 ,  A61B18/1492 ,  A61B2017/22039 ,  A61B2017/22051 ,  A61B2017/22061 ,  A61B2018/00327 ,  A61B2018/00595 ,  A61B2034/2051 ,  A61F2/186 ,  A61F2/82 ,  A61F2/90 ,  A61F2/95 ,  A61F2/958 ,  A61M25/0026 ,  A61M25/005 ,  A61M25/0082 ,  A61M25/0102 ,  A61M25/0138 ,  A61M25/0147 ,  A61M25/09 ,  A61M25/10 ,  A61M25/1006 ,  A61M25/1011 ,  A61M2025/0177 ,  A61M2025/1072 ,  A61M2025/1079 ,  A61M2025/109 ,  A61M2029/025 ,  A61M2210/0681 ,  A61M2210/1028

Abstract: A guide catheter (200) has a pre-set shape for insertion into a nasal cavity. Said guide catheter (200) comprises a proximal end, a distal end, and a lumen extending from the proximal end to the distal end. Said guide catheter (200) incorporates one or more preformed curves or bends, wherein the curved or bent regions form a deflection angle selected from: 30 degrees, 45 degrees, 60 degrees, 70 degrees, 90 degrees, 120 degrees and 135 degrees. A system for diagnosing and/or treating sinusitis or another disorder affecting the nose, paranasal sinuses or other anatomical structures of the ear, nose or throat comprises: a guide catheter (200) as described above; a balloon catheter (204) that can be advanced along the guide catheter (200), wherein the balloon catheter (204) comprises an inflatable balloon; and optionally a guidewire (202) that can be inserted through the lumen of the guide catheter (200).

公开(公告)号：EP2845621A3

公开(公告)日：2015-04-08

申请号：EP14181385.7

申请日：2005-07-18

Applicant: Acclarent, Inc.

Inventor： Chang, John Y. ,  Makower, Joshua ,  Vrany, Julia D ,  Walke, Amrish Jayprakash

IPC: A61M29/00 ,  A61K9/22 ,  A61B19/00 ,  A61B17/24 ,  A61M25/10 ,  A61B5/06 ,  A61F2/18 ,  A61F2/82 ,  A61B17/3207 ,  A61B17/34 ,  A61B5/00 ,  A61M25/00 ,  A61M31/00 ,  A61B17/22

Abstract: The present application relates generally to medical systems and more particularly to substance delivering implants for treating a broad range of disorders including but not limited to sinusitis and other ear, nose and throat disorders. The system includes a guide catheter for insertion into the nose and a balloon catheter comprising a balloon. The balloon catheter is advanceable through the guide catheter to a location where the balloon is within the Eustachian tube and inflatable to enlarge the Eustachian tube. It is thereafter removable leaving the guide catheter in place. The system also includes a device for delivering a substance to a location within the body of a human or animal subject to diagnose or treat a disorder. The device includes a reservoir that may be loaded with the substance and a barrier located in relation to the reservoir such that substance that has been loaded into the reservoir will pass out of the reservoir and through the barrier at a known rate. A delivery catheter is advanceable through the guide catheter into the Eustachian tube and useable to deliver the implantable substance delivery device to the enlarged Eustachian tube.