公开(公告)号：EP3253732A1

公开(公告)日：2017-12-13

申请号：EP16747315.6

申请日：2016-02-05

申请人： Cempra Pharmaceuticals, Inc.

发明人： SCHNEIDER, Stephen E. ,  PEREIRA, David Eugene

IPC分类号： C07C247/04

CPC分类号： C07C247/04 ,  C07C53/06 ,  C07C53/10 ,  C07C53/122 ,  C07C53/124 ,  C07C53/18 ,  C07C55/07 ,  C07C55/08 ,  C07C57/145 ,  C07C57/15 ,  C07C59/08 ,  C07C59/19 ,  C07C59/255 ,  C07C59/265 ,  C07C63/08 ,  C07C309/04 ,  C07C309/30

摘要： Neat 4-azidobutylamine and sails of 4-azidobutylamine and processes for producing the same are described herein. Amines represent a large class of organic compounds containing a basic nitrogen atom having a lone pair of electrons and one or more substituent groups. Many amines are used as precursors and feedstocks in a wide variety of industries such as textiles, agriculture, plastics, and pharmaceuticals. One such amine is 4-azidobutylamine, N3-(CH2)4NH2, an amine of butane that also includes an azide.

公开(公告)号：EP2266585B1

公开(公告)日：2013-06-26

申请号：EP10185891.8

申请日：2004-05-06

申请人： Osteologix A/S

发明人： Christgau, Stephan ,  Hansen, Christian ,  Andersen, Jens ,  Nilsson, Henrik

IPC分类号： A61K33/24 ,  A61P19/08 ,  A61K31/194 ,  A61K31/198

CPC分类号： A61K33/24 ,  C07C55/08 ,  C07C55/10 ,  C07C57/145 ,  C07C59/08 ,  C07C59/19 ,  C07C59/347

公开(公告)号：EP1745791B1

公开(公告)日：2013-06-26

申请号：EP06021612.4

申请日：2004-05-06

申请人： Osteologix A/S

发明人： Hansen, Christian ,  Nilsson, Henrik ,  Andersen, Jens, E. T. ,  Christgau, Stephan

IPC分类号： A61K33/24 ,  A61P19/08 ,  A61K31/198 ,  A61K31/194

CPC分类号： A61K33/24 ,  C07C55/08 ,  C07C55/10 ,  C07C57/145 ,  C07C59/08 ,  C07C59/19 ,  C07C59/347

公开(公告)号：EP1879833A2

公开(公告)日：2008-01-23

申请号：EP06758947.3

申请日：2006-05-02

申请人： Symyx Technologies, Inc.

发明人： HAGEMEYER, Alfred ,  SCHLICHTER, Marco

IPC分类号： C01G51/00

CPC分类号： B01J23/10 ,  B01J23/002 ,  B01J23/04 ,  B01J23/08 ,  B01J23/14 ,  B01J23/20 ,  B01J23/22 ,  B01J23/28 ,  B01J23/462 ,  B01J23/72 ,  B01J23/745 ,  B01J23/75 ,  B01J23/755 ,  B01J23/83 ,  B01J23/8892 ,  B01J23/894 ,  B01J35/002 ,  B01J35/1009 ,  B01J35/1014 ,  B01J35/1019 ,  B01J35/1038 ,  B01J35/108 ,  B01J37/031 ,  B01J37/08 ,  B01J37/086 ,  B01J2219/00747 ,  B01J2219/00754 ,  B01J2523/00 ,  B82Y30/00 ,  C01B13/18 ,  C01F17/0043 ,  C01G1/02 ,  C01G31/006 ,  C01G31/02 ,  C01G39/006 ,  C01G39/02 ,  C01G51/006 ,  C01G51/04 ,  C01G53/006 ,  C01G53/04 ,  C01G55/002 ,  C01G55/004 ,  C01P2002/02 ,  C01P2002/60 ,  C01P2002/72 ,  C01P2004/61 ,  C01P2004/62 ,  C01P2004/64 ,  C01P2004/80 ,  C01P2006/12 ,  C01P2006/14 ,  C01P2006/16 ,  C01P2006/17 ,  C07C51/418 ,  C07C59/347 ,  C07C59/08 ,  C07C55/02 ,  C07C59/19 ,  C07C59/01 ,  B01J2523/36 ,  B01J2523/3712 ,  B01J2523/821 ,  B01J2523/845

摘要： The present invention is directed to methods for making metal oxide compositions, specifically, metal oxide compositions having high surface area, high metal/metal oxide content, and/or thermal stability with inexpensive and easy to handle materials. In one embodiment, the present invention is directed to methods of making metal and/or metal oxide compositions, such as supported or unsupported catalysts. The method includes combining a metal precursor with an organic acid to form a mixture and calcining the mixture for a period of time sufficient to form a metal oxide material.

公开(公告)号：EP1805126A1

公开(公告)日：2007-07-11

申请号：EP05797104.6

申请日：2005-09-30

申请人： GE Healthcare AS

发明人： ROLANDSGAARD, Marit, Amersham Health AS ,  SANDOSHAM, Jessie, Amersham Health AS ,  THOMASSEN, Terje, Amersham Health AS ,  GRACE, David, Amersham Health AS

IPC分类号： C07C51/02 ,  C07C59/19

CPC分类号： C07C51/44 ,  C07B2200/05 ,  C07C51/02 ,  C07C51/48 ,  C07C59/19

摘要： The invention relates to a method for the production of pyruvic acid.

公开(公告)号：EP0376215A2

公开(公告)日：1990-07-04

申请号：EP89123826.3

申请日：1989-12-22

申请人： AJINOMOTO CO., INC.

发明人： Tanabe, Toshiya Central Research Lab. ,  Kishimoto, Shin-ichi Central Research Lab.

IPC分类号： C07D233/64 ,  C07C277/08 ,  C07C59/185 ,  C07C229/26 ,  C07C59/84

CPC分类号： C07D233/64 ,  C07C59/185 ,  C07C59/19 ,  C07C59/84 ,  C07C229/26

摘要： α-keto acid/amino acid salts are provided, which are represented by the formula
AN·xS
wherein A represents an amino acid; N represents an α-keto acid; S represents a lower alcohol or a ketone; and x represents 0.1 to 3.
These compounds may be transformed into the non-solvated salts by treating them at an absolute humidity of 0.003 to 17.0 kg H₂O/kg dry air.

摘要翻译： 提供α-酮酸/氨基酸盐，其由式AN.xS表示，其中A表示氨基酸; N表示α-酮酸; S代表低级醇或酮; x表示0.1至3.这些化合物可以通过在0.003至17.0kg H 2 O / kg干燥空气的绝对湿度下处理而转化成非溶剂化的盐。

公开(公告)号：EP0001070B1

公开(公告)日：1981-07-15

申请号：EP78100723.2

申请日：1978-08-22

申请人： MITSUI TOATSU CHEMICALS, Inc.

发明人： Kiyoura, Tadamitsu

IPC分类号： C07C59/19 ,  C07C51/23 ,  B01J23/40

CPC分类号： C07C51/235 ,  C07C59/19

公开(公告)号：EP2916807B1

公开(公告)日：2018-12-26

申请号：EP13803122.4

申请日：2013-11-08

申请人： L'Oréal

发明人： DAUBRESSE, Nicolas

IPC分类号： A61K8/365 ,  A61K8/58 ,  A61Q5/04 ,  A61K8/36

CPC分类号： A61K8/365 ,  A45D2/001 ,  A45D7/06 ,  A61K8/36 ,  A61K8/585 ,  A61K2800/805 ,  A61Q5/04 ,  C07C59/153 ,  C07C59/19

公开(公告)号：EP1745791A3

公开(公告)日：2011-03-30

申请号：EP06021612.4

申请日：2004-05-06

申请人： Osteologix A/S

发明人： Hansen, Christian ,  Nilsson, Henrik ,  Andersen, Jens, E. T. ,  Christgau, Stephan

IPC分类号： A61K33/24 ,  A61P19/08

CPC分类号： A61K33/24 ,  C07C55/08 ,  C07C55/10 ,  C07C57/145 ,  C07C59/08 ,  C07C59/19 ,  C07C59/347

摘要： Compounds and pharmaceutical compositions for use in the treatment and/or prophylaxis of cartilage and/or bone conditions and for methods of treating such conditions. The compounds are salts of strontium that have a water-solubility of from about 1 g/l to about 100 g/l at room temperature, especially amino acid salts of strontium or dicarboxylic acid salts of strontium. Examples of novel water-soluble strontium salts are e.g. strontium glutamate and strontium alpha-ketoglutarate.
The present invention also relates to an improved method for preparing the strontium salt of glutamic acid.

公开(公告)号：EP1370509B1

公开(公告)日：2010-05-26

申请号：EP02726140.3

申请日：2002-03-05

申请人： BASF SE

发明人： GROSCH, Georg, Heinrich ,  BOCHNITSCHEK, Werner ,  NEUMANN, Peter ,  KINGMA, Arend, Jouke

IPC分类号： C07C51/06 ,  C07C51/09 ,  C07C51/41

CPC分类号： C07C51/06 ,  C07C51/09 ,  C07C59/10 ,  C07C59/19

摘要： The invention relates to the production of glyceric acid compounds of general formula (I): R1R2C(OH)-CR3(OH)-COOX, wherein R1, R2 independently represent hydrogen, C¿1-12?-alkyl, C6-12-aryl, C7-13-alkaryl or C7-13-aralkyl and X represents hydrogen, alkali, alkaline earth/2 or NH4, by saponification of glyceric acid compounds of formula (II), wherein Y represents NH2 or OR?4 with R4 C¿1-12-alkyl or C7-13-aralkyl with ring-opening addition of water to the epoxy ring. Preferably, Y represents NH2 and the glyceric acid used, corresponding to general formula (II) is produced by reacting acrylnitrile of general formula (III): R?1R2C=CR3¿CN with hydrogen peroxide.