Verfahren zur Herstellung einer wässrigen Überzugsmitteldispersion und ihre Verwendung zum Überziehen von Arzneimitteln
    1.
    发明公开
    Verfahren zur Herstellung einer wässrigen Überzugsmitteldispersion und ihre Verwendung zum Überziehen von Arzneimitteln 失效
    一种制备水性涂料剂分散体,以及它们用于药物的涂层使用过程。

    公开(公告)号:EP0181515A2

    公开(公告)日:1986-05-21

    申请号:EP85113044.3

    申请日:1985-10-15

    申请人: RÖHM GMBH

    IPC分类号: A61K9/32

    摘要: Pulverförmige, in Wasser quellbare, aber nicht lösliche Mischpolymerisate aus einer monoäthylenisch ungesättigten. radikalisch polymerisierbaren quartären Ammoniumverbindung und wenigstens einem nichtionischen wasserunlösliche Homopolymerisate bildenden, monoäthylenisch ungesättigten, radikalisch polymerisierbaren Comonomeren werden in einer wäßrigen Phase unter Rühren bei erhöhter Temperatur zu einer wäßrigen filmbildenden Überzugsmitteldispersion für Arzneimittel dispergiert, aus der sich pharmazeutische Überzüge oder Filme mit einer vom pH-Wert des umgebenden Mediums unabhängigen Diffusionsdurchlässigkeit herstellen lassen. Die Dispersionen sind nicht brennbar und erzeugen beim Verarbeiten keine explosiven oder die Abluft verunreinigenden Dämpfe.

    摘要翻译: 粉状的,不饱和单烯的水溶胀性,但不溶于共聚物。 自由基聚合的季铵化合物和至少一种非离子型的水不溶性均聚物形成,单烯键不饱和的,可自由基聚合的共聚单体被分散在水相中在高温下搅拌,以形成用于药物的水性成膜包衣剂分散体,其具有的pH值的药物涂层或膜 可以产生独立于周围介质的扩散渗透率。 该分散体是不易燃的和在处理爆炸物或不排气污染蒸气产生。

    Self-emulsifiable resin powder
    3.
    发明授权
    Self-emulsifiable resin powder 失效
    可自动生产的树脂粉

    公开(公告)号:EP0226527B1

    公开(公告)日:1991-01-30

    申请号:EP86630175.7

    申请日:1986-11-24

    发明人: Salazar, Mariano

    摘要: A self-emulsifiable resin powder can be dispersed in water without utilizing additional surfactants or expending large amounts of mechanical energy. Such self-emulsifiable resin powders offer numerous distinct advantages over conventional latices. One of the most important benefits that is realized by utilizing self-emulsifiable resin powders is that they can be shipped dry which is the equivalent to shipping a latex with a 100 percent solids content. In other words, such self-emulsifiable resin powders eliminate the necessity for shipping water in latices. The self-emulsifiable resin powders disclosed herein also have the advantage of having low carboxyl contents and of being dispersible into aqueous systems which contain virtually no surfactants. These selfemulsifiable resins contain a relatively small proportion of repeat units which are derived from both acrylic acid and methacrylic acid. The self-emulsifiable resin powder compositions disclosed herein also contain a small amount of a metal salt of an alkyl sulfonate or a metal salt of an alkyl sulfate.

    Self-emulsifiable resin powder
    4.
    发明公开
    Self-emulsifiable resin powder 失效
    Selbstemulgierbares Harzpulver。

    公开(公告)号:EP0226527A2

    公开(公告)日:1987-06-24

    申请号:EP86630175.7

    申请日:1986-11-24

    发明人: Salazar, Mariano

    摘要: A self-emulsifiable resin powder can be dispersed in water without utilizing additional surfactants or expending large amounts of mechanical energy. Such self-emulsifiable resin powders offer numerous distinct advantages over conventional latices. One of the most important benefits that is realized by utilizing self-emulsifiable resin powders is that they can be shipped dry which is the equivalent to shipping a latex with a 100 percent solids content. In other words, such self-emulsifiable resin powders eliminate the necessity for shipping water in latices. The self-emulsifiable resin powders disclosed herein also have the advantage of having low carboxyl contents and of being dispersible into aqueous systems which contain virtually no surfactants. These self-emulsifiable resins contain a relatively small proportion of repeat units which are derived from both acrylic acid and methacrylic acid. The self-emulsifiable resin powder compositions disclosed herein also contain a small amount of a metal salt of an alkyl sulfonate or a metal salt of an alkyl sulfate.

    摘要翻译: 自乳化树脂粉末可以分散在水中而不需要额外的表面活性剂或者大量的机械能量。 这种自乳化树脂粉末与常规胶乳相比具有许多明显的优点。 通过使用自乳化树脂粉末实现的最重要的好处之一是它们可以运输干燥,这相当于运输具有100%固体含量的胶乳。 换句话说,这种自乳化树脂粉末消除了在胶乳中运输水的必要性。 本文公开的自乳化树脂粉末还具有低羧基含量并且可分散到几乎不含表面活性剂的水性体系中的优点。 这些自乳化树脂含有相对较少比例的来自丙烯酸和甲基丙烯酸的重复单元。 本文公开的自乳化树脂粉末组合物还含有少量的烷基磺酸盐金属盐或烷基硫酸盐的金属盐。

    SELF-EMULSIFIABLE RESIN POWDER
    5.
    发明公开
    SELF-EMULSIFIABLE RESIN POWDER 失效
    可自动生产的树脂粉

    公开(公告)号:EP0226527A3

    公开(公告)日:1988-08-24

    申请号:EP86630175

    申请日:1986-11-24

    发明人: SALAZAR, MARIANO

    摘要: A self-emulsifiable resin powder can be dispersed in water without utilizing additional surfactants or expending large amounts of mechanical energy. Such self-emulsifiable resin powders offer numerous distinct advantages over conventional latices. One of the most important benefits that is realized by utilizing self-emulsifiable resin powders is that they can be shipped dry which is the equivalent to shipping a latex with a 100 percent solids content. In other words, such self-emulsifiable resin powders eliminate the necessity for shipping water in latices. The self-emulsifiable resin powders disclosed herein also have the advantage of having low carboxyl contents and of being dispersible into aqueous systems which contain virtually no surfactants. These selfemulsifiable resins contain a relatively small proportion of repeat units which are derived from both acrylic acid and methacrylic acid. The self-emulsifiable resin powder compositions disclosed herein also contain a small amount of a metal salt of an alkyl sulfonate or a metal salt of an alkyl sulfate.