-
公开(公告)号：EP3381529A1
公开(公告)日：2018-10-03
申请号：EP17305363.8
申请日：2017-03-29
摘要： L'invention concerne une installation de traitement de liquide biologique par chromatographie, s'étendant selon une direction longitudinale et comportant une vanne d'alimentation (20b), une pompe d'alimentation (30) en aval de la vanne, des organes d'instrumentation en aval de la pompe dont au moins une vanne de distribution (81a-c, 82a-c, 83a-c) et au moins un dispositif de mesure (78a-c, 85a-c, 86a-c) d'un paramètre physico-chimique du liquide, au moins une colonne de chromatographie (99a-c) en aval des organes d'instrumentation et des conduites connectant la vanne, la pompe, les organes d'instrumentation et la colonne, des organes d'instrumentation étant associés à la colonne de chromatographie et montés chacun sur au moins une plateforme dédiée de contrôle et de commande (80a-c), qui s'étend selon une direction verticale par rapport à la direction globalement longitudinale d'extension de ladite installation, et qui sont disposés sensiblement les uns au-dessus des autres sur ladite plateforme dédiée de contrôle et de commande.
-
公开(公告)号：EP1985693B1
公开(公告)日：2018-03-21
申请号：EP08290298.2
申请日：2008-03-28
IPC分类号： C12M1/12
摘要： The assembly comprises a filtration unit (1) and a gel growth medium cassette (80), the unit (1) and the cassette (80) being adapted to cooperate in order to occupy a nested position in which a membrane (3) covers the said gel growth medium (88), the said unit (1) and the said cassette (80) each being equipped with an intermediate stop (26, 100), it being possible for at least one of the two stops (100) to move clear so as to allow the said unit (1) to move from an intermediate position, in which the said membrane is spaced away from the said gel growth medium, into the said nested position. The method comprises the steps of selecting such an assembly, of engaging the said unit (1) on the said cassette (80) until the intermediate stop (26) of the said unit (1) comes into contact with the intermediate stop (100) of the said cassette (80), and the step of moving clear the said stop (100) able to move clear so as to allow the said unit (1) to move from the said intermediate position into the said nested position.
-
公开(公告)号：EP3279310A1
公开(公告)日：2018-02-07
申请号：EP16772117.4
申请日：2016-03-08
发明人： SUGIURA Shinji , SATOH Taku , KANAMORI Toshiyuki , SHIN Kazumi
CPC分类号： B01J19/0046 , B01F13/0059 , B01L3/502 , B01L3/502738 , B01L2200/0621 , B01L2300/0829 , B01L2300/0874 , B01L2300/088 , B01L2400/0487 , B01L2400/0688 , C12M1/005 , C12M1/04 , C12M1/12 , C12M1/36 , C12M23/04 , C12M23/16 , C12M29/10 , C12M29/14
摘要： A cell culture apparatus, includes a connected culture container including n number of units disposed in parallel along a second direction that is a different direction from a first direction where each of the n number of the units is constituted of m number of culture chambers and one or more communication-channels, the m number of the culture chambers each having a cell-holding portion that holds seeded cells, the m number of the culture chambers storing liquid culture media, the m number of the culture chambers being disposed in parallel along the first direction, the communication-channels communicating the m number of the culture chambers with each other; and a plurality of pneumatic pipes communicating same-row-disposed culture chambers that are disposed on a same row along the second direction with each other in the connected culture container, the pneumatic pipes being configured to pressurize the same-row-disposed culture chambers at the same time or open the same-row-disposed culture chambers to atmospheric pressure at the same time, the pneumatic pipes being configured to send the liquid culture media to the m number of the culture chambers through the communication-channels using pressure differences in the m number of the culture chambers, in which m is an integer of two or more, and n is an integer of two or more.
摘要翻译： 本发明提供一种细胞培养装置，该细胞培养装置具备连结培养容器，该培养容器具有n个单元沿与第一方向不同的第二方向平行配置的n个单元，所述n个单元分别由m个培养腔室构成， 或更多个通信通道，所述m个培养室各自具有容纳种子细胞的细胞容纳部分，所述m个培养室容纳液体培养基，所述m个培养室平行于 第一方向，所述通信通道将所述m个培养室相互连通; 以及多个气管，其将在连接的培养容器内沿着第二方向配置在同一列的相同排配置的培养室连通， 同时或同时打开同一排设置的培养室至大气压力，所述气动管道被配置为通过所述通信通道将所述液体培养基发送至所述m个培养室， m个培养室，其中m是2或更大的整数，并且n是2或更大的整数。
-
公开(公告)号：EP2415856B1
公开(公告)日：2013-08-28
申请号：EP11290339.8
申请日：2011-07-27
-
公开(公告)号：EP4414444A1
公开(公告)日：2024-08-14
申请号：EP22878746.1
申请日：2022-09-15
发明人： JANG, Seon Ho , HAN, Kyoung Ku , SEO, In Yong , LEE, Seoung Hoon , KOO, Song Hee , NOH, Hyeong Tak , KIM, Ji Young , LEE, Su Yeon
摘要： A bioreactor for suspended cells is provided. A bioreactor for suspended cells, according to one embodiment of the present invention, comprises: a housing which is formed in the shape of a container having a culture space with a predetermined volume, and which comprises pots for seeding; a support assembly comprising a plurality of supports arranged at intervals in multiple stages in one direction of the housing; at least one gas inlet penetrating the housing by a predetermined area; and a porous member for covering the gas inlet, wherein the culture space comprises a medium storage space filled with a predetermined amount of a medium so that all the plurality of supports are submerged therein, and the medium storage space can comprise a plurality of cell growth spaces divided through the plurality of supports arranged at intervals in multiple stages.
-
6.发明公开
公开(公告)号：EP4368294A1
公开(公告)日：2024-05-15
申请号：EP22836762.9
申请日：2022-06-28
发明人： GUO, Xiaoliang , SHANG, Yuanfang , YAO, Jialin , ZHANG, Jinxin , LIU, Fujing
IPC分类号： B04B1/00 , B04B7/12 , B04B15/00 , B04B11/02 , C12M1/00 , C12M3/00 , C12M1/12 , C12M1/10 , C12M1/04 , C12M1/02 , C12N5/00
CPC分类号： B04B1/00 , B04B7/12 , B04B11/02 , B04B15/00 , C12M1/00 , C12M1/02 , C12M1/04 , C12M1/10 , C12M1/12 , C12M3/00 , C12N5/00
摘要： The present application disclosed a cell centrifugation apparatus and a cell centrifugation, washing and culture method. The cell centrifugation apparatus comprises a centrifuge chamber (1) and a liquid pushing plate (2); the centrifuge chamber (1) has a rotation axis, and the centrifuge chamber (1) is used to connected with a rotation drive mechanism (4) and rotate around its rotation axis under drive of the rotation drive mechanism (4), so as to centrifuge a blood sample contained in the centrifuge chamber (1); and one or more liquid pushing plates (2) are arranged in the centrifuge chamber (1), when the centrifuge chamber (1) rotates, the liquid pushing plate (2) is used to push the blood sample to rotate synchronously along the same rotation direction as the centrifuge chamber (1).
-
公开(公告)号：EP3095850A1
公开(公告)日：2016-11-23
申请号：EP15877420.8
申请日：2015-01-14
发明人： LIU, Tao
IPC分类号： C12M1/12
CPC分类号： C12M47/04 , A61M1/3633 , B01D63/062 , B01D67/0032 , C12M1/12 , C12M25/06 , C12M29/00 , C12M41/40
摘要： The present disclosure provides a device for separating cells in fluid, comprising a first driving pump, a separation column, a detection column, a second driving pump, and several three-way valves and secondary driving pumps; one end of the separation column is connected with the first driving pump through a first three-way valve; the other end is connected with the second driving pump through a second three-way valve; the separation column includes at least five sub filtration columns in parallel; the sub filtration column comprises a fixing bracket and a track-etched membrane of polycarbonate or polyester material attached to the bottom of and the side surfaces all around the fixing bracket, wherein the pore diameter of the track-etched membrane is 5-25 µm. The device of the present disclosure not only provides a new method for accurately determining whether there are circulating tumor cells in the blood of the living animal and provides a new method for sorting and counting the circulating tumor cells in the blood of the living animal, but also provides a pioneering new method and new device for therapy of the tumor transfer and removal of the tumor cells inside the body, and has extremely high economic and social values.
摘要翻译： 本发明提供了一种分离流体中细胞的装置，包括第一驱动泵，分离柱，检测柱，第二驱动泵以及若干个三通阀和二级驱动泵; 分离柱的一端通过第一三通阀与第一驱动泵连接， 另一端通过第二三通阀与第二驱动泵连接; 分离塔包括至少五个平行的子过滤塔; 所述分过滤柱包括固定支架和聚碳酸酯或聚酯材料的履带蚀刻膜，所述聚碳酸酯或聚酯材料膜附着在所述固定支架的整个底部和侧表面上，其中所述履带蚀刻膜的孔径为5-25μm。 本发明的装置不仅提供了一种准确判断活体动物血液中是否存在循环肿瘤细胞的新方法，为活体动物血液中循环肿瘤细胞的分选和计数提供了新的方法， 也为肿瘤转移和体内肿瘤细胞的清除提供了开创性的新方法和新器件，具有极高的经济和社会价值。
-
公开(公告)号：EP2130903B1
公开(公告)日：2015-04-15
申请号：EP09290402.8
申请日：2009-05-29
发明人： Beulay, Jean-Luc , Buisson, Virginie , Cirou, Sébastien , Delbos, Cécile , Hlavacek, Marc , Mels, Frans , Reinbigler, René , Weissenbach, Jean-Louis
IPC分类号： C12M1/12
CPC分类号： B01D36/00 , C12M1/12 , C12M47/12 , Y10T436/25375 , Y10T436/2575
-
公开(公告)号：EP2678417A1
公开(公告)日：2014-01-01
申请号：EP12750008.0
申请日：2012-02-22
发明人： FRICKING, Patric
摘要： The present invention relates to a bioreactor and a method for operating a bioreactor which comprises a chamber(100) capable of receiving a liquid media, and a filter assembly (200) comprising a perfusion filter(210; 212; 214). The filter assembly (200) is disposed in the chamber(100) and the filter assembly (200) is free to move within the chamber(100). The filter assembly(200) comprises means for coupling a harvesting flow through said filter (210; 212; 214) and means for coupling a feed flow through said filter in an opposite direction compared to the harvesting flow. Through this arrangement, the clogging prevention of the perfusion filter can be improved.
-
公开(公告)号：EP4438712A1
公开(公告)日：2024-10-02
申请号：EP22899053.7
申请日：2022-11-24
发明人： KANG, Seok-Gu , SUNG, Hak-Joon , BAEK, Se Woom
摘要： The present invention relates to a tumor tissue model in which tumor tissue isolated from a patient can be cultured. The tumor tissue model uses tumor tissue isolated from a patient, and thus the tumor tissue can be cultured while maintaining the extracellular matrix of tumor cells. Since the tumor tissue is cultured in an environment similar to the actual environment inside the body, the tumor tissue model can be used for patient-tailored drug screening, drug response evaluation, radiation reactivity evaluation, tumor-related research, clinical evaluation, animal replacement tests, disease modeling, etc.
-
-
-
-
-
-
-
-
-
搜索结果
36 条记录 (耗时 0.017 秒)
