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    Micromechanic passive flow regulator
    6.
    发明公开
    Micromechanic passive flow regulator 审中-公开
    Mikromechanischer passiver Durchflussregler

    公开(公告)号：EP2359886A1

    公开(公告)日：2011-08-24

    申请号：EP10153449.3

    申请日：2010-02-12

    申请人： Debiotech S.A.

    发明人： Chappel, Eric

    IPC分类号： A61M5/168 ,  A61M27/00 ,  F15C3/04 ,  F15C5/00 ,  F16K11/00 ,  G05D7/01 ,  F16K99/00

    CPC分类号： A61M5/16881 ,  A61M5/14276 ,  A61M5/145 ,  A61M5/16813 ,  A61M27/006 ,  A61M2039/2413 ,  A61M2205/0244 ,  F16K99/0001 ,  F16K99/0015 ,  F16K99/0057 ,  F16K2099/008 ,  F16K2099/0088 ,  G05D7/0635 ,  G05D7/0694 ,  Y10T137/7791 ,  Y10T137/86734

    摘要： A new design of flow regulator is proposed. The device is preferably made of a stack of 3 plates, respectively a top plate including a flexible membrane, a middle plate with pillars and vias and a bottom plate with fluidic ports, micro channels and vias.
    The principle is based on the deformation of the membrane due to the pressure of the liquid. The membrane goes in contact with the pillars of the middle plate, obstructing gradually the vias of the pillars. The device is preferably designed to keep the flow constant in a predefined range of pressure.
    The device is dedicated to ultra low flow rate up to 1 ml per day or below, typically for drug infusion.
    Plastic flow regulators comprise preferably several independent valves coupled in parallel. The membrane plate is therefore made of several flexible membranes obstructing gradually the flow by increasing the pressure. Stress limiters are used to avoid plastic deformation of the membrane.
    For implanted pump, the use of a flow regulator instead of a flow restrictor has several advantages, including the possibility to reduce significantly the reservoir pressure and to generate directly the pressure during the pump filling by using an elastic drug reservoir.

    摘要翻译： 提出了一种流量调节器的新设计。 该装置优选由3个板的堆叠构成，分别是包括柔性膜的顶板，具有支柱和通孔的中间板以及具有流体端口的底板，微通道和通孔。 原理是由于液体的压力导致膜的变形。 膜与中间板的支柱接触，逐渐阻碍柱的通孔。 该装置优选地设计成将流量保持在预定的压力范围内。 该设备专用于每天或以下超过1毫升的超低流速，通常用于药物输注。 塑料流量调节器优选地并联连接多个独立的阀。 因此，膜片由几个柔性膜制成，通过增加压力来逐渐阻塞流动。 应力限制器用于避免膜的塑性变形。 对于植入泵，使用流量调节器而不是限流器具有若干优点，包括显着降低储层压力并通过使用弹性药物储存器直接产生泵填充期间的压力的可能性。

    FLOW CONTROL SYSTEMS
    9.
    发明公开
    FLOW CONTROL SYSTEMS 有权
    FLUSSTEUERSYSTEME

    公开(公告)号：EP1407330A4

    公开(公告)日：2005-08-17

    申请号：EP02739909

    申请日：2002-06-13

    申请人： EKSIGENT TECHNOLOGIES LLC

    发明人： NEYER DAVID W ,  PAUL PHILLIP H ,  ARNOLD DON WESLEY ,  BAILEY CHRISTOPHER G

    IPC分类号： B01D61/56 ,  G01N30/32 ,  G05D7/06 ,  G05D11/13 ,  G05B1/00

    CPC分类号： G01N30/32 ,  B01D61/56 ,  G01N2030/324 ,  G01N2030/326 ,  G05D7/0694 ,  G05D11/132 ,  Y10T137/85978 ,  Y10T137/85986 ,  Y10T137/86027 ,  G01N30/34 ,  G01N2030/285

    摘要： A flow controller which uses a combination of hydrostatic pressure and electroosmotic flow to control the flow of a fluid. A driving fluid (1204) whose flow rate is dependent on both hydrostatic pressures and electroosmotic flow can be used (a) directly as a working fluid in an operable device, for example a chromatograph, or (b) to displace a working fluid (1203) from a storage container (625) into an operable device (1301), or both (a) and (b). The driving fluid (1204) can be composed of one or more fluids. Part or all the driving fluid (1204) is passed through an electroosmotic device (100) so as to increase or decrease the flow rate induced by hydrostatic pressure.

    摘要翻译： 一种使用流体静压和电渗流的组合来控制流体流动的流量控制器。 其流速取决于流体静压和电渗流两者的驱动流体（1204）可以（a）直接用作可操作装置（例如色谱仪）中的工作流体，或（b）置换工作流体（1203） ）从存储容器（625）转移到可操作装置（1301）中，或（a）和（b）两者。 驱动流体（1204）可以由一种或多种流体构成。 部分或全部驱动流体（1204）通过电渗透装置（100），以增加或减少流体静压所引起的流速。