摘要:
The technology described herein is directed to compositions comprising at least a first porous biomaterial layer and a second impermeable biomaterial layer and methods relating thereto. In some embodiments, the compositions and methods described herein relate to wound healing, e.g. repair of wounds and/or tissue defects.
摘要:
A scaffold material for wound care and/or other tissue healing applications and methods for making the same is described. The scaffold material is constituted of a decellularized extracellular matrix from fish skin. The scaffold material may also include lipids from the lipid layer of the fish skin. Methods for making and using the scaffold material are also described.
摘要:
The invention concerns a hydrophobic grafted collagen, a method for preparing same and use thereof, in particular in therapy. In the present invention, hydrophobic substances or molecules are grafted by covalent bonds on reactive amino acid residues of collagen molecules. The chemical linkages serve to modify the physico-chemical and biological properties of collagen and/or its derivatives. In particular, the introduction of hydrophobic residues enable the hydrophilic character of collagen to be modulated and its chemotactic properties involved in cell adhesion and growth to be modified.
摘要:
The invention relates to a surgical thread comprising - a thread body comprising or consisting of a self-sticking material being capable of sticking to a biological tissue upon contact with the biological tissue and/or an activator or - a thread body and a coating, wherein the coating at least partially surrounds the thread body, wherein the coating comprises or consists of a self-sticking material being capable of sticking to a biological tissue upon contact with the biological tissue and/or an activator. The invention further relates to a surgical device, a surgical kit and a method for preparing the surgical thread.
摘要:
A method for improving bioactivity and/or biodegradation time of a collagen surgical implant and collagen surgical implants having such improved properties. A gas-cluster ion-beam (GCIB) is formed in a reduced-pressure chamber, a collagen surgical implant is introduced into the reduced-pressure chamber, and at least a first portion of the surface of said collagen surgical implant is irradiated with a GCIB-derived beam.
摘要:
The technology described herein is directed to compositions comprising at least a first porous biomaterial layer and a second impermeable biomaterial layer and methods relating thereto. In some embodiments, the compositions and methods described herein relate to wound healing, e.g. repair of wounds and/or tissue defects.
摘要:
Embodiments of the disclosed technology provide systems, devices, and methods of creating an electrosurgical tissue seal that is augmented with a seal-enhancing composition. One embodiment of a device includes a set of opposing electrosurgical jaws configured to be able to close on a targeted tissue-sealing site; the jaws have a reservoir configured to hold a tissue seal- enhancing composition. The reservoir is in communication with a surface of the tissue-sealing site when the jaws are closed on the site, and the electrosurgical device is configured to deliver the tissue seal-enhancing composition to the site during an electrosurgical procedure. The device is further configured to deliver sufficient radiofrequency energy to the site such that the targeted tissue and the tissue seal-enhancing composition at the tissue-sealing site are processed to form a high integrity sealed tissue site.