公开(公告)号：EP3573672B1

公开(公告)日：2024-08-28

申请号：EP18745077.0

申请日：2018-01-26

IPC分类号： A61L17/08 ,  A61L15/32 ,  A61L15/64 ,  C07K14/78 ,  C08L5/02 ,  C08L89/06 ,  D01F8/02 ,  A61L27/24 ,  A61L27/38 ,  A61L27/48 ,  A61L27/50

CPC分类号： C07K14/78 ,  C08L5/02 ,  C08L89/06 ,  A61L27/26 ,  A61L27/3804 ,  A61L27/52 ,  A61L27/54 ,  A61L27/56 ,  A61L15/225 ,  A61L15/44 ,  D06M15/03 ,  D06M15/285 ,  D01D5/00 ,  D01F4/00 ,  D01F9/00 ,  D06M2101/1420130101 ,  A61L27/48 ,  A61L27/24 ,  A61L27/50 ,  A61L27/3826 ,  A61L2430/3020130101

公开(公告)号：EP3233904A4

公开(公告)日：2018-07-25

申请号：EP15870925

申请日：2015-12-15

申请人： UNIV NORTHEASTERN

发明人： PATEN JEFFREY A ,  RUBERTI JEFFREY W

IPC分类号： C07K14/78 ,  A61M5/142 ,  A61M5/172

CPC分类号： A61L27/24 ,  A61H1/008 ,  A61H1/02 ,  A61K9/0019 ,  A61K38/39 ,  A61K38/47 ,  A61K38/4873 ,  A61K38/4886 ,  A61K47/183 ,  A61L27/50 ,  A61L27/54 ,  A61L2300/41 ,  A61L2300/426 ,  A61L2400/06 ,  A61L2430/10 ,  A61M5/14 ,  A61M5/142 ,  A61M5/14248 ,  A61M2202/095 ,  A61M2205/50 ,  A61N1/0456 ,  C12Y302/01035 ,  C12Y304/22001 ,  C12Y304/24 ,  C12Y304/24007 ,  D01D5/00 ,  D01F4/00 ,  D10B2509/00 ,  A61K2300/00

摘要： Methods and devices for tissue remodeling and repair of collagenous tissues, including tendons, ligaments, and bone, as well as scalable connective tissue manufacturing, are provided. Collagen fibers are assembled by extensional strain-induced flow crystallization of collagen monomers. Extensional strain also drives the fusion of already formed short collagen fibrils to produce long-range, continuous fibers. Wearable devices for controlled tissue remodeling and wound healing deliver a tissue remodeling solution to a tissue repair site. The remodeling solution, together with appropriate application of strain to the tissue remodeling site, accelerate healing, prevent injury, and reduce scar formation.

公开(公告)号：EP3312327A4

公开(公告)日：2018-05-23

申请号：EP16811022

申请日：2016-06-16

申请人： MEDPRIN REGENERATIVE MEDICAL TECH CO LTD

发明人： LI GUANGYAO ,  DENG KUNXUE ,  YANG YAYA ,  YUAN YUYU

IPC分类号： D04H1/728 ,  D01D5/00 ,  D04H1/42

CPC分类号： D01D5/00 ,  D04H1/42 ,  D04H1/728

摘要： The present application discloses a reinforced electrospun fibrous membrane and a preparation method thereof. The reinforced electrospun fibrous membrane comprises: an electrospun fibrous membrane body and a plurality of parallel reinforcing thread sets fixed to the electrospun fibrous membrane body via through holes thereon, wherein each of the reinforcing thread sets comprises a starting end and a terminal end, both being connected to an edge of the electrospun fibrous membrane body; each of the reinforcing thread sets comprises at least one reinforcing fibrous thread comprising a main thread and an auxiliary thread respectively arranged at a front side and a bottom side of the electrospun fibrous membrane body and configured to interlace each other at the through hole. By providing reinforcing thread sets on the electrospun fibrous membrane body to impart the electrospun fibrous membrane with a greater mechanical property, the mechanical strength required for the movement of the tissue is ensured, and the electrospun fibrous membrane is easy to be folded or rolled into other shapes. The electrospun fibrous membrane body may be made of degradable materials, which are gradually degraded and absorbed in the process of inducing new tissue formation, thereby providing space for the formation of new tissues.

公开(公告)号：EP3233904A2

公开(公告)日：2017-10-25

申请号：EP15870925.3

申请日：2015-12-15

申请人： Northeastern University

发明人： PATEN, Jeffrey, A. ,  RUBERTI, Jeffrey, W.

IPC分类号： C07K14/78

CPC分类号： A61L27/24 ,  A61H1/008 ,  A61H1/02 ,  A61K9/0019 ,  A61K38/39 ,  A61K38/47 ,  A61K38/4873 ,  A61K38/4886 ,  A61K47/183 ,  A61L27/50 ,  A61L27/54 ,  A61L2300/41 ,  A61L2300/426 ,  A61L2400/06 ,  A61L2430/10 ,  A61M5/14 ,  A61M5/142 ,  A61M5/14248 ,  A61M2202/095 ,  A61M2205/50 ,  A61N1/0456 ,  C12Y302/01035 ,  C12Y304/22001 ,  C12Y304/24 ,  C12Y304/24007 ,  D01D5/00 ,  D01F4/00 ,  D10B2509/00 ,  A61K2300/00

摘要： Methods and devices for tissue remodeling and repair of collagenous tissues, including tendons, ligaments, and bone, as well as scalable connective tissue manufacturing, are provided. Collagen fibers are assembled by extensional strain-induced flow crystallization of collagen monomers. Extensional strain also drives the fusion of already formed short collagen fibrils to produce long-range, continuous fibers. Wearable devices for controlled tissue remodeling and wound healing deliver a tissue remodeling solution to a tissue repair site. The remodeling solution, together with appropriate application of strain to the tissue remodeling site, accelerate healing, prevent injury, and reduce scar formation.

摘要翻译： 提供了用于组织重塑和胶原组织修复的方法和装置，包括肌腱，韧带和骨以及可伸缩的结缔组织制造。 胶原纤维通过胶原单体的拉伸应变引发的流动结晶来组装。 拉伸应变也驱动已经形成的短胶原纤维的融合以产生长距离连续纤维。 用于受控组织重塑和伤口愈合的可穿戴设备将组织重塑溶液递送至组织修复部位。 重塑溶液，连同对组织重塑部位的适当应变，加速愈合，防止损伤并减少瘢痕形成。

公开(公告)号：EP2815005A4

公开(公告)日：2016-02-24

申请号：EP13749182

申请日：2013-02-14

申请人： UNIV CORNELL

发明人： JOO YONG LAK ,  WIESNER ULRICH ,  PARK JAY HOON

IPC分类号： D01D5/00 ,  B22F1/00 ,  B22F3/00 ,  B22F3/24 ,  B22F9/06 ,  B82Y30/00 ,  C04B35/624 ,  C04B35/632 ,  C04B35/634 ,  D01D5/247 ,  D01F1/08 ,  D01F6/28 ,  D01F6/30 ,  D01F6/36 ,  D01F6/38 ,  D01F9/08 ,  D01F9/10 ,  D02J13/00 ,  D04H1/728 ,  D04H3/016

CPC分类号： D01F9/08 ,  B22F1/0025 ,  B22F1/004 ,  B22F1/0044 ,  B22F3/002 ,  B22F9/06 ,  B22F2003/244 ,  B22F2304/05 ,  B22F2999/00 ,  B82Y30/00 ,  C04B35/62236 ,  C04B35/6224 ,  C04B35/6225 ,  C04B35/624 ,  C04B35/62844 ,  C04B35/6325 ,  C04B35/63408 ,  C04B35/63416 ,  C04B35/63424 ,  C04B35/63432 ,  C04B35/63444 ,  C04B35/63468 ,  C04B35/63488 ,  C04B2235/441 ,  C04B2235/443 ,  C04B2235/444 ,  C04B2235/449 ,  C04B2235/483 ,  C04B2235/526 ,  C04B2235/5264 ,  C04B2235/5284 ,  C04B2235/5409 ,  D01D5/00 ,  D01D5/0007 ,  D01D5/0015 ,  D01D5/247 ,  D01F1/08 ,  D01F6/28 ,  D01F6/30 ,  D01F6/36 ,  D01F6/38 ,  D01F9/10 ,  D02J13/00 ,  D04H1/728 ,  D04H3/016 ,  Y10T428/12993 ,  Y10T428/2975 ,  C22C1/08

摘要： Described herein are nanofibers and methods for making nanofibers that have a plurality of pores. The pores have of any suitable size or shape. In some embodiments the pores are “mesopores”, having a diameter between 2 and 50 nm. In some embodiments, the pores are “ordered”, meaning that they have a substantially uniform shape, a substantially uniform size and/or are distributed substantially uniformly through the nanofiber. Ordering of the pores results in a high surface area and/or high specific surface area. Ordered pores, without limitation, result in a nanofiber that is substantially flexible and/or non-brittle. The nanofibers and methods for making nanofibers may be used, without limitation, in batteries, capacitors, electrodes, solar cells, catalysts, adsorbers, filters, membranes, sensors, fabrics and/or tissue regeneration matrixes.

公开(公告)号：EP2780150A4

公开(公告)日：2015-10-28

申请号：EP12867106

申请日：2012-11-16

申请人： HARVARD COLLEGE

发明人： PARKER KEVIN KIT ,  BADROSSAMAY MOHAMMAD REZA ,  GOSS JOSUE ADRIAN

IPC分类号： B29C55/00 ,  D01D5/00 ,  D01D5/098 ,  D01D5/18

CPC分类号： B29D99/0078 ,  D01D5/00 ,  D01D5/0985 ,  D01D5/18 ,  D01F6/625 ,  Y10T428/249921

公开(公告)号：EP2483460B1

公开(公告)日：2015-09-02

申请号：EP10819652.8

申请日：2010-09-28

申请人： Trustees of Tufts College

发明人： LO, Tim Jia-Ching ,  LEISK, Gary G ,  KAPLAN, David L

IPC分类号： D01F4/02 ,  D01D1/02 ,  D01D5/00 ,  G02B6/02

CPC分类号： D01F4/02 ,  D01D1/02 ,  D01D5/00 ,  G02B6/02033

公开(公告)号：EP2748358B1

公开(公告)日：2015-03-11

申请号：EP13728264.6

申请日：2013-05-13

申请人： Mohawk Industries Inc.

发明人： CLARK, Thomas

IPC分类号： D01D1/10 ,  B29C47/42 ,  B29C47/76 ,  C08J11/04 ,  D01F6/42

CPC分类号： B29B17/02 ,  B01D29/0095 ,  B29B17/00 ,  B29B2017/0015 ,  B29B2017/0224 ,  B29C47/0014 ,  B29C47/008 ,  B29C47/366 ,  B29C47/42 ,  B29C47/50 ,  B29C47/766 ,  B29C47/92 ,  B29C2947/922 ,  B29C2947/92514 ,  B29C2947/92876 ,  B29D99/0078 ,  B29K2067/003 ,  B29K2105/0067 ,  B29K2105/26 ,  C08J11/04 ,  C08J11/06 ,  C08J2367/02 ,  D01D1/103 ,  D01D1/106 ,  D01D5/00 ,  D01D5/08 ,  D01F6/62 ,  D10B2503/04 ,  Y02P20/143 ,  Y02W30/70

摘要： A method of manufacturing bulked continuous carpet filament which, in various embodiments, comprises: (A) grinding recycled PET bottles into a group of flakes; (B) washing the flakes; (C) identifying and removing impurities, including impure flakes, from the group of flakes; (D) passing the group of flakes through an MRS extruder while maintaining the pressure within the MRS portion of the MRS extruder between 0.5 and 5 millibars; (E) passing the resulting polymer melt through at least one filter having a micron rating of less than about 50 microns; and (F) forming the recycled polymer into bulked continuous carpet filament that consists essentially of recycled PET.

公开(公告)号：EP1899157B1

公开(公告)日：2013-12-11

申请号：EP06800007.4

申请日：2006-07-06

申请人： Specialty Coating Systems, Inc.

发明人： KUMAR, Rakesh ,  SINGH, Bawa ,  LEWIS, Brian, G. ,  MARCZI, Michael, T. ,  HANEFELD, Phillip ,  KRIHA, Olaf ,  GREINER, Andreas

IPC分类号： D01D5/00 ,  D01F6/96 ,  B01J13/14

CPC分类号： D01D5/00 ,  B01J13/14 ,  D01F6/96 ,  D01F9/20

公开(公告)号：EP2547810A1

公开(公告)日：2013-01-23

申请号：EP11709018.3

申请日：2011-03-16

申请人： Amsilk GmbH

发明人： BAUSCH, Andreas ,  RAMMENSEE, Sebastian

IPC分类号： D01F1/02 ,  D01F4/00 ,  D01F6/68 ,  C07K14/425 ,  C07K14/435

CPC分类号： D01F6/68 ,  C07K7/06 ,  C07K14/43563 ,  D01D5/00 ,  D01F1/02 ,  D01F4/00

摘要： The present invention relates to a method of spinning a polypeptide polymer containing fibre. It further relates to a polymer fibre obtainable by said method and to uses thereof. The invention also relates to products comprising said polymer fibre.