CELLULAR GROWTH PROMOTING PEPTIDES DERIVED FROM RICE PROTEINS (ORYZA SATIVA) AND USES THEREOF

    公开(公告)号:EP4219521A2

    公开(公告)日:2023-08-02

    申请号:EP22208048.3

    申请日:2016-07-18

    申请人: Nuritas Limited

    IPC分类号: C07K20060101

    摘要: A natural peptide comprising a cellular growth promoting fragment of a protein selected from SEQUENCE ID NO's: 1 to 13, and a composition comprising a plurality of growth promoting peptides, is described. Also disclosed is the use of the peptides and compositions in prevention of ageing of human skin, treatment of diseases or conditions characterised by damaged epithelial cells or tissue such as colon cancer and peripheral inflammatory disorders, and wound treatment. Specific pea and rice protein derived peptides are described in SEQUENCE ID NO'S 15 to 505, and 546 to 704.

    AMNIOTIC-DERIVED PEPTIDE AND USES THEREOF
    3.
    发明公开
    AMNIOTIC-DERIVED PEPTIDE AND USES THEREOF 审中-公开
    羊膜肽及其用途

    公开(公告)号:EP1699809A4

    公开(公告)日:2009-10-21

    申请号:EP04810823

    申请日:2004-11-12

    申请人: LAJOR BIOTECH INC

    CPC分类号: C07K14/555 A61K38/00 C07K7/06

    摘要: The present invention relates to the method(s) of synthesis of and the therapeutic and cosmetic applications of biologically active peptides for improving the appearance of skin, for hastening wound healing and for treating and/or preventing the progression of various conditions, injuries and diseases, including but not limited to viral hepatitis B and C, herpes zoster ganglioneuritis, diabetic peripheral polyneuropathy, nephrotic syndrome, juvenile rheumatoid arthritis, rheumatoid arthritis, psoriatic arthritis, bronchial asthma, respiratory infection, breast cancer, epilepsy, psoriasis, atherosclerosis and other forms of vascular obstructions, myocardial infarction, HIV and SARS infection, brain cell malfunction due to ischemia and trauma, pathologic consequences of ischemia-reperfusion, rejection reaction following organ transplantation, chemical and drug intoxication including but not limited to anesthetic, alcohol and morphine, cancer, type 1 diabetes mellitus, multiple sclerosis, septic shock (Gram negative sepsis), Parkinson's disease, type 2 diabetes mellitus, Alzheimer's disease, amyotrophic lateral sclerosis, hyperthyroidism, Guillain-Barre syndrome, systematic lupus erythematosus, parasitic infections, especially leishmaniasis, and other collagen diseases, and diseases in which apoptosis occurs.

    CAPTURE AND RELEASE BASED ISOTOPE TAGGED PEPTIDES AND METHODS FOR USING THE SAME
    7.
    发明公开
    CAPTURE AND RELEASE BASED ISOTOPE TAGGED PEPTIDES AND METHODS FOR USING THE SAME 审中-公开
    ON抓放基于同位素标签化的肽和申请流程。

    公开(公告)号:EP1631553A4

    公开(公告)日:2008-09-10

    申请号:EP04816744

    申请日:2004-06-07

    申请人: HARVARD COLLEGE

    摘要: The invention provides isotope tagged peptides, chemistries for making these peptides, and methods for using these peptides. In one aspect, tags comprise a reactive site (RS) for reacting with a molecule on a protein to form a stable association with the peptide (e.g., a covalent bond) and an anchoring site (AS) group for reversibly or removably anchoring the tag to a solid phase such as a resin support. Anchoring may be direct or indirect (e.g., through a linker molecule). Preferably, the anchoring site comprises a biotin compound. Preferably, the tag comprises a mass-, altering label, such as a stable isotope, such that association of the tag with the peptide can be monitored by mass spectrometry. The reagents can be used for rapid and quantitative analysis of proteins or protein function in mixtures of proteins.