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公开(公告)号：JPH09110840A
公开(公告)日：1997-04-28
申请号：JP26996296
申请日：1996-10-11
申请人： HOFFMANN LA ROCHE
发明人： FUORUKAA BUROI , KASUPAARU BURI , JIINNMARII KATSUSARU , MARUCHIN KUROOZE , JIYORUJIYU HIRUTO , BERUNDOOMIKAERU REFURAA , MARUSERU MIYURAA , BUERUNAA NAIDOHARUTO , ANRI RAMIYU
IPC分类号： C07D239/52 , A61K31/495 , A61K31/505 , A61K31/535 , A61P9/00 , A61P9/08 , A61P9/10 , A61P9/12 , C07D239/46 , C07D239/557 , C07D239/56 , C07D239/58 , C07D239/69 , C07D401/12 , C07D401/14 , C07D403/06 , C07D403/12 , C07D405/04
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公开(公告)号：JP2545200B2
公开(公告)日：1996-10-16
申请号：JP14600394
申请日：1994-06-28
申请人： HOFFMANN LA ROCHE
发明人： FUORUKAA BUROI , KASUPAARU BURI , JIINNMARII KATSUSARU , MARUCHIN KUROOZE , JORUJU HIRUTO , BERUNDOOMIKAERU REFURAA , MARUSERU MYURAA , UERUNAA NAIDOHARUTO , ANRI RAMYU
IPC分类号： A61K31/505 , A61K20060101 , A61K31/33 , A61K31/495 , A61K31/535 , A61K31/55 , A61K31/63 , A61K31/635 , A61P1/04 , A61P9/00 , A61P9/08 , A61P9/10 , A61P9/12 , A61P11/08 , A61P13/02 , A61P15/00 , A61P25/04 , A61P27/02 , C07C311/20 , C07D20060101 , C07D233/46 , C07D239/02 , C07D239/22 , C07D239/24 , C07D239/28 , C07D239/42 , C07D239/46 , C07D239/47 , C07D239/49 , C07D239/50 , C07D239/52 , C07D239/545 , C07D239/56 , C07D239/69 , C07D401/10 , C07D401/12 , C07D401/14 , C07D403/04 , C07D403/12 , C07D403/14 , C07D405/00 , C07D405/10 , C07D405/12 , C07D405/14 , C07D407/14 , C07D409/00 , C07D409/04 , C07D409/10 , C07D409/12 , C07D409/14 , C07D413/00 , C07D413/04 , C07D413/10 , C07D413/12 , C07D413/14 , C07D417/12 , C07D417/14
摘要： Compounds of the formula in which R to R , R , R , X, Y, Z, m and n have the meaning given in the description, can be used as medicines, in particular for the treatment and prophylaxis of conditions associated with endothelin activities.
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公开(公告)号：JPH08208625A
公开(公告)日：1996-08-13
申请号：JP30093395
申请日：1995-11-20
申请人： HOFFMANN LA ROCHE
发明人： FUORUKAA BUROI , KASUPAARU BURI , JIINNMARII KATSUSARU , MARUCHIN KUROOZE , JIYORUJIYU HIRUTO , BERUNDOOMIKAERU REFURAA , MARUSERU MIYURAA , BUERUNAA NAIDOHARUTO , ANRI RAMIYU
IPC分类号： C07D239/46 , A61K31/4427 , A61K31/505 , A61K31/506 , A61K31/535 , A61P9/00 , A61P9/10 , A61P9/12 , A61P43/00 , C07D213/00 , C07D239/00 , C07D239/47 , C07D261/02 , C07D277/02 , C07D317/48 , C07D333/02 , C07D401/12 , C07D401/14 , C07D405/12 , C07D405/14 , C07D409/12 , C07D409/14 , C07D413/12 , C07D413/14 , C07D417/12
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公开(公告)号：JPH0717972A
公开(公告)日：1995-01-20
申请号：JP14600394
申请日：1994-06-28
申请人： HOFFMANN LA ROCHE
发明人： FUORUKAA BUROI , KASUPAARU BURI , JIINNMARII KATSUSARU , MARUCHIN KUROOZE , JIYORUJIYU HIRUTO , BERUNDOOMIKAERU REFURAA , MARUSERU MIYURAA , BUERUNAA NAIDOHARUTO , ANRI RAMIYU
IPC分类号： A61K31/505 , A61K20060101 , A61K31/33 , A61K31/495 , A61K31/535 , A61K31/55 , A61K31/63 , A61K31/635 , A61P1/04 , A61P9/00 , A61P9/08 , A61P9/10 , A61P9/12 , A61P11/08 , A61P13/02 , A61P15/00 , A61P25/04 , A61P27/02 , C07C311/20 , C07D20060101 , C07D233/46 , C07D239/02 , C07D239/22 , C07D239/24 , C07D239/28 , C07D239/42 , C07D239/46 , C07D239/47 , C07D239/49 , C07D239/50 , C07D239/52 , C07D239/545 , C07D239/56 , C07D239/69 , C07D401/10 , C07D401/12 , C07D401/14 , C07D403/04 , C07D403/12 , C07D403/14 , C07D405/00 , C07D405/10 , C07D405/12 , C07D405/14 , C07D407/14 , C07D409/00 , C07D409/04 , C07D409/10 , C07D409/12 , C07D409/14 , C07D413/00 , C07D413/04 , C07D413/10 , C07D413/12 , C07D413/14 , C07D417/12 , C07D417/14
摘要： Compounds of the formula in which R to R , R , R , X, Y, Z, m and n have the meaning given in the description, can be used as medicines, in particular for the treatment and prophylaxis of conditions associated with endothelin activities.
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公开(公告)号：JPH06211810A
公开(公告)日：1994-08-02
申请号：JP30921993
申请日：1993-12-09
申请人： HOFFMANN LA ROCHE
发明人： FUORUKAA BUROI , KASUPAARU BURI , JIINNMARII KATSUSARU , MARUCHIN KUROOZE , JIYORUJIYU HIRUTO , BERUNDOOMIKAERU REFURAA , MARUSERU MIYURAA , BUERUNAA NAIDOHARUTO , ANRI RAMIYU
IPC分类号： A61K31/505 , A61K31/506 , A61K31/535 , A61K31/5377 , A61P9/00 , A61P9/10 , A61P9/12 , A61P43/00 , C07D239/46 , C07D239/47 , C07D239/48 , C07D239/52 , C07D239/56 , C07D239/69 , C07D401/12 , C07D403/12 , C07D405/12 , C07D409/12 , C07D413/04 , C07D413/14
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