摘要:
PROBLEM TO BE SOLVED: To provide a temperature-responsive monolithic porous body in which a polymer with hydration force changing within the temperature range between 0-80°C is highly densely immobilized to the surface of a porous body, to provide a method for manufacturing the same, and to provide a temperature-responsive chromatography method using a carrier thereof.SOLUTION: An atom transfer radical polymerization initiator is immobilized to the surface of a monolithic porous body, and a polymer with hydration force changing within the temperature range between 0-80°C is made to produce a growth reaction by an atomic transfer radical method under a catalyst from the initiator.
摘要:
The present invention relates to a solid and method useful in separating chemical components in a complex mixture when at least one of the chemical components of the mixture is capable of being selectively adsorbed. The solid of the present invention comprises an inorganic substance and moieties (R 10 ) located on at least one surface of the inorganic substance, wherein said inorganic substance is an inorganic oxide and the surface moiety is selected from the group consisting of -CH 2 OH, -CH(OH) 2 , -CH(OH)CH 3 , -CH 2 CH 2 OH, -C(OH) 2 CH 3 , -CH 2 CH(OH) 2 and -CH(OH)CH 2 (OH). Binding moiety, optionally attached to the inorganic substance via a linker, can also be located on the surface of the solid.
摘要:
The present invention relates to mixed-modal anion-exchange materials composed of a support on which a ligand is immobilized. The ligand combines at least one basic domain based on cyclic aza derivatives with two or more rings as anion-exchange domain and at least one non-ionic binding domain. The basic domain is ionized under the conditions of use and may contain secondary, tertiary, or quaternary nitrogen forming a weakly (WAX) or strongly (SAX) basic anionic exchange domains. The non-ionic binding domain allows adjustment of the overall hydrophobicity / hydrophilicity of the material and represents a second binding site for the solute to be separated. Binding to this second binding site is based on reversed phase (RP), hydrophobic interaction (HIC) or hydrophilic interaction (HILIC). Linker sites, which can be represented by a chemical bond or by hydrophobic moieties like alkylene chains or hydrophilic moieties like amide structures connect the support to the binding domains and the binding domains among one another.