四重極型質量分析装置
    5.
    发明专利

    公开(公告)号:JPWO2012017548A1

    公开(公告)日:2013-09-19

    申请号:JP2012527517

    申请日:2010-08-06

    IPC分类号: H01J49/42 G01N27/62

    CPC分类号: H01J49/02 H01J49/4215

    摘要: イオン選択用の直流電圧を生成する直流電圧発生部(53)に与える制御パラメータとして、質量走査時に安定状態図上に描かれる走査直線の傾き及び位置を決める「ゲイン」及び「共通オフセット」のほかに、質量電荷比毎にオフセットを調整可能な「質量対応オフセット」を設ける。標準試料を利用した自動調整に際し、自動調整部(61)の制御の下に、「ゲイン」及び「共通オフセット」がまず決められた後に、質量分解能が略均一になるように各質量分解能に対する「質量対応オフセット」が決められ、それらは制御データ記憶部(52)に格納される。目的試料の分析時に四重極電圧制御部(51)は記憶部(52)から読み出した制御パラメータに従って直流電圧発生部(53)、高周波電圧発生部(54)を制御する。検波部(56)の非線形性のために高周波電圧Vが非線形になっても、その非線形に近似した折れ線状に直流電圧Uを変化させることができ質量分解能は略均一になる。

    Chromatograph mass analyzer
    7.
    发明专利
    Chromatograph mass analyzer 有权
    CHROMATOGRAPH质谱分析仪

    公开(公告)号:JP2012132799A

    公开(公告)日:2012-07-12

    申请号:JP2010285555

    申请日:2010-12-22

    发明人: SUMIYOSHI TAKASHI

    IPC分类号: G01N27/62 G01N30/72 G01N30/86

    CPC分类号: H01J49/02 G01N30/72 G01N30/86

    摘要: PROBLEM TO BE SOLVED: To prevent that many measurement events are overlapped in time and a measurement point time interval (loop time) becomes too long when an analysis condition table is automatically generated based on a compound table and acquire a chromatogram peak with successful accuracy and reproducibility.SOLUTION: After automatically generating an analysis condition table for measuring each compound according to a compound table (S1 to S3), loop time is calculated for every measurement section in which overlapping of measurement events is different (S4). When the loop time exceeds a specified value in a certain measurement section of a certain compound (No in S6), an event with the earliest end time and an event with the latest start time are extracted among the overlapping measurement events (S71), and intermediate time between the end time and the start time is calculated to adjust the length of each measurement event (S72 and S73). By repeating the process, a parameter in the analysis condition table is corrected so that the loop time becomes equal to or less than the specified value.

    摘要翻译: 要解决的问题:为了防止许多测量事件在时间上重叠,并且当基于复合表自动生成分析条件表并且获取色谱图峰值时,测量点时间间隔(循环时间)变得太长 成功的准确性和可重复性。 解决方案:根据复合表(S1至S3)自动生成用于测量每个化合物的分析条件表,计算测量事件重叠的每个测量部分的循环时间不同(S4)。 当某个化合物的某个测量部分中的循环时间超过指定值时(S6中的“否”),在重叠测量事件中提取具有最早结束时间的事件和具有最新开始时间的事件(S71),并且 计算结束时间和开始时间之间的中间时间,以调整每个测量事件的长度(S72和S73)。 通过重复该处理,校正分析条件表中的参数,使得循环时间变得等于或小于指定值。 版权所有(C)2012,JPO&INPIT

    Tandem type mass analyzing system and method
    10.
    发明专利
    Tandem type mass analyzing system and method 有权
    TANDEM类型质量分析系统和方法

    公开(公告)号:JP2007218692A

    公开(公告)日:2007-08-30

    申请号:JP2006038461

    申请日:2006-02-15

    IPC分类号: G01N27/62 G01N30/72

    CPC分类号: H01J49/02 H01J49/004

    摘要: PROBLEM TO BE SOLVED: To provide a tandem type mass analyzing system capable of performing fluctuation analysis with high efficiency by a tandem type mass analyzer. SOLUTION: A predetermined number of m/z regions are set, all of ions contained in the m/z regions are collectively separated at every m/z region and mass analysis is performed to acquire measured MS 2 data. The measured MS 2 data is compared with the reference MS 2 data stored in a reference database to detect the difference between both of them. Mass analysis not separating all of ions contained in the m/z region where a fluctuation component is detected is performed with respect to the m/z region to acquire measured MS 1 data and the measured MS 1 data is compared with reference MS 1 data to detect the difference between these data. Parent ions considered to be the cause of the fluctuation component are estimated from the difference and separated to perform mass analysis. COPYRIGHT: (C)2007,JPO&INPIT

    摘要翻译: 要解决的问题:提供一种能够通过串联式质量分析器以高效率进行波动分析的串联型质量分析系统。 解决方案:设置预定数量的m / z区域,m / z区域中包含的所有离子在每个m / z区域被共同分离,并进行质量分析以获得测量的MS SP>数据。 将测量的MS 2 数据与存储在参考数据库中的参考MS 2 数据进行比较,以检测它们之间的差异。 对于m / z区域进行不分离检测出波动成分的m / z区域中包含的所有离子的质量分析,得到测定的MS 1 数据,测定的MS 1 数据与参考MS 1 数据进行比较,以检测这些数据之间的差异。 被认为是波动成分的原因的父离子是从差异估计出来的,分离出来进行质量分析。 版权所有(C)2007,JPO&INPIT