Polynucleotides encoding the human citron kinase polypeptide, BMSNKC—0020/0021
    1.
    发明授权
    Polynucleotides encoding the human citron kinase polypeptide, BMSNKC—0020/0021 有权
    编码人柚子激酶多肽的多核苷酸BMSNKC-0020/0021

    公开(公告)号:US07326781B2

    公开(公告)日:2008-02-05

    申请号:US10412897

    申请日:2003-04-11

    IPC分类号: C07H21/04

    CPC分类号: C12N9/1205

    摘要: The present invention describes a novel human protein kinase related to citron kinase, and its encoding polynucleotide. Also described are expression vectors, host cells, antisense molecules, and antibodies associated with the protein kinase polynucleotide and/or polypeptide of this invention. In addition, methods for treating, diagnosing, preventing, and screening for disorders or diseases associated with abnormal biological activity of the protein kinase are described, as are methods for screening for modulators, e.g., agonists or antagonists, of the protein kinase activity and/or function.

    摘要翻译: 本发明描述了与柚子激酶相关的新型人蛋白激酶及其编码多核苷酸。 还描述了与本发明的蛋白激酶多核苷酸和/或多肽相关的表达载体,宿主细胞,反义分子和抗体。 此外,描述了用于治疗,诊断,预防和筛选与蛋白激酶的异常生物活性相关的疾病或疾病的方法,以及用于筛选蛋白激酶活性的调节剂例如激动剂或拮抗剂的方法和/ 或功能。