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公开(公告)号：US09084439B2
公开(公告)日：2015-07-21
申请号：US13240525
申请日：2011-09-22
申请人： Darrell Holton, Jr.
发明人： Darrell Holton, Jr.
摘要： The invention provides a smokeless tobacco product comprising a tobacco extract. In some embodiments, the smokeless tobacco product is translucent. The invention further provides methods for making and using the smokeless tobacco product. In certain embodiments, the smokeless tobacco product comprises isomalt, maltitol syrup, and a translucent tobacco extract prepared by ultrafiltration.
摘要翻译： 本发明提供了一种包含烟草提取物的无烟烟草制品。 在一些实施方案中，无烟烟草制品是半透明的。 本发明还提供了制造和使用无烟烟草制品的方法。 在某些实施方案中，无烟烟草制品包含异麦芽糖酮，麦芽糖醇糖浆和通过超滤制备的半透明烟草提取物。
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公开(公告)号：US20130098377A1
公开(公告)日：2013-04-25
申请号：US13278877
申请日：2011-10-21
IPC分类号： A61K31/465 , A24F23/02 , A61P25/00 , A61K31/785 , A61P25/34 , A24F47/00 , A61K9/14
CPC分类号： A61K9/0056 , A61K9/0043 , A61K9/0058 , A61K31/465
摘要： A composition intended to be employed for therapeutic purposes incorporates an active ingredient (e.g., a source of nicotine) and at a non-active ingredient that is carried by a porous substrate. The non-active ingredient can be a substance that has the capability of affecting the pH of the biological system to which it is applied (e.g., basic substance and/or buffering agent is sorbed onto the porous carrier, so as to be in intimate contact with that carrier). Representative forms of nicotine include free base (e.g., as a mixture of nicotine and microcrystalline cellulose), a nicotine salt (e.g., as nicotine bitartrate) and nicotine polacrilex. The basic substance can be sodium carbonate, and the porous substrate can be microcrystalline cellulose. The composition is useful for treatment of central nervous system conditions, diseases, and disorders, and can be used as a nicotine replacement therapy.
摘要翻译： 旨在用于治疗目的的组合物包含活性成分（例如，尼古丁来源）和由多孔底物携带的非活性成分。 非活性成分可以是具有影响其所施用的生物系统的pH的能力的物质（例如，碱性物质和/或缓冲剂被吸附到多孔载体上，以便紧密接触 与该承运人）。 尼古丁的代表性形式包括游离碱（例如，作为尼古丁和微晶纤维素的混合物），尼古丁盐（例如，作为酒石酸烟碱）和尼古丁polacrilex。 碱性物质可以是碳酸钠，多孔基材可以是微晶纤维素。 该组合物可用于治疗中枢神经系统疾病和疾病，并可用作尼古丁替代疗法。
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公开(公告)号：US20130074856A1
公开(公告)日：2013-03-28
申请号：US13614673
申请日：2012-09-13
申请人： Darrell Holton, JR.
发明人： Darrell Holton, JR.
CPC分类号： A24B13/00 , A23G3/48 , A24B15/24 , A24B15/245 , A24B15/30
摘要： A smokeless tobacco product is provided that includes a tobacco material in the form of a tobacco extract, a particulate tobacco material, or a combination thereof. In some embodiments, the smokeless tobacco product is substantially translucent. Methods for making and using the smokeless tobacco product are also provided. The smokeless tobacco product can include isomalt, maltitol syrup, particulate tobacco, and a translucent tobacco extract prepared by ultrafiltration.
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公开(公告)号：US20130074855A1
公开(公告)日：2013-03-28
申请号：US13240525
申请日：2011-09-22
申请人： Darrell Holton, JR.
发明人： Darrell Holton, JR.
摘要： The invention provides a smokeless tobacco product comprising a tobacco extract. In some embodiments, the smokeless tobacco product is translucent. The invention further provides methods for making and using the smokeless tobacco product. In certain embodiments, the smokeless tobacco product comprises isomalt, maltitol syrup, and a translucent tobacco extract prepared by ultrafiltration.
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公开(公告)号：US09907748B2
公开(公告)日：2018-03-06
申请号：US13278877
申请日：2011-10-21
IPC分类号： A61K31/465 , A61K9/00 , A61K9/68
CPC分类号： A61K9/0056 , A61K9/0043 , A61K9/0058 , A61K31/465
摘要： A composition intended to be employed for therapeutic purposes incorporates an active ingredient (e.g., a source of nicotine) and at a non-active ingredient that is carried by a porous substrate. The non-active ingredient can be a substance that has the capability of affecting the pH of the biological system to which it is applied (e.g., basic substance and/or buffering agent is sorbed onto the porous carrier, so as to be in intimate contact with that carrier). Representative forms of nicotine include free base (e.g., as a mixture of nicotine and microcrystalline cellulose), a nicotine salt (e.g., as nicotine bitartrate) and nicotine polacrilex. The basic substance can be sodium carbonate, and the porous substrate can be microcrystalline cellulose. The composition is useful for treatment of central nervous system conditions, diseases, and disorders, and can be used as a nicotine replacement therapy.
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公开(公告)号：US09474303B2
公开(公告)日：2016-10-25
申请号：US13614673
申请日：2012-09-13
申请人： Darrell Holton, Jr.
发明人： Darrell Holton, Jr.
CPC分类号： A24B13/00 , A23G3/48 , A24B15/24 , A24B15/245 , A24B15/30
摘要： A smokeless tobacco product is provided that includes a tobacco material in the form of a tobacco extract, a particulate tobacco material, or a combination thereof. In some embodiments, the smokeless tobacco product is substantially translucent. Methods for making and using the smokeless tobacco product are also provided. The smokeless tobacco product can include isomalt, maltitol syrup, particulate tobacco, and a translucent tobacco extract prepared by ultrafiltration.
摘要翻译： 提供了一种无烟烟草产品，其包括烟草提取物形式的烟草材料，烟草颗粒物质或其组合。 在一些实施方案中，无烟烟草制品基本上是半透明的。 还提供了制造和使用无烟烟草制品的方法。 无烟烟草产品可以包括异麦芽糖醇，麦芽糖醇糖浆，颗粒烟草，以及通过超滤制备的半透明烟草提取物。
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公开(公告)号：US20130078307A1
公开(公告)日：2013-03-28
申请号：US13240500
申请日：2011-09-22
申请人： Darrell Holton, JR. , Nelly Fransen , Matt Reddick
发明人： Darrell Holton, JR. , Nelly Fransen , Matt Reddick
IPC分类号： A61K31/465 , A61P25/00 , A61P25/34 , A61K31/787 , A61K9/14
CPC分类号： A61K47/26 , A23L27/10 , A23L27/2028 , A23L27/33 , A23L27/40 , A61K9/0056 , A61K9/20 , A61K9/7007 , A61K31/465
摘要： A composition intended to be employed for therapeutic purposes incorporates a nicotinic compound, a sugar substitute, and a sugar alcohol syrup. Representative forms of nicotine include free base (e.g., as a mixture of nicotine and microcrystalline cellulose), a nicotine salt (e.g., as nicotine bitartrate) or nicotine polacrilex. The composition is useful for treatment of central nervous system conditions, diseases, and disorders, and as a nicotine replacement therapy.
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公开(公告)号：US20080029110A1
公开(公告)日：2008-02-07
申请号：US11781604
申请日：2007-07-23
申请人： Michael Dube , Daniel Cantrell , John-Paul Mua , Darrell Holton , Cynthia Stokes , James Figlar
发明人： Michael Dube , Daniel Cantrell , John-Paul Mua , Darrell Holton , Cynthia Stokes , James Figlar
CPC分类号： A24B13/00 , A24B15/283
摘要： A smokeless tobacco product configured for insertion into the mouth of a user of the product is provided, the tobacco product including a water-permeable pouch containing a tobacco formulation, the tobacco formulation including a tobacco material and a plurality of microcapsules dispersed within the tobacco material, the plurality of microcapsules including an outer shell encapsulating an internal payload. The internal payload may include an additive such as water, flavorants, binders, colorants, pH adjusters, buffering agents, fillers, disintegration aids, humectants, antioxidants, oral care ingredients, preservatives, additives derived from herbal or botanical sources, and mixtures thereof. Microencapsulated flavorants include tobacco-containing flavorants, such as tobacco extracts or a particulate tobacco material, sweeteners (e.g., sweeteners containing neotame), and vanillin (optionally in a complexed form).
摘要翻译： 提供了构造成用于插入产品使用者的口中的无烟烟草产品，烟草制品包括含有烟草制剂的透水袋，烟草制剂包括烟草材料和分散在烟草材料内的多个微胶囊 ，所述多个微胶囊包括封装内部净荷的外壳。 内部有效载荷可以包括添加剂，例如水，调味剂，粘合剂，着色剂，pH调节剂，缓冲剂，填充剂，崩解助剂，保湿剂，抗氧化剂，口腔护理成分，防腐剂，来自草药或植物来源的添加剂，及其混合物。 微囊化香料包括含烟草的调味剂，例如烟草提取物或颗粒烟草材料，甜味剂（例如含有neotame的甜味剂）和香草醛（任选以络合形式）。
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公开(公告)号：US20070186941A1
公开(公告)日：2007-08-16
申请号：US11351919
申请日：2006-02-10
申请人： Darrell Holton , Daniel Cantrell
发明人： Darrell Holton , Daniel Cantrell
CPC分类号： A24B13/00 , A24B15/283
摘要： A smokeless tobacco product includes a powdered or granular smokeless tobacco formulation that is contained within a moisture-permeable packet or pouch. The smokeless tobacco formulation may include finely ground particles of tobacco in powder-like form and other ingredients such as sweeteners, binders, colorants, pH adjusters, fillers, flavoring ingredients, disintegration aids, antioxidants and preservatives. The tobacco formulation may have a dry or moist form. The container has the form of a pouch or bag, such as is the type commonly used for the manufacture of snus products. The container preferably contains at least one capsule, such as a spherical breakable capsule. The container is intended to be placed in the mouth of the tobacco user, such that the tobacco formulation within the container may be enjoyed by the user. After the tobacco user is finished using the smokeless tobacco product, the container is removed from the user's mouth for disposal. Alternatively, the container is dissolvable or dispersible in the mouth of the user.
摘要翻译： 无烟烟草制品包括粉末状或颗粒状无烟烟草制剂，其包含在透湿包装袋内。 无烟烟草制剂可以包括粉末状形式的细磨的烟草颗粒和其它成分如甜味剂，粘合剂，着色剂，pH调节剂，填充剂，调味成分，崩解助剂，抗氧化剂和防腐剂。 烟草制剂可以具有干燥或潮湿的形式。 容器具有袋或袋的形式，例如通常用于制造鼻塞产品的类型。 容器优选包含至少一个胶囊，例如球形可破坏胶囊。 该容器旨在放置在烟草使用者的口中，使得容器内的烟草制剂可以由使用者享用。 在烟草使用者完成使用无烟烟草制品之后，将容器从用户口中取出以便处理。 或者，容器可溶解或分散在使用者的口中。
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公开(公告)号：US20070062549A1
公开(公告)日：2007-03-22
申请号：US11233399
申请日：2005-09-22
申请人： Darrell Holton , Daniel Cantrell , James Figlar
发明人： Darrell Holton , Daniel Cantrell , James Figlar
IPC分类号： A24B15/00
摘要： A smokeless tobacco product includes a powdered or granular smokeless tobacco formulation that is contained within a moisture-permeable packet or pouch. The smokeless tobacco formulation includes finely ground particles of tobacco in powder-like form and other ingredients such as sweeteners, binders, colorants, pH adjusters, fillers, flavoring agents, disintegration aids, antioxidants and preservatives. The container has the form of a pouch or bag, such as is the type commonly for the manufacture of snus products. The container is intended to be placed in the mouth of the tobacco user, in order that the dry tobacco formulation within the container may be enjoyed by the user. After the tobacco user is finished using the smokeless tobacco product, the container is removed from the user's mouth for disposal. Alternatively, the container is dissolvable or dispersible in the mouth of the user.
摘要翻译： 无烟烟草制品包括粉末状或颗粒状无烟烟草制剂，其包含在透湿包装袋内。 无烟烟草制剂包括粉末状烟草的精细研磨颗粒和其它成分如甜味剂，粘合剂，着色剂，pH调节剂，填充剂，调味剂，崩解助剂，抗氧化剂和防腐剂。 容器具有袋或袋的形式，例如通常用于制造鼻塞产品的类型。 该容器旨在放置在烟草使用者的口中，以便容器内的干烟草制剂可由使用者享用。 在烟草使用者完成使用无烟烟草制品之后，将容器从用户口中取出以便处理。 或者，容器可溶解或分散在使用者的口中。
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