公开(公告)号：US12251684B2

公开(公告)日：2025-03-18

申请号：US18438255

申请日：2024-02-09

Applicant: Korea Research Institute of Chemical Technology

Inventor： Ho Jeong Chae ,  Youngmin Kim ,  Thien An Le ,  Jeong-Rang Kim ,  Tae Wan Kim

IPC: B01J23/63 ,  B01J23/10 ,  B01J37/02 ,  B01J37/03 ,  B01J37/10 ,  C01B3/04

Abstract: The present disclosure relates to a catalyst for ammonia decomposition, a manufacturing method therefor, and a method for producing hydrogen using the same. More particularly, the present disclosure relates to a catalyst for ammonia decomposition, a manufacturing method therefor, and a method for producing hydrogen using the same, in which by manufacturing a catalyst for decomposition of ammonia using a solvothermal synthesis method to which alcohol is applied, an ammonia conversion rate can be improved due to excellent catalytic activity in an ammonia decomposition reaction, and hydrogen can be efficiently produced from ammonia due to long-term stability even at a high temperature and for long periods of time.

公开(公告)号：US12247175B2

公开(公告)日：2025-03-11

申请号：US18026897

申请日：2021-08-25

Applicant: KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY ,  RESEARCH INSTITUTE OF INDUSTRIAL SCIENCE & TECHNOLOGY

Inventor： Sunyoung Park ,  Pill Won Seo ,  Ki Hyuk Kang ,  Narae Kang ,  Gyoo Tae Kim ,  Chi Woong Ahn ,  Joon Woo Kim ,  Dong Jun Koh

IPC: C10G9/00 ,  C10G55/04

Abstract: The present invention relates to a method for upgrading heavy oil by using byproducts of coke production, and particularly provides a method for upgrading heavy oil comprising the steps of: a) mixing heavy oil with byproducts of coke production to produce a mixed liquid: and b) subjecting the mixed liquid to pyrolysis, the method allowing reduction of the amount of coke generated and thus being economical and effective.

公开(公告)号：US20250059148A1

公开(公告)日：2025-02-20

申请号：US18701820

申请日：2022-10-20

Applicant: KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY

Inventor： Dong Won HWANG ,  In Yong EOM ,  Young Kyu HWANG ,  Ma Eum LEE

IPC: C07D307/48

Abstract: According to the present disclosure, by forming normal pressure conditions in a reaction system through application of a reflux system to an aqueous phase in the presence of sulfuric acid and an inorganic salt in the dehydration reaction of biomass-derived sugar components in an open system, there is no need to include a high-pressure vessel required in a conventional 5-halomethylfurfural production process, there is no risk of safety accidents, including the explosion of a high-pressure vessel and the leakage of strong acid gas, and there is a remarkable effect in that yield is improved three-fold or more compared to the case of using a conventionally used acid catalyst under the normal pressure conditions.

公开(公告)号：US20250051491A1

公开(公告)日：2025-02-13

申请号：US18710904

申请日：2023-03-27

Applicant: KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY

Inventor： Dong Won HWANG ,  Changho YOO ,  Seung Hyeok CHA ,  Gwang Nam YUN

IPC: C08F4/78 ,  C08F110/02

Abstract: The present invention pertains to: an ethylene oligomerization catalyst containing a ligand compound; a catalyst composition employing same; and a method for producing an ethylene oligomer by using same. The catalyst exhibits excellent selectivity to oligomers and selectivity to 1-hexane, thus making it possible to mass-produce 1-hexane, which is an industrially useful chemical raw material, with high purity.

公开(公告)号：US12202876B2

公开(公告)日：2025-01-21

申请号：US17296622

申请日：2019-12-16

Applicant: KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY

Inventor： Seong Jun Kim ,  Kyun Do Kim ,  In Su Hwang ,  Keunbon Ku ,  Chonsaeng Kim ,  Bum Tae Kim ,  Dae Gyun Ahn ,  Hae Soo Kim ,  Young Chan Kwon

IPC: C07K14/705 ,  A61K47/64

Abstract: The present invention relates to a transmembrane domain derived from human LRRC24 protein. More specifically, the present invention relates to a transmembrane domain derived from the human LRRC24 protein (LRRC24P transmembrane domain) or a cell-penetrating peptide, and an intracellular delivery system comprising same. The transmembrane domain derived from the human LRRC24 protein of the present invention can be used to deliver cargo materials such as compounds, biomolecules, and various polymer materials into cells. Since the LRRC24P transmembrane domain of the present invention exhibits higher cell penetration efficiency compared to conventional cell-penetrating peptides and is derived from human proteins, thus avoiding side effects and immune responses caused by peptides derived from foreign proteins, it can be usefully used as an effective intracellular delivery method for compounds, biomolecules, and various polymer materials applied to the human body.

公开(公告)号：US20250018357A1

公开(公告)日：2025-01-16

申请号：US18687504

申请日：2022-08-02

Applicant: KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY

Inventor： Yong Tae KIM ,  Sung Woo LEE ,  Jungho SHIN ,  Seung Ju HAN ,  Tsegay Gebrekidan GEBREYOHANNES

IPC: B01J19/02 ,  B01J19/24 ,  C07C2/74

Abstract: The present invention relates to a nonoxidative methane direct converting reactor and a preparation method of ethylene and aromatic compound using the same and, more specifically, to a nonoxidative methane direct converting reactor and a preparation method of ethylene and aromatic compound using the same, wherein the reactor maximizes a catalytic reaction rate, minimizes cokes production, and provides a high conversion rate of methane and a high yield of ethylene and an aromatic compound even at a low hydrogen supply ratio in the production of ethylene and an aromatic compound from methane.

公开(公告)号：US12161722B2

公开(公告)日：2024-12-10

申请号：US18573904

申请日：2022-06-24

Applicant: KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY ,  UBIX THERAPEUTICS, INC.

Inventor： Pil Ho Kim ,  Sung Yun Cho ,  Jae Du Ha ,  Chi Hoon Park ,  Jong Yeon Hwang ,  Hyun Jin Kim ,  Song Hee Lee ,  Ye Seul Lim ,  Han Wool Kim ,  Sun Mi Yoo ,  Beom Seon Suh ,  Ji Youn Park ,  Je Ho Ryu ,  Jung Min Ahn ,  Hee Jung Moon ,  Ho Hyun Lee

IPC: A61K47/55 ,  A61K47/54 ,  A61K47/60

Abstract: The present invention relates to a novel heterocyclic compound and a composition, for preventing or treating a cancer, an autoimmune disease, and an inflammatory disease, comprising same. The novel heterocyclic compound of the present invention is a bifunctional compound having a Bruton's tyrosine kinase (BTK) degradation function via a ubiquitin proteasome pathway, and may be utilized as a composition for preventing or treating a cancer, an autoimmune disease, and Parkinson's disease.

公开(公告)号：US12146155B2

公开(公告)日：2024-11-19

申请号：US18547750

申请日：2021-04-21

Applicant: KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY

Inventor： Han-Jin Park ,  Hyemin Kim ,  Ilkyun Im ,  Ji-Woo Kim

IPC: C12N5/00 ,  C12N5/0735

Abstract: The present invention relates to a method for constructing a human pluripotent stem cell-derived liver organoid having enhanced drug metabolic potentials and a liver organoid constructed by the method. Because differentiation is made from human induced pluripotent stem cells dedifferentiated from somatic cells of patients, the cells are easily supplied so that patient-specific liver organoids can be prepared. The organoids can similarly simulate the real human liver structure because they consist of hepatocytes, cholangiocytes, gallbladder cells, and microduct structures, have excellent expression and functions of drug metabolism enzymes, and exhibit drug toxicity, drug metabolic capability, and drug-induced cardiotoxicity. Thus, the organoids can be advantageously used as liver models for searching for pathogenesis of liver diseases and for evaluating drug stability.

公开(公告)号：US20240375947A1

公开(公告)日：2024-11-14

申请号：US18688233

申请日：2022-08-30

Applicant: KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY

Inventor： Ho Jeong CHAE ,  Youngmin KIM ,  Jeong-Rang KIM ,  Do Quoc CUONG ,  Geo Jong KIM ,  Tae Wan KIM

IPC: C01B3/04 ,  B01J21/04 ,  B01J23/755 ,  B01J23/889 ,  B01J37/03 ,  B01J37/04 ,  B01J37/06 ,  B01J37/08 ,  B01J37/16

Abstract: The present invention pertains to: a method for preparing a catalyst for ammonia decomposition using cation-anion double hydrolysis; the catalyst; and a method for producing hydrogen through ammonia decomposition using the catalyst, wherein a catalyst for ammonia decomposition for hydrogen production, in which nickel (Ni) is supported on an aluminum oxide support or an aluminum composite oxide support doped with a promoter metal (M), is prepared using a ONE POT cation-anion double hydrolysis (CADH) method.

公开(公告)号：US20240367154A1

公开(公告)日：2024-11-07

申请号：US18044942

申请日：2021-09-07

Applicant: Korea Research Institute of Chemical Technology

Inventor： Ho Jeong Chae ,  Youngmin Kim ,  Thien An Le ,  Jeong-Rang Kim ,  Tae Wan Kim ,  You Jin Lee ,  Su Un Lee

IPC: B01J23/10 ,  B01J23/63 ,  B01J35/30 ,  B01J35/40 ,  B01J35/50 ,  B01J35/51 ,  C01B3/04

Abstract: A catalyst for an ammonia decomposition reaction and a hydrogen production method using the catalyst are proposed. The shape of cerium oxide used as a catalyst carrier for the catalyst is controlled, and cesium (Cs) is included in the catalyst as a catalyst enhancer. Thus, the catalyst increases an ammonia conversion rate and has improved long-term stability.