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1.发明授权公开(公告)号：US08163743B2
公开(公告)日：2012-04-24
申请号：US12994246
申请日：2009-06-03
申请人： Ian Robert Baldwin , Kenneth David Down , Paul Faulder , Simon Gaines , Julie Nicole Hamblin , Katherine Louise Jones , Joelle Le , Christopher James Lunniss , Nigel James Parr , Timothy John Ritchie , Christian Alan Paul Smethurst , Yoshiaki Washio
发明人： Ian Robert Baldwin , Kenneth David Down , Paul Faulder , Simon Gaines , Julie Nicole Hamblin , Katherine Louise Jones , Joelle Le , Christopher James Lunniss , Nigel James Parr , Timothy John Ritchie , Christian Alan Paul Smethurst , Yoshiaki Washio
IPC分类号： C07D231/56 , C07D401/04 , A61K31/416 , A61K31/4439 , A61P11/00
CPC分类号： C07D231/56
摘要： The invention is directed to certain novel compounds. Specifically, the invention is directed to compounds of formula (I) and salts thereof. The compounds of the invention are inhibitors of P13-kinase activity.
摘要翻译： 本发明涉及某些新化合物。 具体地，本发明涉及式（I）的化合物及其盐。 本发明的化合物是P13-激酶活性的抑制剂。
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公开(公告)号：US08658635B2
公开(公告)日：2014-02-25
申请号：US12994250
申请日：2009-06-03
申请人： Ian Robert Baldwin , Kenneth David Down , Paul Faulder , Simon Gaines , Julie Nicole Hamblin , Joelle Le , Christopher James Lunniss , Nigel James Parr , Timothy John Ritchie , John Edward Robinson , Juliet Kay Simpson , Christian Alan Paul Smethurst
发明人： Ian Robert Baldwin , Kenneth David Down , Paul Faulder , Simon Gaines , Julie Nicole Hamblin , Joelle Le , Christopher James Lunniss , Nigel James Parr , Timothy John Ritchie , John Edward Robinson , Juliet Kay Simpson , Christian Alan Paul Smethurst
IPC分类号： A61K31/55 , A61K31/5377 , A61K31/501 , A61K31/496 , A61K31/497 , A61K31/50 , A61K31/505 , A61K31/4523 , A61K31/4427 , A61K31/427 , A61K31/425 , C07D267/02 , C07D279/12 , C07D295/00 , C07D265/30 , C07D413/14 , C07D487/12 , C07D417/12 , C07D211/00 , C07D277/20 , C07D235/00 , C07D233/54 , C07D403/14
CPC分类号： C07D231/56
摘要： The invention is directed to certain novel compounds of formula (I) and salts thereof. The compounds of the invention are inhibitors of PI3-kinase activity.
摘要翻译： 本发明涉及某些新的式（I）化合物及其盐。 本发明的化合物是PI3-激酶活性的抑制剂。
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公开(公告)号：US08536169B2
公开(公告)日：2013-09-17
申请号：US12994254
申请日：2009-06-03
申请人： Ian Robert Baldwin , Kenneth David Down , Paul Faulder , Simon Gaines , Joelle Le , Nigel James Parr , Timothy John Ritchie , Juliet Kay Simpson , Christian Alan Paul Smethurst
发明人： Ian Robert Baldwin , Kenneth David Down , Paul Faulder , Simon Gaines , Joelle Le , Nigel James Parr , Timothy John Ritchie , Juliet Kay Simpson , Christian Alan Paul Smethurst
IPC分类号： A61K31/5377 , A61K31/416 , A61K31/454 , A61K31/4439 , C07D401/14 , C07D403/04 , C07D413/14
CPC分类号： C07D403/04 , C07D401/14 , C07D403/14 , C07D413/14 , C07D471/04
摘要： The invention is directed to certain novel compounds directed to compounds of formula (I) and salts thereof. The compounds of the invention are inhibitors of PI3-kinase activity.
摘要翻译： 本发明涉及针对式（I）化合物及其盐的某些新化合物。 本发明的化合物是PI3-激酶活性的抑制剂。
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公开(公告)号：US20130165433A1
公开(公告)日：2013-06-27
申请号：US13821594
申请日：2011-09-06
申请人： Ian Robert Baldwin , Kenneth David Down , Paul Faulder , Simon Gaines , Julie Nicole Hamblin , Zoe Alicia Harrison , Katherine Louise Jones , Paul Spencer Jones , Suzanne Elaine Keeling , Joelle Le , Christopher James Lunniss , Charlotte Jane Mitchell , Nigel James Parr , Timothy John Ritchie , John Edward Robinson , Juliet Kay Simpson , Christopher Alan Paul Smethurst , Yoshiaki Washio
发明人： Ian Robert Baldwin , Kenneth David Down , Paul Faulder , Simon Gaines , Julie Nicole Hamblin , Zoe Alicia Harrison , Katherine Louise Jones , Paul Spencer Jones , Suzanne Elaine Keeling , Joelle Le , Christopher James Lunniss , Charlotte Jane Mitchell , Nigel James Parr , Timothy John Ritchie , John Edward Robinson , Juliet Kay Simpson , Christopher Alan Paul Smethurst , Yoshiaki Washio
IPC分类号： C07D413/14
CPC分类号： A61K31/5377 , A61K31/416 , A61K31/422 , A61K31/4245 , A61K31/427 , A61K31/437 , A61K31/4439 , A61K31/454 , A61K31/496 , A61K31/5386 , C07D413/14
摘要： The present invention is directed to compounds for use in the treatment or prevention of influenza virus infection.
摘要翻译： 本发明涉及用于治疗或预防流感病毒感染的化合物。
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公开(公告)号：US20120245171A1
公开(公告)日：2012-09-27
申请号：US13513063
申请日：2010-12-03
申请人： Ian Robert Baldwin , Kenneth David Down , Paul Faulder , Simon Gaines , Julie Nicole Hamblin , Katherine Louise Jones , Paul Spencer Jones , Joelle Le , Christopher James Lunniss , Nigel James Parr , Timothy John Ritchie , John Edward Robinson , Juliet Kay Simpson , Christian Alan Paul Smethurst
发明人： Ian Robert Baldwin , Kenneth David Down , Paul Faulder , Simon Gaines , Julie Nicole Hamblin , Katherine Louise Jones , Paul Spencer Jones , Joelle Le , Christopher James Lunniss , Nigel James Parr , Timothy John Ritchie , John Edward Robinson , Juliet Kay Simpson , Christian Alan Paul Smethurst
IPC分类号： A61K31/4985 , C07D417/14 , A61K31/496 , C07D413/14 , A61K31/5377 , C07D471/04 , A61P37/00 , A61P29/00 , A61P9/00 , A61P35/00 , A61P25/28 , A61P1/18 , A61P13/12 , A61P7/04 , A61P15/08 , A61P37/06 , A61P11/00 , A61P25/00 , A61P11/06 , A61P37/08 , A61P17/00 , A61P1/00 , A61P7/02 , A61P9/10 , C07D487/04
CPC分类号： C07D487/04 , C07D401/04 , C07D401/14 , C07D405/14 , C07D417/04 , C07D471/04
摘要： The invention is directed to certain novel compounds. Specifically, the invention is directed to compounds of formula (I): and salts thereof. The compounds of the invention are inhibitors of PI3-kinase activity.
摘要翻译： 本发明涉及某些新化合物。 具体地，本发明涉及式（I）的化合物及其盐。 本发明的化合物是PI3-激酶活性的抑制剂。
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公开(公告)号：US20110183973A1
公开(公告)日：2011-07-28
申请号：US12994254
申请日：2009-06-03
申请人： Ian Robert Baldwin , Kenneth David Down , Paul Faulder , Simon Gaines , Julie Nicole Hamblin , Paul Spencer Jones , Joelle Le , Nigel James Parr , Timothy John Ritchie , John Edward Robinson , Juliet Kay Simpson , Christian Alan Paul Smethurst
发明人： Ian Robert Baldwin , Kenneth David Down , Paul Faulder , Simon Gaines , Julie Nicole Hamblin , Paul Spencer Jones , Joelle Le , Nigel James Parr , Timothy John Ritchie , John Edward Robinson , Juliet Kay Simpson , Christian Alan Paul Smethurst
IPC分类号： A61K31/5377 , C07D231/56 , A61K31/416 , C07D401/14 , A61K31/454 , C07D413/14 , A61K31/4439 , A61P35/00 , A61P3/00 , A61P7/00 , A61P11/00 , A61P19/00 , A61P25/04 , A61P29/00 , A61P37/06
CPC分类号： C07D403/04 , C07D401/14 , C07D403/14 , C07D413/14 , C07D471/04
摘要： The invention is directed to certain novel compounds directed to compounds of formula (I) and salts thereof. The compounds of the invention are inhibitors of PI3-kinase activity.
摘要翻译： 本发明涉及针对式（I）化合物及其盐的某些新化合物。 本发明的化合物是PI3-激酶活性的抑制剂。
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公开(公告)号：US20110118246A1
公开(公告)日：2011-05-19
申请号：US12994253
申请日：2009-06-03
申请人： Ian Robert Baldwin , Kenneth David Down , Paul Faulder , Simon Gaines , Julie Nicole Hamblin , Joelle Le , Christopher James Lunniss , Nigel James Parr , Timothy John Ritchie , Juliet Kay Simpson , Christian Alan Paul Smethurst
发明人： Ian Robert Baldwin , Kenneth David Down , Paul Faulder , Simon Gaines , Julie Nicole Hamblin , Joelle Le , Christopher James Lunniss , Nigel James Parr , Timothy John Ritchie , Juliet Kay Simpson , Christian Alan Paul Smethurst
IPC分类号： A61K31/4439 , C07D401/14 , C07D413/14 , A61K31/5377 , A61K31/4545 , A61K31/496 , C07D405/14 , C07D471/04 , A61K31/4985 , A61K31/444 , C07D417/14 , A61K31/541 , A61P11/00 , A61P11/06 , A61P25/28 , A61P35/00 , A61P37/06 , A61P29/00 , A61P9/10
CPC分类号： C07D401/14 , C07D405/14 , C07D413/14 , C07D471/04
摘要： The invention is directed to to compounds of formula (I) and salts thereof. The compounds of the invention are inhibitors of PI3-kinase activity.
摘要翻译： 本发明涉及式（I）化合物及其盐。 本发明的化合物是PI3-激酶活性的抑制剂。
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8.发明申请公开(公告)号：US20110112070A1
公开(公告)日：2011-05-12
申请号：US12994246
申请日：2009-06-03
申请人： Ian Robert Baldwin , Kenneth David Down , Paul Faulder , Simon Gaines , Julie Nicole Hamblin , Katherine Louise Jones , Joelle Le , Christopher James Lunniss , Nigel James Parr , Timothy John Ritchie , Christian Alan Paul Smethurst , Yoshiaki Washio
发明人： Ian Robert Baldwin , Kenneth David Down , Paul Faulder , Simon Gaines , Julie Nicole Hamblin , Katherine Louise Jones , Joelle Le , Christopher James Lunniss , Nigel James Parr , Timothy John Ritchie , Christian Alan Paul Smethurst , Yoshiaki Washio
IPC分类号： A61K31/416 , C07D401/12 , C07D231/56 , C07D417/14 , C07D417/12 , C07D413/14 , A61K31/4439 , A61K31/427 , A61K31/5377 , A61K31/496 , A61K31/4545 , A61K31/541 , A61K31/553 , A61P11/00
CPC分类号： C07D231/56
摘要： The invention is directed to certain novel compounds. Specifically, the invention is directed to compounds of formula (I) and salts thereof. The compounds of the invention are inhibitors of P13-kinase activity.
摘要翻译： 本发明涉及某些新化合物。 具体地，本发明涉及式（I）的化合物及其盐。 本发明的化合物是P13-激酶活性的抑制剂。
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公开(公告)号：US08765743B2
公开(公告)日：2014-07-01
申请号：US12994253
申请日：2009-06-03
申请人： Ian Robert Baldwin , Kenneth David Down , Paul Faulder , Simon Gaines , Julie Nicole Hamblin , Joelle Le , Christopher James Lunniss , Nigel James Parr , Timothy John Ritchie , Juliet Kay Simpson , Christian Alan Paul Smethurst
发明人： Ian Robert Baldwin , Kenneth David Down , Paul Faulder , Simon Gaines , Julie Nicole Hamblin , Joelle Le , Christopher James Lunniss , Nigel James Parr , Timothy John Ritchie , Juliet Kay Simpson , Christian Alan Paul Smethurst
IPC分类号： A61K31/4439 , A61K31/5377 , A61K31/4545 , A61K31/496 , C07D401/14 , C07D413/14 , C07D405/14 , C07D471/04
CPC分类号： C07D401/14 , C07D405/14 , C07D413/14 , C07D471/04
摘要： The invention is directed to compounds of formula (I) and salts thereof. The compounds of the invention are inhibitors of PI3-kinase activity.
摘要翻译： 本发明涉及式（I）的化合物及其盐。 本发明的化合物是PI3-激酶活性的抑制剂。
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公开(公告)号：US20120238571A1
公开(公告)日：2012-09-20
申请号：US13513079
申请日：2010-12-03
申请人： Ian Robert Baldwin , Kenneth David Down , Paul Faulder , Simon Gaines , Julie Nicole Hamblin , Katherine Louise Jones , Joelle Le , Christopher James Lunniss , Nigel James Parr , Timothy John Ritchie , John Edward Robinson , Christian Alan Paul Smethurst
发明人： Ian Robert Baldwin , Kenneth David Down , Paul Faulder , Simon Gaines , Julie Nicole Hamblin , Katherine Louise Jones , Joelle Le , Christopher James Lunniss , Nigel James Parr , Timothy John Ritchie , John Edward Robinson , Christian Alan Paul Smethurst
IPC分类号： C07D417/14 , A61K31/437 , A61K31/4439 , A61K31/427 , C07D413/14 , C07D471/04 , A61P11/00 , A61P37/08 , A61P37/00 , A61P29/00 , A61P9/00 , A61P25/28 , A61P1/18 , A61P13/12 , A61P35/00 , A61P15/00 , A61P41/00 , A61P25/00 , A61P11/06 , A61P19/02 , A61P1/00 , A61P9/10 , A61K31/5377
CPC分类号： C07D417/14 , C07D417/12 , C07D471/04
摘要： The invention is directed to certain novel compounds. Specifically, the invention is directed to compounds of formula (I): and salts thereof. The compounds of the invention are inhibitors of PI3-kinase activity.
摘要翻译： 本发明涉及某些新化合物。 具体地，本发明涉及式（I）的化合物及其盐。 本发明的化合物是PI3-激酶活性的抑制剂。
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