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公开(公告)号:US07598078B2
公开(公告)日:2009-10-06
申请号:US11105725
申请日:2005-04-14
申请人: Menzo Jans Havenga , Lennart Holterman , Stefan Kostense , Maria Grazia Pau , Mieke C. Sprangers , Ronald Vogels
发明人: Menzo Jans Havenga , Lennart Holterman , Stefan Kostense , Maria Grazia Pau , Mieke C. Sprangers , Ronald Vogels
CPC分类号: C12N7/00 , A61K48/00 , A61K2039/5256 , A61K2039/545 , C07K14/005 , C12N15/86 , C12N2710/10343 , C12N2710/24143 , C12N2740/15034 , C12N2760/18434 , Y02A50/394 , Y02A50/412
摘要: The present invention provides new uses of recombinant adenoviral vectors in vaccination regimens, such as prime/boost set-ups and subsequent vaccinations and applications for gene therapy. Moreover, the invention provides new assays to determine the best regimen for applying the most suitable recombinant viral vector in a vaccination or gene therapy setting.
摘要翻译: 本发明提供重组腺病毒载体在疫苗接种方案中的新用途,例如初次/加强装置和随后的疫苗接种和基因治疗的应用。 此外,本发明提供了新的测定法以确定在接种或基因治疗设置中应用最合适的重组病毒载体的最佳方案。