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    INTEGRATED SECURITY NETWORK
    1.
    发明申请
    INTEGRATED SECURITY NETWORK 审中-公开

    公开(公告)号：US20190272720A1

    公开(公告)日：2019-09-05

    申请号：US16371928

    申请日：2019-04-01

    Applicant: David Stuart Wilson ,  Andrew Wilson

    Inventor： David Stuart Wilson ,  Andrew Wilson

    IPC: G08B13/196 ,  G08B25/00 ,  H04L9/00 ,  G08B25/14

    Abstract: A security system architecture and method of operation that combines a local security network with control panel and sensors, a central monitoring station (CMS), and a separate operator computer server that provides a web portal for both the homeowner and CMS, that maintains a persistent connection between the control panel and CMS allowing failsafe dual-path signaling. This dual-path signaling technique is extended to provide an effective “smash and grab alarm”, and various approaches to dual-path signal management are disclosed including handshaking, persistent domain monitoring, relayed Operator 3-to-CMS signaling, etc. Improved processes for remotely accessing video are also disclosed along with an improved process for remote control panel configuration, and control panel interfacing with home automation appliances.

    Purine derivatives
    2.
    发明授权
    Purine derivatives 有权
    嘌呤衍生物

    公开(公告)号：US08846696B2

    公开(公告)日：2014-09-30

    申请号：US12489663

    申请日：2009-06-23

    Applicant: Peter Martin Fischer ,  Michael Jarman ,  Edward McDonald ,  Bernard Nutley ,  Florence Raynaud ,  Stuart Wilson ,  Paul Workman

    Inventor： Peter Martin Fischer ,  Michael Jarman ,  Edward McDonald ,  Bernard Nutley ,  Florence Raynaud ,  Stuart Wilson ,  Paul Workman

    IPC: A61K31/52 ,  C07D473/16

    CPC classification number: C07D473/16 ,  A61K31/52 ,  Y02A50/411

    Abstract: The present invention relates to compounds of formula 1 or pharmaceutically acceptable salts thereof, wherein one of R1 and R2 is methyl, ethyl or isopropyl, and the other is H; R3 and R4 are each independently H, branched or unbranched C1-C6 alkyl, or aryl, and wherein at least one of R3 and R4 is other than H; R5 is a branched or unbranched C1-C5 alkyl group or a C1-C6 cycloalkyl group, each of which may be optionally substituted with one or more OH groups; R6, R7, R8 and R9 are each independently H, halogen, NO2, OH, OMe, CN, NH2, COOH, CONH2, or SO2NH2. A further aspect of the invention relates to pharmaceutical compositions comprising compounds of formula 1, and the use of said compounds in treating proliferative disorders, viral disorders, stroke, alopecia, CNS disorders, neurodegenerative disorders, or diabetes.

    Abstract translation: 本发明涉及式1化合物或其药学上可接受的盐，其中R 1和R 2之一是甲基，乙基或异丙基，另一个是H; R 3和R 4各自独立地为H，支链或非支链的C 1 -C 6烷基或芳基，并且其中R 3和R 4中的至少一个不是H; R5是支链或非支链C 1 -C 5烷基或C 1 -C 6环烷基，其各自可以任选被一个或多个OH基取代; R6，R7，R8和R9各自独立地为H，卤素，NO2，OH，OMe，CN，NH2，COOH，CONH2或SO2NH2。 本发明的另一方面涉及包含式1化合物的药物组合物，以及所述化合物在治疗增殖性疾病，病毒性疾病，中风，脱发，中枢神经系统疾病，神经变性疾病或糖尿病中的用途。

    Purine derivatives
    3.
    发明授权
    Purine derivatives 有权
    嘌呤衍生物

    公开(公告)号：US07544689B2

    公开(公告)日：2009-06-09

    申请号：US11238533

    申请日：2005-09-28

    Applicant: Peter Martin Fischer ,  Michael Jarman ,  Edward McDonald ,  Bernard Nutley ,  Florence Raynaud ,  Stuart Wilson ,  Paul Workman

    Inventor： Peter Martin Fischer ,  Michael Jarman ,  Edward McDonald ,  Bernard Nutley ,  Florence Raynaud ,  Stuart Wilson ,  Paul Workman

    IPC: C07D473/16 ,  A61K31/52 ,  A61P35/00 ,  A61P3/10 ,  A61P31/20 ,  A61P31/14 ,  A61P17/06 ,  A61P35/02 ,  A61P25/28

    CPC classification number: C07D473/16

    Abstract: The present invention relates to compounds of formula I or pharmaceutically acceptable salts thereof, wherein one of R1 and R2 is methyl, ethyl or isopropyl, and the other is H; R3 and R4 are each independently H, branched or un branched C1-C6 alkyl, or aryl, and wherein at least one of R3 and R4 is other than H; R5 is a branched or unbranched C1-C5 alkyl group or a C1-C6 cycloalkyl group, each of which may be optionally substituted with one or more OH groups; R6, R7, R8 and R9 are each independently H, halogen, NO2, OH, OMe, CN, NH2, COOH, CONH2, or SO2NH2. A further aspect of the invention relates to pharmaceutical compositions comprising compounds of formula 1, and the use of said compounds in treating proliferative disorders, viral disorders, CNS disorders, diabetes, stroke, alopecia or neurodegenerative disorders.

    Abstract translation: 本发明涉及式I化合物或其药学上可接受的盐，其中R 1和R 2之一是甲基，乙基或异丙基，另一个是H; R 3和R 4各自独立地为H，支链或非支链C 1 -C 6烷基或芳基，并且其中R 3和R 4中的至少一个不是H; R5是支链或非支链C 1 -C 5烷基或C 1 -C 6环烷基，其各自可以任选被一个或多个OH基取代; R6，R7，R8和R9各自独立地为H，卤素，NO2，OH，OMe，CN，NH2，COOH，CONH2或SO2NH2。 本发明的另一方面涉及包含式1化合物的药物组合物，以及所述化合物在治疗增殖性疾病，病毒性疾病，中枢神经系统疾病，糖尿病，中风，脱发或神经变性疾病中的用途。

    Methods and kits for detecting an enzyme capable of modifying a nucleic acid
    4.
    发明申请
    Methods and kits for detecting an enzyme capable of modifying a nucleic acid 审中-公开
    用于检测能够修饰核酸的酶的方法和试剂盒

    公开(公告)号：US20060257879A1

    公开(公告)日：2006-11-16

    申请号：US10566792

    申请日：2004-08-02

    Applicant: Stuart Wilson ,  Christopher Stanley ,  Sharon Banin

    Inventor： Stuart Wilson ,  Christopher Stanley ,  Sharon Banin

    IPC: C12Q1/68 ,  C12Q1/34

    CPC classification number: C12Q1/42 ,  C12Q1/6806 ,  G01N33/573 ,  G01N33/57434

    Abstract: The present invention provides a method of detecting an enzyme in a sample wherein the enzyme is capable of adding or removing a chemical moiety to or from a nucleic acid molecule, which thereby confers altered sensitivity of the nucleic acid molecule in a subsequent process. The invention also relates to diagnostic methods which take advantage of the method of the invention and kits which are useful for carrying out the method of the invention.

    Abstract translation: 本发明提供了一种检测样品中的酶的方法，其中酶能够向或从核酸分子添加或除去化学部分，从而赋予核酸分子在随后的方法中更高的敏感性。 本发明还涉及利用本发明方法和可用于实施本发明方法的试剂盒的诊断方法。

    New purine derivatives
    5.
    发明申请
    New purine derivatives 有权
    新嘌呤衍生物

    公开(公告)号：US20050256142A1

    公开(公告)日：2005-11-17

    申请号：US11033692

    申请日：2005-01-11

    Applicant: Peter Fischer ,  Michael Jarman ,  Edward McDonald ,  Bernard Nutley ,  Florence Raynaud ,  Stuart Wilson ,  Paul Workman

    Inventor： Peter Fischer ,  Michael Jarman ,  Edward McDonald ,  Bernard Nutley ,  Florence Raynaud ,  Stuart Wilson ,  Paul Workman

    IPC: A61K31/52 ,  A61P3/10 ,  A61P9/00 ,  A61P17/06 ,  A61P17/14 ,  A61P25/28 ,  A61P31/12 ,  A61P35/00 ,  C07D473/16 ,  C07D473/12

    CPC classification number: C07D473/16 ,  A61K31/52 ,  Y02A50/411

    Abstract: The present invention relates to compounds of formula 1 or pharmaceutically acceptable salts thereof, wherein one of R1 and R2 is methyl, ethyl or isopropyl, and the other is H; R3 and R4 are each independently H, branched or unbranched C1-C6 alkyl, or aryl, and wherein at least one of R3 and R4 is other than H; R5 is a branched or unbranched C1-C5 alkyl group or a C1-C6 cycloalkyl group, each of which may be optionally substituted with one or more OH groups; R6, R7, R8 and R9 are each independently H, halogen, NO2, OH, OMe, CN, NH2, COOH, CONH2, or SO2NH2. A further aspect of the invention relates to pharmaceutical compositions comprising compounds of formula 1, and the use of said compounds in treating proliferative disorders, viral disorders, CNS disorders, diabetes, stroke, alopecia or neurodegenerative disorders.

    Abstract translation: 本发明涉及式1化合物或其药学上可接受的盐，其中R 1和R 2之一是甲基，乙基或异丙基，另一个是H; R 3和R 4各自独立地为H，支链或非支链C 1 -C 6烷基或芳基 并且其中R 3和R 4中的至少一个不是H; R 5是支链或非支链C 1 -C 5烷基或C 1 -C 3亚烷基 其中每一个可以任选地被一个或多个OH基团取代; R 6，R 7，R 8和R 9各自独立地为H，卤素，NO 3， 2，OH，OMe，CN，NH 2，COOH，CONH 2或SO 2 NH 2， / SUB>。 本发明的另一方面涉及包含式1化合物的药物组合物，以及所述化合物在治疗增殖性疾病，病毒性疾病，中枢神经系统疾病，糖尿病，中风，脱发或神经变性疾病中的用途。

    Lamp burning vaporizable liquid fuel
    9.
    发明授权
    Lamp burning vaporizable liquid fuel 失效
    灯燃燃烧可燃液体燃料

    公开(公告)号：US4025280A

    公开(公告)日：1977-05-24

    申请号：US460873

    申请日：1974-04-15

    Applicant: Leslie Peter Stuart Wilson

    Inventor： Leslie Peter Stuart Wilson

    IPC: F21L19/00 ,  F21V37/00 ,  F23D5/00 ,  F23C3/02 ,  F23D3/04

    CPC classification number: F21V37/00 ,  F21L19/00 ,  F23D5/00

    Abstract: A lamp burning a vaporizable oil produces both a steady light and a regularly recurring bright flash. The lamp has a non-combustible wick in a cooled metal tubular wick holder, the upper part of the wick holder being surrounded by an open-topped combustion chamber which extends inwardly towards a pilot flame on the wick. Heating of the combustion chamber induces air flow causing an explosive mixture to form in the chamber; this is ignited by the pilot flame to give a bright flash.

    Abstract translation: 燃烧可汽化油的灯产生稳定的光和定期重现的明亮闪光。 该灯在一个冷却的金属管状灯芯支架中具有不可燃的灯芯，灯芯保持架的上部由敞开的燃烧室包围，该敞开的燃烧室向内朝着灯芯上的引燃火焰向内延伸。 燃烧室的加热引起气流，导致在室中形成爆炸性混合物; 这被引燃火焰点燃，发出明亮的闪光。

    INTEGRATED SECURITY NETWORK
    10.
    发明申请
    INTEGRATED SECURITY NETWORK 审中-公开

    公开(公告)号：US20180293859A1

    公开(公告)日：2018-10-11

    申请号：US15984867

    申请日：2018-05-21

    Applicant: David Stuart Wilson ,  Andrew Wilson

    Inventor： David Stuart Wilson ,  Andrew Wilson

    IPC: G08B13/196 ,  G08B25/00 ,  G08B25/14 ,  H04L9/00 ,  H04L9/08 ,  G08B29/04

    CPC classification number: G08B13/19656 ,  G08B13/19665 ,  G08B25/002 ,  G08B25/14 ,  G08B29/046 ,  H04L9/00 ,  H04L9/0819

    Abstract: A security system architecture and method of operation that combines a local security network with control panel and sensors, a central monitoring station (CMS), and a separate operator computer server that provides a web portal for both the homeowner and CMS, that maintains a persistent connection between the control panel and CMS allowing failsafe dual-path signaling. This dual-path signaling technique is extended to provide an effective “smash and grab alarm”, and various approaches to dual-path signal management are disclosed including handshaking, persistent domain monitoring, relayed Operator 3-to-CMS signaling, etc. Improved processes for remotely accessing video are also disclosed along with an improved process for remote control panel configuration, and control panel interfacing with home automation appliances.

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