CELL CULTURE CARRIER, AND METHOD AND DEVICE FOR PRODUCING SAME

    公开(公告)号:US20220002704A1

    公开(公告)日:2022-01-06

    申请号:US17479037

    申请日:2021-09-20

    Abstract: This invention is to develop a production method for a cell culture carrier comprising a hydrogel having high shape retainability, and cell culture carrier production device, and to provide a structure composed of a cell culture carrier produced using the same.
    The production method comprises a retention step of retaining on a support material a first solution containing a multiple branching polymer comprising polyethylene glycol as the backbone, and having at least one functional group which is one of a nucleophilic functional group and an electrophilic functional group at a side chain(s) and/or a terminal(s), and a gel formation step of forming one or more dot-shaped hydrogels in which a second solution containing a multiple branching polymer comprising polyethylene glycol as the backbone, and having at least one functional group which is the other one of a nucleophilic functional group and an electrophilic functional group at a side chain and/or a terminal, is discharged by a droplet discharge device to land in contact with the first solution retained on the support material.

    LIQUID JET HEAD AND METHOD FOR PRODUCING SAME, AND LIQUID JET APPARATUS AND IMAGE FORMING APPARATUS
    3.
    发明申请
    LIQUID JET HEAD AND METHOD FOR PRODUCING SAME, AND LIQUID JET APPARATUS AND IMAGE FORMING APPARATUS 有权
    液体喷头及其制造方法,液体喷射装置和图像形成装置

    公开(公告)号:US20170043580A1

    公开(公告)日:2017-02-16

    申请号:US15305723

    申请日:2015-05-19

    Abstract: Provided is a liquid jet head, including a flow path including a first member, a resin layer, and a second member, wherein the resin layer contains a cured product of a resin composition containing an epoxy compound represented by General Formula (1), a polythiol compound having 2 or more thiol groups in a molecule thereof, and a specific imidazole compound, where in General Formula (1), L is an integer of 0 or greater but less than 3, m is a positive number of 0.1 or greater but less than 50, R1 represents any one of a hydrogen atom, and an alkyl group having 1 to 4 carbon atoms, and R2 represents a substituent represented by a formula below where R3 and R4 each represent any one of hydrogen atom, and a non-substituted or fluorine-substituted methyl group, and n is an integer of 4 to 12.

    Abstract translation: 提供一种液体喷射头,其包括具有第一部件,树脂层和第二部件的流路,其中,所述树脂层含有含有通式(1)表示的环氧化合物的树脂组合物的固化物, 分子中具有2个以上硫醇基的多硫醇化合物和特定的咪唑化合物,通式(1)中,L为0以上且小于3的整数,m为0.1以上的正数,但为0.1以上的正数 小于50,R 1表示氢原子和具有1〜4个碳原子的烷基中的任一个,R 2表示下式所示的取代基,其中,R 3和R 4各自表示氢原子, 取代或氟取代的甲基,n为4〜12的整数。

    LAYERED BODY
    10.
    发明申请

    公开(公告)号:US20210147795A1

    公开(公告)日:2021-05-20

    申请号:US17094935

    申请日:2020-11-11

    Abstract: An object of the present invention is to provide a layered body of cells that is used in a co-culture technique and that is capable of recognizing as paracrine effect of each cell and detecting the effect with high intensity. The layered body of the present invention is a layered body 1A having a layered structure in which a gel layer 20a containing a hydrogel is disposed between at least two cell layers 10a and 10b containing cells of different types from each other, wherein the hydrogel is a multi-branched polymer hydrogel formed by a reaction of: Liquid A containing a multi-branched polymer A, the polymer containing, as a backbone, a polyethylene glycol containing at least three branches, the branches containing one or more electrophilic functional groups in at least one of a side chain(s) and an end(s); and Liquid B containing a multi-branched polymer B, the polymer containing, as a backbone, a polyethylene glycol containing at least three branches, the branches containing one or more nucleophilic functional groups in at least one of a side chain(s) and an end(s), the concentration of components derived from the multi-branched polymers A and B in the hydrogel is from 0.6 to 8% by weight, and the thickness is from 0.02 mm to 2 mm.

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