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    Circulating epstein-barr virus DNA in the serum of patients with gastric carcinoma
    1.
    发明授权
    Circulating epstein-barr virus DNA in the serum of patients with gastric carcinoma 有权
    在胃癌患者血清中循环epstein-barr病毒DNA

    公开(公告)号：US06753137B2

    公开(公告)日：2004-06-22

    申请号：US10057579

    申请日：2002-01-25

    申请人： Yuk Ming Dennis Lo ,  Wing Yee Chan ,  Kwok Wai Ng

    发明人： Yuk Ming Dennis Lo ,  Wing Yee Chan ,  Kwok Wai Ng

    IPC分类号： C12Q170

    CPC分类号： C12Q1/6886 ,  C12Q1/705

    摘要： The present invention features methods for diagnosing, detecting, monitoring and determining the prognosis of gastric cancer, non-head and neck and lymphoid malignancies, and gastritis in a patient by detecting or measuring EBV DNA present in the serum or plasma of the patient. The present invention also features diagnostic kits comprising suitable reagents for detecting EBV DNA in the serum or plasma of a patient.

    摘要翻译： 本发明的特征在于通过检测或测量患者的血清或血浆中存在的EBV DNA来诊断，检测，监测和确定患者的胃癌，非头颈部和淋巴恶性肿瘤以及胃炎的预后的方法。 本发明还具有包含用于检测患者的血清或血浆中的EBV DNA的合适试剂的诊断试剂盒。

    Immunity testing device
    2.
    发明授权
    Immunity testing device 失效
    免疫检测装置

    公开(公告)号：US06326214B1

    公开(公告)日：2001-12-04

    申请号：US09261753

    申请日：1999-03-03

    申请人： Yung Hsiang Liu ,  Wing-yee Chan

    发明人： Yung Hsiang Liu ,  Wing-yee Chan

    IPC分类号： G01N33543

    CPC分类号： G01N33/54366 ,  Y10S435/805 ,  Y10S435/81 ,  Y10S435/969 ,  Y10S435/97 ,  Y10S435/975 ,  Y10S436/81 ,  Y10S436/823

    摘要： An immunity testing device formed of a thin sheet of material folded to three portions, and the two end portions; named “front cover”0 and “back cover”; fold back to different sides of the center part; named base seat; to provide protection on both sides of the base seat. Two absorbent sheets bridged with a test paper are fixed on the side of base seat that's facing the front cover. A hole is present at the position of the first absorbent sheet on base seat for specimen application. The front cover is disposed with observation cover plates at the position corresponding to the test paper and/or water-absorbing sheets for observation of test result as well as for preventing pollution before, and after use. The test paper is pre-embedded with antibodies/antigens to capture the corresponding antigens/antibodies in the test specimen as in Immunity method. The used testing device can be burned down to ensure environmental protection. The first water-absorbent sheet may be extended into part of the unfolding area under the observation cover plate for chemical testing in addition to immunological test method, therefor, dual methods testing is achieved.

    摘要翻译： 一种由折叠成三部分的薄片材料形成的抗扰度测试装置和两个端部; 名为“前盖”0和“后盖”; 折回中心部分的不同侧面; 命名基座; 在基座两侧提供保护。 与测试纸桥接的两个吸收片固定在基座的面向前盖的一侧。 在用于样本施加的基座上的第一吸收性片材的位置处存在孔。 前盖在与试纸和/或吸水片相对应的位置处设有观察盖板，用于观察测试结果以及在使用前和使用后防止污染。 测试纸预先嵌入抗体/抗原，以免疫测试方法捕获测试样品中相应的抗原/抗体。 使用的测试装置可以被烧毁以确保环境保护。 除了免疫学试验方法之外，第一吸水性片材可以延伸到用于化学测试的观察盖板下方的展开区域的一部分中，从而实现双重方法测试。

    Immunological analytical method and device for the determination of advanced glycosylation end products (AGEs)
    4.
    发明申请
    Immunological analytical method and device for the determination of advanced glycosylation end products (AGEs) 审中-公开
    用于测定晚期糖基化终产物（AGEs）的免疫分析方法和装置

    公开(公告)号：US20080160506A1

    公开(公告)日：2008-07-03

    申请号：US12073278

    申请日：2008-03-04

    申请人： Yung-Hsiang Liu ,  Wing-Yee Chan

    发明人： Yung-Hsiang Liu ,  Wing-Yee Chan

    IPC分类号： C12Q1/00

    CPC分类号： G01N33/6842 ,  G01N33/54386 ,  G01N33/558 ,  G01N33/68

    摘要： The invention provides an immunological analytical method and devices for determination of the advanced glycosylation end products (AGEs), comprising a reagents for determining the AGEs, which comprises a displaying carrier suspension and the antigen or antibody immobilized on the surface of the said displaying carrier; and a test strip, comprising of: a base plate, and constitutive parts provided on the said base plate. After infusing the said reagent into the said test strip, the immunological reaction of the AGEs antigen or antibody can be determined based on the agglutination phenomenon or accompanied changes of absorbance or color and the presence or raised level of the AGEs in the diabetic patient can be known accordingly such that the practitioner can prevent the occurrence of the complications, or block further the progression of the complications at the earlier stage.

    摘要翻译： 本发明提供了用于测定晚期糖基化终产物（AGEs）的免疫学分析方法和装置，其包含用于测定AGEs的试剂，其包含显示载体悬浮液和固定在所述显示载体表面上的抗原或抗体; 和测试条，包括：基板和设置在所述基板上的构成部分。 在将所述试剂注入所述测试条中后，可以基于凝集现象或伴随的吸光度或颜色的变化来确定AGEs抗原或抗体的免疫反应，并且糖尿病患者中AGEs的存在或升高的水平可以是 因此，医师可以防止并发症的发生，或者进一步阻止早期阶段的并发症的进展。

    ADHESIVE BANDAGE
    5.
    发明申请
    ADHESIVE BANDAGE 审中-公开

    公开(公告)号：US20120220975A1

    公开(公告)日：2012-08-30

    申请号：US13347727

    申请日：2012-01-11

    申请人： Jennifer Wing-Yee Chan ,  Michael W. Eknoian ,  Megha Reddy ,  Carmine Michael Rizzo ,  Vincent John Petersack

    发明人： Jennifer Wing-Yee Chan ,  Michael W. Eknoian ,  Megha Reddy ,  Carmine Michael Rizzo ,  Vincent John Petersack

    IPC分类号： A61F13/56

    CPC分类号： A61F13/0223 ,  A61F13/0206

    摘要： Adhesive bandages having a backing layer with first and second opposing surfaces, an adhesive layer applied to the second surface of the backing layer and an absorbent pad associated with the backing layer, the absorbent pad including a first surface that faces the second surface of the backing layer and an opposing second surface having a plurality of tufted regions surrounded and separated by a first network of interconnecting channels recessed in the second surface of the absorbent pad; where the shape of the tufted regions is a polygon having from five to eight sides, the tufted regions have a substantially uniform first density, the channel base region has a substantially uniform second density that is greater than the substantially uniform first density of the tufted regions and the network of channels is visible.

    ADHESIVE BANDAGE
    6.
    发明申请
    ADHESIVE BANDAGE 审中-公开
    粘合剂

    公开(公告)号：US20120220974A1

    公开(公告)日：2012-08-30

    申请号：US13036499

    申请日：2011-02-28

    申请人： Jennifer Wing-Yee Chan ,  Michael W. Eknoian ,  Megha Reddy ,  Carmine Michael Rizzo ,  Vincent John Petersack

    发明人： Jennifer Wing-Yee Chan ,  Michael W. Eknoian ,  Megha Reddy ,  Carmine Michael Rizzo ,  Vincent John Petersack

    IPC分类号： A61F13/53

    CPC分类号： A61F13/0223 ,  A61F13/0206

    摘要： Adhesive bandages having a backing layer with first and second opposing surfaces, an adhesive layer applied to the second surface of the backing layer and an absorbent pad associated with the backing layer, the absorbent pad including a first surface that faces the second surface of the backing layer and an opposing second surface having a plurality of tufted regions surrounded and separated by a first network of interconnecting channels recessed in the second surface of the absorbent pad; where the shape of the tufted regions is a polygon having from five to eight sides, the tufted regions have a substantially uniform first density, the channel base region has a substantially uniform second density that is greater than the substantially uniform first density of the tufted regions and the network of channels is visible.

    摘要翻译： 具有带有第一和第二相对表面的背衬层的粘合绷带，施加到背衬层的第二表面的粘合剂层和与背衬层相关联的吸收垫，吸收垫包括面向背衬的第二表面的第一表面 层和相对的第二表面，其具有由在吸收垫的第二表面中凹陷的互连通道的第一网络包围和分隔的多个簇状区域; 簇簇区域的形状是具有五至八边的多边形，簇簇区域具有基本上均匀的第一密度，沟道基区具有基本上均匀的第二密度，该密度大于簇状区域的基本上均匀的第一密度 并且通道网络是可见的。

    ADHESIVE BANDAGE
    9.
    发明申请
    ADHESIVE BANDAGE 审中-公开
    粘合剂

    公开(公告)号：US20120220973A1

    公开(公告)日：2012-08-30

    申请号：US13036471

    申请日：2011-02-28

    申请人： Jennifer Wing-Yee Chan ,  Michael W. Eknoian ,  Megha Reddy ,  Carmine Michael Rizzo ,  Vincent John Petersack

    发明人： Jennifer Wing-Yee Chan ,  Michael W. Eknoian ,  Megha Reddy ,  Carmine Michael Rizzo ,  Vincent John Petersack

    IPC分类号： A61F13/53

    CPC分类号： A61F13/0223 ,  A61F13/0206

    摘要： Adhesive bandages having a backing layer with first and second opposing surfaces, and an absorbent pad associated with the backing layer, the absorbent pad including a first surface that faces the second surface of the backing layer and an opposing second surface having a plurality of tufted regions surrounded and separated by a first network of interconnecting channels recessed in the second surface of the absorbent pad; where the tufted regions have a substantially uniform first density, the channel base region has a substantially uniform second density that is greater than the substantially uniform first density of the tufted regions and the network of channels is visible.

    摘要翻译： 具有背衬层的粘合绷带具有第一和第二相对表面，以及与背衬层相关联的吸收垫，吸收垫包括面向背衬层的第二表面的第一表面和具有多个簇状区域的相对的第二表面 由在吸收垫的第二表面中凹陷的互连通道的第一网络包围和分隔; 其中簇簇区域具有基本上均匀的第一密度，所述沟道基区具有大于簇簇区域的基本均匀的第一密度的大致均匀的第二密度，并且通道网络是可见的。

    Immunological analytical reagent for the determination of advance glycosylation end products (AGEs)
    10.
    发明申请
    Immunological analytical reagent for the determination of advance glycosylation end products (AGEs) 审中-公开
    用于测定先进糖基化终产物（AGEs）的免疫分析试剂

    公开(公告)号：US20090017470A1

    公开(公告)日：2009-01-15

    申请号：US12068683

    申请日：2008-02-11

    申请人： Yung-Hsiang Liu ,  Wing-Yee Chan

    发明人： Yung-Hsiang Liu ,  Wing-Yee Chan

    IPC分类号： G01N33/53

    CPC分类号： G01N33/6842 ,  G01N33/54386 ,  G01N33/558 ,  G01N33/68

    摘要： The invention provides a reagent for determination of Advance Glycosylation End Products (AGEs), comprising a suspension disposed with displaying carrier and the antigen or antibody immobilized on the surface of the said displaying carrier; and a test strip, comprising of: a base plate, and constitutive parts provided on said base plate, said constitutive parts consisting of a water absorption pad for the sample, a porous fiber membrane, a displaying carrier fiber block and at least one immobilized substance. After infusing the said reagent into the said test strip, the immunological reaction of the AGEs antigen or antibody can be determined based on the agglutination phenomenon or accompanied changes of absorbance or color and the presence or raised level of the AGEs in the diabetic patient can be known accordingly such that the practitioner can prevent the occurrence of the complicated condition, or block further the progression of the complications at the earlier stage.

    摘要翻译： 本发明提供了一种用于测定高级糖基化终产物（AGE）的试剂，其包含悬置于显示载体上的悬浮液，并且所述抗原或抗体固定在所述显示载体的表面上; 和测试条，包括：基板和设置在所述基板上的构成部分，所述构成部分由用于样品的吸水垫，多孔纤维膜，显示载体纤维块和至少一种固定化物质 。 在将所述试剂注入所述测试条中后，可以基于凝集现象或伴随的吸光度或颜色的变化来确定AGEs抗原或抗体的免疫反应，并且糖尿病患者中AGEs的存在或升高的水平可以是 因此，医生可以防止复杂状况的发生，或者进一步阻止早期并发症的发展。