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公开(公告)号：US20080076167A1
公开(公告)日：2008-03-27
申请号：US11942669
申请日：2007-11-19
申请人： Ravi GOKARN , Olga SELIFONOVA , Holly JESSEN , Steven GORT , Thorsten SELMER , Wolfgang BUCKEL
发明人： Ravi GOKARN , Olga SELIFONOVA , Holly JESSEN , Steven GORT , Thorsten SELMER , Wolfgang BUCKEL
摘要： Methods and materials related to producing 3-HP as well as other organic compounds are disclosed. Specifically, isolated nucleic acids, polypeptides, host cells, and methods and materials for producing 3-HP and other organic compounds are disclosed.
摘要翻译： 公开了与生产3-HP以及其它有机化合物相关的方法和材料。 具体地，公开了分离的核酸，多肽，宿主细胞以及用于产生3-HP和其它有机化合物的方法和材料。
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公开(公告)号：US08501455B2
公开(公告)日：2013-08-06
申请号：US13467165
申请日：2012-05-09
申请人： Ravi R. Gokarn , Olga V. Selifonova , Holly Jean Jessen , Steven John Gort , Thorsten Selmer , Wolfgang Buckel
发明人： Ravi R. Gokarn , Olga V. Selifonova , Holly Jean Jessen , Steven John Gort , Thorsten Selmer , Wolfgang Buckel
摘要： Methods and materials related to producing 3-HP as well as other organic compounds are disclosed. Specifically, isolated nucleic acids, polypeptides, host cells, and methods and materials for producing 3-HP and other organic compounds are disclosed.
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公开(公告)号：US08076120B2
公开(公告)日：2011-12-13
申请号：US12127700
申请日：2008-05-27
申请人： Ravi R. Gokarn , Olga V. Selifonova , Holly Jean Jessen , Steven John Gort , Thorsten Selmer , Wolfgang Buckel
发明人： Ravi R. Gokarn , Olga V. Selifonova , Holly Jean Jessen , Steven John Gort , Thorsten Selmer , Wolfgang Buckel
IPC分类号： C12N1/20
摘要： Methods and materials related to producing 3-HP as well as other organic compounds are disclosed. Specifically, isolated nucleic acids, polypeptides, host cells, and methods and materials for producing 3-HP and other organic compounds are disclosed.
摘要翻译： 公开了与生产3-HP以及其它有机化合物相关的方法和材料。 具体地，公开了分离的核酸，多肽，宿主细胞以及用于产生3-HP和其它有机化合物的方法和材料。
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公开(公告)号：US20090053783A1
公开(公告)日：2009-02-26
申请号：US12127700
申请日：2008-05-27
申请人： Ravi R. Gokarn , Olga V. Selifonova , Holly Jean Jessen , Steven John Gort , Thorsten Selmer , Wolfgang Buckel
发明人： Ravi R. Gokarn , Olga V. Selifonova , Holly Jean Jessen , Steven John Gort , Thorsten Selmer , Wolfgang Buckel
摘要： Methods and materials related to producing 3-HP as well as other organic compounds are disclosed. Specifically, isolated nucleic acids, polypeptides, host cells, and methods and materials for producing 3-HP and other organic compounds are disclosed.
摘要翻译： 公开了与生产3-HP以及其它有机化合物相关的方法和材料。 具体地，公开了分离的核酸，多肽，宿主细胞以及用于产生3-HP和其它有机化合物的方法和材料。
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公开(公告)号：US07186541B2
公开(公告)日：2007-03-06
申请号：US10432443
申请日：2001-11-20
申请人： Ravi R. Gokarn , Olga V. Selifonova , Holly Jean Jessen , Steven John Gort , Thorsten Selmer , Wolfgang Buckel
发明人： Ravi R. Gokarn , Olga V. Selifonova , Holly Jean Jessen , Steven John Gort , Thorsten Selmer , Wolfgang Buckel
摘要： Methods and materials related to producing 3-HP as well as other organic compounds are disclosed. Specifically, isolated nucleic acids, polypeptides, host cells, and methods and materials for producing 3-HP and other organic compounds are disclosed.
摘要翻译： 公开了与生产3-HP以及其它有机化合物相关的方法和材料。 具体地，公开了分离的核酸，多肽，宿主细胞以及用于产生3-HP和其它有机化合物的方法和材料。
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公开(公告)号：US07638316B2
公开(公告)日：2009-12-29
申请号：US11942669
申请日：2007-11-19
申请人： Ravi R. Gokarn , Olga V. Selifonova , Holly Jean Jessen , Steven John Gort , Thorsten Selmer , Wolfgang Buckel
发明人： Ravi R. Gokarn , Olga V. Selifonova , Holly Jean Jessen , Steven John Gort , Thorsten Selmer , Wolfgang Buckel
IPC分类号： C12P7/62
摘要： Methods and materials related to producing 3-HP as well as other organic compounds are disclosed. Specifically, isolated nucleic acids, polypeptides, host cells, and methods and materials for producing 3-HP and other organic compounds are disclosed.
摘要翻译： 公开了与生产3-HP以及其它有机化合物相关的方法和材料。 具体地，公开了分离的核酸，多肽，宿主细胞以及用于产生3-HP和其它有机化合物的方法和材料。
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公开(公告)号：US08778645B2
公开(公告)日：2014-07-15
申请号：US13144616
申请日：2010-01-15
申请人： Oskar Zelder , Wolfgang Buckel , Ivana Djurdjevic
发明人： Oskar Zelder , Wolfgang Buckel , Ivana Djurdjevic
CPC分类号： C12P7/44 , C12N9/0006 , C12N9/13 , C12N9/88 , C12P7/50
摘要： The present invention relates to a novel method for the biocatalytic production of unsaturated dicarboxylic acids by cultivating a recombinant microorganism co-expressing a glutaconate CoA-transferase and a 2-hydroxyglutaryl-CoA dehydratase system. The present invention also relates to corresponding recombinant hosts, recombinant vectors, expression cassettes and nucleic acids suitable for preparing such hosts as well as a method of preparing polyamide or polyester copolymers making use of said dicarboxylic acids as obtained by said biocatalytic production method.
摘要翻译： 本发明涉及通过培养共表达戊二酸CoA转移酶和2-羟基戊二酰辅酶A脱水酶系统的重组微生物来生物催化生产不饱和二羧酸的新方法。 本发明还涉及适用于制备这种宿主的相应的重组宿主，重组载体，表达盒和核酸以及通过所述生物催化生产方法获得的制备使用所述二羧酸的聚酰胺或聚酯共聚物的方法。
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公开(公告)号：US20120244586A1
公开(公告)日：2012-09-27
申请号：US13467165
申请日：2012-05-09
申请人： Ravi R. Gokarn , Olga V. Selifonova , Holly Jean Jessen , Steven John Gort , Thorsten Selmer , Wolfgang Buckel
发明人： Ravi R. Gokarn , Olga V. Selifonova , Holly Jean Jessen , Steven John Gort , Thorsten Selmer , Wolfgang Buckel
摘要： Methods and materials related to producing 3-HP as well as other organic compounds are disclosed. Specifically, isolated nucleic acids, polypeptides, host cells, and methods and materials for producing 3-HP and other organic compounds are disclosed.
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公开(公告)号：US08198066B2
公开(公告)日：2012-06-12
申请号：US13294820
申请日：2011-11-11
申请人： Ravi R. Gokarn , Olga V. Selifonova , Holly Jean Jessen , Steven John Gort , Thorsten Selmer , Wolfgang Buckel
发明人： Ravi R. Gokarn , Olga V. Selifonova , Holly Jean Jessen , Steven John Gort , Thorsten Selmer , Wolfgang Buckel
IPC分类号： C12N1/20
摘要： Methods and materials related to producing 3-HP as well as other organic compounds are disclosed. Specifically, isolated nucleic acids, polypeptides, host cells, and methods and materials for producing 3-HP and other organic compounds are disclosed.
摘要翻译： 公开了与生产3-HP以及其它有机化合物相关的方法和材料。 具体地，公开了分离的核酸，多肽，宿主细胞以及用于产生3-HP和其它有机化合物的方法和材料。
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公开(公告)号：US20120021472A1
公开(公告)日：2012-01-26
申请号：US13144616
申请日：2010-01-15
申请人： Oskar Zelder , Wolfgang Buckel , Ivana Djurdjevic
发明人： Oskar Zelder , Wolfgang Buckel , Ivana Djurdjevic
CPC分类号： C12P7/44 , C12N9/0006 , C12N9/13 , C12N9/88 , C12P7/50
摘要： The present invention relates to a novel method for the biocatalytic production of unsaturated dicarboxylic acids by cultivating a recombinant microorganism co-expressing a glutaconate CoA-transferase and a 2-hydroxyglutaryl-CoA dehydratase system. The present invention also relates to corresponding recombinant hosts, recombinant vectors, expression cassettes and nucleic acids suitable for preparing such hosts as well as a method of preparing polyamide or polyester copolymers making use of said dicarboxylic acids as obtained by said biocatalytic production method.
摘要翻译： 本发明涉及通过培养共表达戊二酸CoA转移酶和2-羟基戊二酰辅酶A脱水酶系统的重组微生物来生物催化生产不饱和二羧酸的新方法。 本发明还涉及适用于制备这种宿主的相应的重组宿主，重组载体，表达盒和核酸以及通过所述生物催化生产方法获得的制备使用所述二羧酸的聚酰胺或聚酯共聚物的方法。
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