公开(公告)号：US20230190988A1

公开(公告)日：2023-06-22

申请号：US17925558

申请日：2021-06-03

Applicant: 3M INNOVATIVE PROPERTIES COMPANY

Inventor： Petra L. Kohler Riedi ,  Saurabh Batra ,  Naimul Karim ,  Joseph J. Stoffel ,  Rajan B. Bodkhe ,  Joseph A. Dunbar

IPC: A61L15/42 ,  A61L15/24 ,  A61L15/46 ,  A61L15/62

CPC classification number: A61L15/425 ,  A61L15/24 ,  A61L15/46 ,  A61L15/62

Abstract: A wound dressing material comprises a porous flexible foam core, a wound-contact scrim, and an antimicrobial layer. The wound-contact scrim comprises water-sensitive fibers comprising a copolymer comprising divalent hydroxyethylene monomer units and divalent dihydroxybutylene monomer units. The antimicrobial layer is sandwiched between the porous flexible foam core and the wound-contact scrim. The wounds dressing material may be contacted with an exposed surface of a wound. A method of making the wound dressing material is also disclosed.

公开(公告)号：US20230372578A1

公开(公告)日：2023-11-23

申请号：US18044692

申请日：2021-08-10

Applicant: 3M INNOVATIVE PROPERTIES COMPANY

Inventor： Petra L. Kohler Riedi ,  Saurabh Batra ,  Rajan B. Bodkhe ,  Joseph J. Stoffel ,  Naimul Karim

IPC: A61L26/00 ,  A61F13/02 ,  A61F13/00

CPC classification number: A61L26/0052 ,  A61L26/0066 ,  A61L26/0085 ,  A61F13/0206 ,  A61F13/00063 ,  A61L2300/404 ,  A61L2300/21

Abstract: A wound dressing material comprises: a first water-sensitive film comprising a first copolymer comprising first divalent hydroxyethylene monomer units and first divalent dihydroxybutylene monomer units; and a first antimicrobial layer disposed on the first water-sensitive film. Methods of making and using the wound dressing material are also disclosed.

公开(公告)号：US20220228306A1

公开(公告)日：2022-07-21

申请号：US17595549

申请日：2020-06-12

Applicant: 3M INNOVATIVE PROPERTIES COMPANY

Inventor： Petra L. Kohler Reidi ,  Saurabh Batra ,  Hannah C. Cohen ,  Semra Colak Atan ,  Naimul Karim ,  Joseph J. Stoffel ,  Joseph A. Dunbar ,  Colby W. Dotseth

IPC: D04H1/56 ,  D04H1/4291 ,  D04H1/4309 ,  D04H1/4258 ,  D01F6/34 ,  D01F8/10

Abstract: A method of making a nonwoven fiber web comprises: providing a melt-blown nonwoven fiber web comprising bonded primary fibers having an average fiber diameter of 2 to 100 microns, wherein the primary fibers comprise a copolymer comprising divalent hydroxyethylene monomer units and divalent dihydroxybutylene monomer units; opening at least a portion of the melt-blown nonwoven fiber web to provide loose primary fibers; combining the loose primary fibers with secondary fibers; and forming a secondary nonwoven fiber web comprising the primary fibers and secondary fibers. A fiber web preparable according to the method and a multicomponent fiber including a first phase comprising a copolymer comprising divalent hydroxyethylene monomer units and divalent dihydroxybutylene monomer units and a second phase comprising a non-biodegradable polymer.

公开(公告)号：US20150072966A1

公开(公告)日：2015-03-12

申请号：US14381636

申请日：2013-02-28

Applicant: 3M INNOVATIVE PROPERTIES COMPANY

Inventor： Joseph V. Boykin, JR. ,  Stephanie F. Bernatchez ,  Vinod P. Menon ,  Joseph J. Stoffel ,  Joseph A. Tucker

IPC: G01N33/84 ,  A61K31/198 ,  A61K31/573

CPC classification number: G01N33/84 ,  A61K31/198 ,  A61K31/573 ,  G01N33/523 ,  G01N2800/20 ,  Y10T436/173076

Abstract: A method of establishing a therapeutic window of wound fluid nitric oxide (WFNO) in the wound of a mammal, the method including: obtaining a wound fluid sample from a mammal; analyzing the WFNO level; determining whether the WFNO is at or below a lower threshold level, or is at or above an upper threshold level; wherein the lower threshold level and upper threshold level define the therapeutic window of WFNO; and treating the mammal with a substance that alters the WFNO level such that the therapeutic window of WFNO in the wound is established.

Abstract translation: 一种在哺乳动物的伤口中建立伤口液一氧化氮（WFNO）的治疗窗口的方法，所述方法包括：从哺乳动物获得伤口液样品; 分析WFNO水平; 确定WFNO是否处于或低于较低阈值水平，或处于或高于上阈值水平; 其中下阈值水平和上阈值水平定义了WFNO的治疗窗口; 并用改变WFNO水平的物质治疗哺乳动物，使得创伤中的WFNO的治疗窗口成立。

公开(公告)号：US20220378621A1

公开(公告)日：2022-12-01

申请号：US17770938

申请日：2020-10-12

Applicant: 3M INNOVATIVE PROPERTIES COMPANY

Inventor： Petra L. Kohler Riedi ,  Saurabh Batra ,  Naimul Karim ,  Joseph J. Stoffel ,  Rajan B. Bodkhe ,  Joseph A. Dunbar ,  Colby W. Dotseth

IPC: A61F13/00 ,  D04H1/4309 ,  D04H1/732

Abstract: A wound dressing material comprises first and second wound-contact scrims, and an antimicrobial layer disposed therebetween. The wound-contact scrims comprise water-sensitive fibers comprising a copolymer comprising divalent hydroxyethylene monomer units and divalent dihydroxybutylene monomer units. The wound dressing material may be contacted with an exposed surface of a wound. A method of making the wound dressing material is also disclosed.

公开(公告)号：US20220280681A1

公开(公告)日：2022-09-08

申请号：US17637784

申请日：2020-09-24

Applicant: 3M INNOVATIVE PROPERTIES COMPANY

Inventor： Petra L. Kohler Riedi ,  Saurabh Batra ,  Naimul Karim ,  Joseph J. Stoffel ,  Rajan B. Bodkhe ,  Joseph A. Dunbar ,  Colby W. Dotseth ,  Semra Colak Atan

IPC: A61L15/44 ,  A61L15/22

Abstract: A wound dressing material comprises a base fiber web, a wound-contact scrim, and an antimicrobial layer. The wound-contact scrim comprises water-sensitive fibers comprising a copolymer comprising divalent hydroxyethylene monomer units and divalent dihydroxybutylene monomer units. The antimicrobial layer is sandwiched between the base fiber web and the wound-contact scrim. The wounds dressing material may be contacted with an exposed surface of a wound. A method of making the wound dressing material is also disclosed.