公开(公告)号：US20200330347A1

公开(公告)日：2020-10-22

申请号：US16955224

申请日：2018-12-18

Applicant: 3M INNOVATIVE PROPERTIES COMPANY

Inventor： Katie F. Wlaschin ,  Amanda C. Engler ,  Hannah C. Cohen ,  Yizhong Wang ,  Tao Gong ,  Tiffany T. Ton ,  Joel D. Oxman ,  Jie Yang

IPC: A61K8/36 ,  A61K8/92 ,  A61K8/73 ,  A61K8/9794 ,  A61K8/42 ,  A61K8/67 ,  A61K8/49 ,  A61K8/365 ,  A61Q11/00

Abstract: Compositions that include: from 5 wt-% to 70 wt-% of one or more plant based oils based on the total weight of the composition; from 35 wt-% to 95 wt-% of an aqueous phase based on the total weight of the composition; not greater than 7.5 wt-% of one or more surfactants based on the total weight of the composition; and not greater than 3 wt-% of a viscosity modifier of, wherein the composition has a pH from 4.5 to 9.5, the composition is an oil in water (o/w) emulsion, and the composition is edible. Methods of utilizing disclosed compositions are also included.

公开(公告)号：US20190099338A1

公开(公告)日：2019-04-04

申请号：US16148415

申请日：2018-10-01

Applicant: 3M INNOVATIVE PROPERTIES COMPANY

Inventor： Yizhong Wang ,  Tiffany T. Ton ,  Melinda B. Gustafson ,  Jennifer Post ,  Paul R. Klaiber ,  Carola A. Carrera Vidal ,  Joel D. Oxman

IPC: A61K8/21 ,  A61Q11/00 ,  A61K8/81 ,  A61K8/26 ,  A61K8/19 ,  A61K8/24 ,  A61C19/06

Abstract: An aqueous oral care fluoride treatment composition, a method of providing fluoride to a patient's tooth surface, and a method of reducing the incidence of dental caries, wherein the composition includes: 0.1 wt-% to 3.0 wt-% of a crosslinked poly acid having carboxylic acid side groups; a pharmaceutically acceptable buffer; 1.0 wt-% to 2.5 wt-% of sodium fluoride; 0.025 wt-% to 1.75 wt-% of a multivalent cation salt; and at least 60 wt-% water; wherein the weight percentages are based on the total weight of the aqueous composition.

公开(公告)号：US20200268625A1

公开(公告)日：2020-08-27

申请号：US16871422

申请日：2020-05-11

Applicant: 3M INNOVATIVE PROPERTIES COMPANY

Inventor： Yizhong Wang ,  Tiffany T. Ton ,  Melinda B. Gustafson ,  Jennifer Post ,  Paul R. Klaiber ,  Carola A. Carrera Vidal ,  Joel D. Oxman

IPC: A61K8/21 ,  A61K45/06 ,  A61K33/16 ,  A61K8/73 ,  A61K8/27 ,  A61C19/06 ,  A61K8/19 ,  A61K8/24 ,  A61K8/26 ,  A61K8/81 ,  A61Q11/00

Abstract: An aqueous oral care fluoride treatment composition, a method of providing fluoride to a patient's tooth surface, and a method of reducing the incidence of dental caries, wherein the composition includes: 0.1 wt-% to 3.0 wt-% of a crosslinked poly acid having carboxylic acid side groups; a pharmaceutically acceptable buffer; 1.0 wt-% to 2.5 wt-% of sodium fluoride; 0.025 wt-% to 1.75 wt-% of a multivalent cation salt; and at least 60 wt-% water; wherein the weight percentages are based on the total weight of the aqueous composition.

公开(公告)号：US20160220473A1

公开(公告)日：2016-08-04

申请号：US14917431

申请日：2014-09-10

Applicant: 3M INNOVATIVE PROPERTIES COMPANY

Inventor： Yizhong Wang ,  Joel D. Oxman ,  Paul R. Klaiber ,  Jie J. Liu ,  Joanne A. Fitch ,  Tiffany T. Ton ,  Reinhold Hecht

IPC: A61K8/81 ,  A61Q11/00

CPC classification number: A61K8/8147 ,  A61K8/8152 ,  A61K2800/5424 ,  A61K2800/594 ,  A61K2800/92 ,  A61Q11/00

Abstract: An oral composition and a method of delivering an oral composition to a dental structure are described. The oral composition can include a solvent; an acidic copolymer having acidic acrylate monomeric units, acidic methacrylate monomeric units, or a combination thereof; a neutral copolymer having neutral acrylate monomeric units, neutral methacrylate monomeric units, or a combination thereof; and optionally an active agent. The acidic and neutral copolymers can be dissolved in the oral composition and the oral composition can form a film on a surface when contacted with an aqueous solution.

Abstract translation: 描述口腔组合物和将口腔组合物递送到牙科结构的方法。 口服组合物可包括溶剂; 具有酸性丙烯酸酯单体单元，酸式甲基丙烯酸酯单体单元或其组合的酸性共聚物; 具有中性丙烯酸酯单体单元，中性甲基丙烯酸酯单体单元或其组合的中性共聚物; 和任选的活性剂。 酸性和中性共聚物可以溶解在口腔组合物中，口服组合物可以在与水溶液接触时在表面上形成膜。

公开(公告)号：US11779446B2

公开(公告)日：2023-10-10

申请号：US16196872

申请日：2018-11-20

Applicant: 3M INNOVATIVE PROPERTIES COMPANY

Inventor： Katie F. Wlaschin ,  Amanda C. Engler ,  Hannah C. Cohen ,  Yizhong Wang ,  Tao Gong ,  Tiffany T. Ton ,  Joel D. Oxman ,  Jie Yang ,  Richard P. Rusin

IPC: A61C19/06 ,  A61P1/02 ,  A61K36/00 ,  A61Q11/00 ,  A61K9/12 ,  A61K8/25 ,  A61K8/41 ,  A61K8/73 ,  A61K8/92 ,  A61K47/12 ,  A61K9/107 ,  A61K47/26 ,  A61K8/81 ,  A61K8/06 ,  A61K9/00 ,  A61K47/10 ,  A61K8/37 ,  A61K36/185 ,  A61K47/36 ,  A61K47/44 ,  A61K36/28 ,  A61K36/63 ,  A61K31/025 ,  A61K31/075 ,  A61K31/164 ,  A61K31/198 ,  A61K31/205 ,  A61K31/355 ,  A61K31/714 ,  A61K31/728 ,  A61K36/48 ,  A61K36/52 ,  A61K36/736 ,  A61K36/752 ,  A61K36/81

CPC classification number: A61C19/063 ,  A61K8/062 ,  A61K8/25 ,  A61K8/375 ,  A61K8/41 ,  A61K8/73 ,  A61K8/731 ,  A61K8/732 ,  A61K8/737 ,  A61K8/8147 ,  A61K8/8176 ,  A61K8/922 ,  A61K9/006 ,  A61K9/0053 ,  A61K9/107 ,  A61K9/12 ,  A61K31/025 ,  A61K31/075 ,  A61K31/164 ,  A61K31/198 ,  A61K31/205 ,  A61K31/355 ,  A61K31/714 ,  A61K31/728 ,  A61K36/00 ,  A61K36/185 ,  A61K36/28 ,  A61K36/48 ,  A61K36/52 ,  A61K36/63 ,  A61K36/736 ,  A61K36/752 ,  A61K36/81 ,  A61K47/10 ,  A61K47/12 ,  A61K47/26 ,  A61K47/36 ,  A61K47/44 ,  A61P1/02 ,  A61Q11/00

Abstract: Compositions that include: from 5 wt-% to 30 wt-% of one or more plant based oils based on the total weight of the composition; from 70 wt-% to 95 wt-% of an aqueous phase based on the total weight of the composition; from 0.1 wt-% to 5 wt-% of one or more surfactants based on the total weight of the composition; and from 0.05 wt-% to 3 wt-% of a viscosity modifier, wherein the composition has a pH from 4.5 to 9.5, the composition is an oil in water (o/w) emulsion, and the composition is edible. Methods of utilizing disclosed compositions are also included.

公开(公告)号：US20220249340A1

公开(公告)日：2022-08-11

申请号：US17724019

申请日：2022-04-19

Applicant: 3M INNOVATIVE PROPERTIES COMPANY

Inventor： Katie F. WLASCHIN ,  Amanda C. Engler ,  Hannah C. Cohen ,  Yizhong Wang ,  Tao Gong ,  Tiffany T. Ton ,  Joel D. OXMAN ,  Jie Yang

IPC: A61K8/36 ,  A61K8/9794 ,  A61K8/365 ,  A61K8/42 ,  A61K8/49 ,  A61K8/67 ,  A61K8/73 ,  A61K8/92 ,  A61Q11/00

Abstract: Compositions that include: from 5 wt-% to 70 wt-% of one or more plant based oils based on the total weight of the composition; from 35 wt-% to 95 wt-% of an aqueous phase based on the total weight of the composition; not greater than 7.5 wt-% of one or more surfactants based on the total weight of the composition; and not greater than 3 wt-% of a viscosity modifier of, wherein the composition has a pH from 4.5 to 9.5, the composition is an oil in water (o/w) emulsion, and the composition is edible. Methods of utilizing disclosed compositions are also included.

公开(公告)号：US11337902B2

公开(公告)日：2022-05-24

申请号：US16871422

申请日：2020-05-11

Applicant: 3M INNOVATIVE PROPERTIES COMPANY

Inventor： Yizhong Wang ,  Tiffany T. Ton ,  Melinda B. Gustafson ,  Jennifer Post ,  Paul R. Klaiber ,  Carola A. Carrera Vidal ,  Joel D. Oxman

IPC: A61K8/21 ,  A61K45/06 ,  A61K33/16 ,  A61K8/73 ,  A61K8/27 ,  A61C19/06 ,  A61K8/19 ,  A61K8/24 ,  A61K8/26 ,  A61K8/81 ,  A61Q11/00

Abstract: An aqueous oral care fluoride treatment composition, a method of providing fluoride to a patient's tooth surface, and a method of reducing the incidence of dental caries, wherein the composition includes: 0.1 wt-% to 3.0 wt-% of a crosslinked poly acid having carboxylic acid side groups; a pharmaceutically acceptable buffer; 1.0 wt-% to 2.5 wt-% of sodium fluoride; 0.025 wt-% to 1.75 wt-% of a multivalent cation salt; and at least 60 wt-% water; wherein the weight percentages are based on the total weight of the aqueous composition.

公开(公告)号：US11324681B2

公开(公告)日：2022-05-10

申请号：US16955224

申请日：2018-12-18

Applicant: 3M INNOVATIVE PROPERTIES COMPANY

Inventor： Katie F. Wlaschin ,  Amanda C. Engler ,  Hannah C. Cohen ,  Yizhong Wang ,  Tao Gong ,  Tiffany T. Ton ,  Joel D. Oxman ,  Jie Yang

IPC: A61K8/36 ,  A61K8/9794 ,  A61K8/365 ,  A61K8/42 ,  A61K8/49 ,  A61K8/67 ,  A61K8/73 ,  A61K8/92 ,  A61Q11/00

Abstract: Compositions that include: from 5 wt-% to 70 wt-% of one or more plant based oils based on the total weight of the composition; from 35 wt-% to 95 wt-% of an aqueous phase based on the total weight of the composition; not greater than 7.5 wt-% of one or more surfactants based on the total weight of the composition; and not greater than 3 wt-% of a viscosity modifier of, wherein the composition has a pH from 4.5 to 9.5, the composition is an oil in water (o/w) emulsion, and the composition is edible. Methods of utilizing disclosed compositions are also included.

公开(公告)号：US11801231B2

公开(公告)日：2023-10-31

申请号：US16226122

申请日：2018-12-19

Applicant: 3M INNOVATIVE PROPERTIES COMPANY

Inventor： Katie F. Wlaschin ,  Amanda C. Engler ,  Hannah C. Cohen ,  Yizhong Wang ,  Tao Gong ,  Tiffany T. Ton ,  Joel D. Oxman ,  Jie Yang

IPC: A61K31/164 ,  A61K9/00 ,  A61K9/107 ,  A61K47/02 ,  A61K47/10 ,  A61P1/02 ,  A61K47/26 ,  A61K47/44

CPC classification number: A61K31/164 ,  A61K9/0053 ,  A61K9/107 ,  A61K47/02 ,  A61K47/10 ,  A61K47/26 ,  A61K47/44 ,  A61P1/02

Abstract: Compositions that include from 0.1 wt-% to 8 wt-% of one or more compounds of formula (I) based on the total weight of the composition

HOCH2—(CHOH)n—CH2NR1R2  (I)

wherein R1 and R2 are independently selected from the group consisting of a hydrogen atom, an alkyl group, C(O)R3, and SO2R4; with R3 and R4 being independently selected from the group consisting of an alkyl group, an aryl group, and an aralkyl group; wherein n is an integer from about 2 to about 5; from 5 wt-% to 95 wt-% of one or more plant based oils based on the total weight of the composition; from 5 wt-% to 80 wt-% water based on the total weight of the composition and from 0.01 wt-% to 1 wt-% of one or more nonionic aromatic phenolic preservatives based on the total weight of the composition wherein the composition has a pH from 4.5 to 9.5, the composition is an emulsion, and the composition is edible.

公开(公告)号：US11666523B2

公开(公告)日：2023-06-06

申请号：US16644415

申请日：2018-08-22

Applicant: 3M INNOVATIVE PROPERTIES COMPANY

Inventor： Yizhong Wang ,  Tiffany T. Ton ,  Carola A. Carrera Vidal ,  Joel D. Oxman ,  Jennifer J. Post ,  Paul R. Klaiber

IPC: A61K8/81 ,  A61K8/21 ,  A61K8/73 ,  A61Q11/00

CPC classification number: A61K8/8147 ,  A61K8/21 ,  A61K8/73 ,  A61Q11/00 ,  A61K2800/5426 ,  A61K2800/56

Abstract: An aqueous oral care fluoride treatment composition, a method of providing fluoride to a patients tooth surface, and a method of reducing the incidence of dental caries, wherein the composition includes: 0.5 wt-% to 4.8 wt-% of a water-soluble cationic N-containing polymer; a pharmaceutically acceptable buffer; 1.0 wt-% to 2.5 wt-% of sodium fluoride; and at least 60 wt-% water; wherein the weight percentages are based on the total weight of the aqueous composition.