公开(公告)号：US11793734B2

公开(公告)日：2023-10-24

申请号：US17158326

申请日：2021-01-26

Applicant: 3M INNOVATIVE PROPERTIES COMPANY

Inventor： Yizhong Wang ,  Ta-Hua Yu ,  Joel D. Oxman ,  Richard P. Rusin

IPC: A61K33/18 ,  A61K8/21 ,  A61K33/16 ,  A61K33/38 ,  A61K9/08 ,  A61Q11/00 ,  A61Q11/02 ,  A61K8/46

CPC classification number: A61K8/21 ,  A61K8/46 ,  A61Q11/00 ,  A61Q11/02 ,  A61K2800/5424 ,  A61K2800/5426 ,  A61K2800/92

Abstract: An aqueous oral care one-part composition (e.g., solution), a kit that includes such composition (e.g., solution), and methods (e.g., a method of providing fluoride to a patient's tooth surface), wherein the oral care composition (e.g., solution) includes: silver cations; iodide anions; fluoride anions; and water.

公开(公告)号：US20230134622A1

公开(公告)日：2023-05-04

申请号：US17247244

申请日：2019-06-04

Applicant: 3M INNOVATIVE PROPERTIES COMPANY

Inventor： Randilynn B. Christensen ,  Kenton D. Budd ,  Afshin Falsafi ,  Mahmut Aksit ,  Jana Ninkovic ,  Jie J. Liu ,  Mark B. Agre ,  Masayuki Nakamura ,  Jason W. Bjork ,  Bradley D. Craig ,  Richard P. Rusin ,  Paul J. Homnick ,  Joel D. Oxman ,  Yizhong Wang ,  Paul R. Klaiber ,  Bill H. Dodge

IPC: A61C5/64 ,  A61K6/887 ,  A61K6/79 ,  A61K6/61 ,  A61K6/62

Abstract: A method of applying a two-part dental sealant is described comprising providing a syringe device (1) comprising a cartridge (10) including first and second chamber. The first chamber contains a first part of a dental sealant comprising a (meth)acrylate resin and an oxidizing curing agent. The second chamber contains a second part of a dental sealant comprising a (meth)acrylate resin and a reducing curing agent that reacts with the oxidizing curing agent of the first chamber. The first and/or second part of the dental sealant further comprise a single component or multiple components that neutralize acid and promote remineralization. The syringe device comprises a dispensing nozzle (17) comprising a static mixer and an outlet at one end of the cartridge and a plunger (20) at the opposing end of the cartridge. Also described is a kit for storing and applying the dental sealant is described.

公开(公告)号：US20210290501A1

公开(公告)日：2021-09-23

申请号：US17250351

申请日：2019-07-25

Applicant: 3M INNOVATIVE PROPERTIES COMPANY

Inventor： Yizhong Wang ,  Ta-Hua Yu ,  Joel D. Oxman ,  Richard P. Rusin

IPC: A61K8/21 ,  A61Q11/00 ,  A61K8/46

Abstract: An aqueous oral care one-part composition (e.g., solution), a kit that includes such composition (e.g., solution), and methods (e.g., a method of providing fluoride to a patients tooth surface), wherein the oral care composition (e.g., solution) includes: silver cations; thiocyanate anions; fluoride anions; and water.

公开(公告)号：US20190282471A1

公开(公告)日：2019-09-19

申请号：US16302394

申请日：2017-05-22

Applicant: 3M INNOVATIVE PROPERTIES COMPANY

Inventor： Jie Yang ,  Richard P. Rusin ,  Petra L. Kohler Riedi ,  Joel D. Oxman ,  Jodi L. Connell

IPC: A61K8/25 ,  A61K8/41 ,  A61K8/42 ,  A61K8/44 ,  A61K8/24 ,  A61Q11/00

Abstract: Dental pastes are provided which include: (i) a compound of Formula (I), (ii) a compound of Formula (II) or a pharmaceutically acceptable salt thereof, and (iii) a dental abrasive.

公开(公告)号：US20140193777A1

公开(公告)日：2014-07-10

申请号：US14208055

申请日：2014-03-13

Applicant: 3M INNOVATIVE PROPERTIES COMPANY

Inventor： Richard P. Rusin ,  Sumita B. Mitra ,  Kevin M. Cummings

IPC: A61K6/00

CPC classification number: A61K6/0082 ,  A61K6/0017 ,  A61K6/0023 ,  A61K6/0029 ,  A61K6/0047 ,  A61K6/0073 ,  A61K6/0088 ,  A61K6/0091 ,  A61K6/0205 ,  A61K6/083 ,  C08L33/00

Abstract: The present application provides dental fillers, and methods of making and using dental fillers that include a treated surface that includes phosphorus and a divalent cation. Dental compositions including such dental fillers can be useful for delivering ions to the oral environment.

Abstract translation: 本申请提供牙科填料，以及制造和使用包括磷和二价阳离子的处理表面的牙科填料的方法。 包括这种牙科填料的牙科组合物可用于将离子输送到口腔环境中。

公开(公告)号：US20240000675A1

公开(公告)日：2024-01-04

申请号：US18469859

申请日：2023-09-19

Applicant: 3M INNOVATIVE PROPERTIES COMPANY

Inventor： Yizhong WANG ,  Ta-Hua Yu ,  Joel D. Oxman ,  Richard P. Rusin

IPC: A61K8/21 ,  A61Q11/02 ,  A61K8/46 ,  A61Q11/00

CPC classification number: A61K8/21 ,  A61Q11/02 ,  A61K8/46 ,  A61Q11/00 ,  A61K2800/5424 ,  A61K2800/5426 ,  A61K2800/92

Abstract: An aqueous oral care one-part composition (e.g., solution), a kit that includes such composition (e.g., solution), and methods (e.g., a method of providing fluoride to a patient's tooth surface), wherein the oral care composition (e.g., solution) includes: silver cations; iodide anions; fluoride anions; and water.

公开(公告)号：US09296767B1

公开(公告)日：2016-03-29

申请号：US14943170

申请日：2015-11-17

Applicant: 3M INNOVATIVE PROPERTIES COMPANY

Inventor： Richard P. Rusin ,  Neeraj Sharma ,  Sumita B. Mitra

IPC: C07F9/141

CPC classification number: C07F9/1411 ,  A61K8/11 ,  A61K8/19 ,  A61K8/345 ,  A61K8/55 ,  A61K8/69 ,  A61Q11/00

Abstract: Calcium phosphate particles are described comprising a surface treatment wherein the surface treatment comprises at least one sugar alcohol. Also described are various oral care compositions comprising surface treated calcium phosphate particles and methods of surface treating calcium phosphate particles.

公开(公告)号：US09233054B2

公开(公告)日：2016-01-12

申请号：US14208055

申请日：2014-03-13

Applicant: 3M INNOVATIVE PROPERTIES COMPANY

Inventor： Richard P. Rusin ,  Sumita B. Mitra ,  Kevin M. Cummings

IPC: A61K6/083 ,  A61K6/00

CPC classification number: A61K6/0082 ,  A61K6/0017 ,  A61K6/0023 ,  A61K6/0029 ,  A61K6/0047 ,  A61K6/0073 ,  A61K6/0088 ,  A61K6/0091 ,  A61K6/0205 ,  A61K6/083 ,  C08L33/00

Abstract: The present application provides dental fillers, and methods of making and using dental fillers that include a treated surface that includes phosphorus and a divalent cation. Dental compositions including such dental fillers can be useful for delivering ions to the oral environment.

Abstract translation: 本申请提供牙科填料，以及制造和使用包括磷和二价阳离子的处理表面的牙科填料的方法。 包括这种牙科填料的牙科组合物可用于将离子输送到口腔环境中。

公开(公告)号：USD716456S1

公开(公告)日：2014-10-28

申请号：US29443584

申请日：2013-01-18

Applicant: 3M Innovative Properties Company

Designer： Richard P. Rusin ,  Brady P. Haislet ,  Darin J. Meyertholen

公开(公告)号：US11696879B2

公开(公告)日：2023-07-11

申请号：US16302394

申请日：2017-05-22

Applicant: 3M INNOVATIVE PROPERTIES COMPANY

Inventor： Jie Yang ,  Richard P. Rusin ,  Petra L. Kohler Riedi ,  Joel D. Oxman ,  Jodi L. Connell

IPC: A61K8/25 ,  A61K8/24 ,  A61K8/41 ,  A61K8/42 ,  A61K8/44 ,  A61Q11/00

CPC classification number: A61K8/25 ,  A61K8/24 ,  A61K8/41 ,  A61K8/42 ,  A61K8/44 ,  A61Q11/00 ,  A61K2800/87 ,  A61K2800/88

Abstract: Dental pastes are provided which include: (i) a compound of Formula (I), (ii) a compound of Formula (II) or a pharmaceutically acceptable salt thereof, and (iii) a dental abrasive.