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公开(公告)号：US20220030860A1
公开(公告)日：2022-02-03
申请号：US17263663
申请日：2019-08-05
摘要： A composition. The composition includes a compound of Formula (I) HOCH2—(═CHOH═)n—CH2NR1R2 (I) wherein R1 and R2 are independently selected from the group consisting of a hydrogen atom, an alkyl group, C(O)R3, and SO2R4, wherein at least one of R1 and R2 is C(O)R3 or SO2R4, R3 and R4 are selected from the group consisting of an alkyl group having seven carbon atoms, an alkyl group having eight carbon atoms, and an alkyl group having nine carbon atoms, and n is an integer from about 2 to about wherein a concentration of the compound of Formula (I) is more than its critical micelle concentration; and an antimicrobial agent selected from the group consisting of a biguanide antimicrobial agent and a polymeric, cationic, non-micelle forming antimicrobial material; wherein a concentration of the antimicrobial agent is no more than 5 wt %.
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公开(公告)号：US20190282471A1
公开(公告)日：2019-09-19
申请号：US16302394
申请日：2017-05-22
摘要： Dental pastes are provided which include: (i) a compound of Formula (I), (ii) a compound of Formula (II) or a pharmaceutically acceptable salt thereof, and (iii) a dental abrasive.
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公开(公告)号：US08647608B2
公开(公告)日：2014-02-11
申请号：US13664452
申请日：2012-10-31
发明人： Jie Yang , Bhaskar V. Velamakanni , Sumita B. Mitra , Alphonsus V. Pocius , John J. Stofko, Jr. , Jeremy M. Yarwood
IPC分类号： A61K8/41 , A61K8/42 , A61K8/85 , A61K8/87 , A61K8/89 , A61Q11/00 , C07C215/10 , C07C233/18
摘要： Dental compositions are provided comprising a compound of Formula I or a pharmaceutically acceptable salt thereof: wherein n is an integer from about 2 to about 5.
摘要翻译： 提供牙科组合物，其包含式I化合物或其药学上可接受的盐：其中n为约2至约5的整数。
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公开(公告)号：US20200368128A1
公开(公告)日：2020-11-26
申请号：US16767634
申请日：2018-11-26
IPC分类号： A61K8/41 , C11D1/29 , C11D3/10 , C11D3/30 , C11D17/00 , C11D17/06 , A61K8/19 , A61Q11/02 , A61K8/02
摘要： Disclosed herein are cleaning compositions effective for cleaning an oral appliance or device. The cleaning composition can include: (i) a compound of Formula (I): wherein R1 is a hydrogen atom or an alkyl group, R2 is C(O)R3, R3 is a C7-C9 alkyl group, and n is an integer from 2 to 5; and (ii) a second component selected from the group consisting of persulfate (e.g., peroxymonosulfate and peroxydisulfate) salts, percarbonate salts, perborate salts, hypochlorite salts, dichloroisocyanurate salts, trichloroisocyanurate salts, tetraacetylethylenediamine, perphosphate salts, and combinations thereof. Optionally, the cleaning composition can further include water.
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公开(公告)号：US20200330347A1
公开(公告)日：2020-10-22
申请号：US16955224
申请日：2018-12-18
发明人： Katie F. Wlaschin , Amanda C. Engler , Hannah C. Cohen , Yizhong Wang , Tao Gong , Tiffany T. Ton , Joel D. Oxman , Jie Yang
IPC分类号： A61K8/36 , A61K8/92 , A61K8/73 , A61K8/9794 , A61K8/42 , A61K8/67 , A61K8/49 , A61K8/365 , A61Q11/00
摘要： Compositions that include: from 5 wt-% to 70 wt-% of one or more plant based oils based on the total weight of the composition; from 35 wt-% to 95 wt-% of an aqueous phase based on the total weight of the composition; not greater than 7.5 wt-% of one or more surfactants based on the total weight of the composition; and not greater than 3 wt-% of a viscosity modifier of, wherein the composition has a pH from 4.5 to 9.5, the composition is an oil in water (o/w) emulsion, and the composition is edible. Methods of utilizing disclosed compositions are also included.
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公开(公告)号：US20180071053A1
公开(公告)日：2018-03-15
申请号：US15559212
申请日：2016-03-21
发明人： Jie Yang , Naimul Karim , Todd D. Jones , Dwight W. Jacobs , Steven Keck , Kristen Keller , Richard Yufeng Liu
IPC分类号： A61C5/77 , A61C13/087
摘要： A method of using hardenable dental articles. The method can include placing a film (30) onto a dental structure (40) to cover at least a portion of the dental structure (40); providing a hardenable dental article (10); and applying the hardenable dental article (10) to the dental structure (40) covered by the film (30).
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公开(公告)号：US08552086B2
公开(公告)日：2013-10-08
申请号：US13719692
申请日：2012-12-19
发明人： Naimul Karim , Todd D. Jones , Kevin M. Lewandowski , Bradley D. Craig , Sumita B. Mitra , Jie Yang
CPC分类号： A61K6/08 , A61C5/70 , A61K6/0662 , A61K6/083 , A61K6/087 , Y10S977/919
摘要： A hardenable dental composition that includes a polymerizable component and an organogelator.
摘要翻译： 包含可聚合组分和有机凝胶剂的可硬化牙科组合物。
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公开(公告)号：US20130109780A1
公开(公告)日：2013-05-02
申请号：US13719692
申请日：2012-12-19
发明人： Naimul Karim , Todd D. Jones , Kevin M. Lewandowski , Bradley D. Craig , Sumita B. Mitra , Jie Yang
IPC分类号： A61K6/08
CPC分类号： A61K6/08 , A61C5/70 , A61K6/0662 , A61K6/083 , A61K6/087 , Y10S977/919
摘要： A hardenable dental composition that includes a polymerizable component and an organogelator.
摘要翻译： 包含可聚合组分和有机凝胶剂的可硬化牙科组合物。
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公开(公告)号：US11801231B2
公开(公告)日：2023-10-31
申请号：US16226122
申请日：2018-12-19
发明人： Katie F. Wlaschin , Amanda C. Engler , Hannah C. Cohen , Yizhong Wang , Tao Gong , Tiffany T. Ton , Joel D. Oxman , Jie Yang
IPC分类号： A61K31/164 , A61K9/00 , A61K9/107 , A61K47/02 , A61K47/10 , A61P1/02 , A61K47/26 , A61K47/44
CPC分类号： A61K31/164 , A61K9/0053 , A61K9/107 , A61K47/02 , A61K47/10 , A61K47/26 , A61K47/44 , A61P1/02
摘要： Compositions that include from 0.1 wt-% to 8 wt-% of one or more compounds of formula (I) based on the total weight of the composition
HOCH2—(CHOH)n—CH2NR1R2 (I)
wherein R1 and R2 are independently selected from the group consisting of a hydrogen atom, an alkyl group, C(O)R3, and SO2R4; with R3 and R4 being independently selected from the group consisting of an alkyl group, an aryl group, and an aralkyl group; wherein n is an integer from about 2 to about 5; from 5 wt-% to 95 wt-% of one or more plant based oils based on the total weight of the composition; from 5 wt-% to 80 wt-% water based on the total weight of the composition and from 0.01 wt-% to 1 wt-% of one or more nonionic aromatic phenolic preservatives based on the total weight of the composition wherein the composition has a pH from 4.5 to 9.5, the composition is an emulsion, and the composition is edible.
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