公开(公告)号：US20150276710A1

公开(公告)日：2015-10-01

申请号：US14666606

申请日：2015-03-24

Applicant: AJINOMOTO CO., INC.

Inventor： Seiji Kitajima ,  Yutaka Ishiwatari

IPC: G01N33/50 ,  C07K14/72

CPC classification number: G01N33/502 ,  C07K14/705 ,  C07K14/723 ,  C07K2319/00 ,  G01N2333/705 ,  G01N2500/02

Abstract: A sweet taste substance or a sweet taste-regulating substance is detected by contacting a test substance with a cell that expresses a chimeric protein of human T1R2 and mouse T1R2, and/or a chimeric protein of human T1R3 and mouse T1R3, and may further express a G protein α subunit, and by detecting an interaction between the chimeric proteins and the test substance.

Abstract translation: 通过使测试物质与表达人T1R2和小鼠T1R2的嵌合蛋白的细胞和/或人T1R3和小鼠T1R3的嵌合蛋白接触来检测甜味物质或甜味调节物质，并且可进一步表达 G蛋白α亚单位，并通过检测嵌合蛋白质和测试物质之间的相互作用。

公开(公告)号：US20140004243A1

公开(公告)日：2014-01-02

申请号：US14019993

申请日：2013-09-06

Applicant: AJINOMOTO CO., INC.

Inventor： Yuki TAHARA ,  Yusuke Amino ,  Takami Maekawa ,  Yuzuru Eto ,  Takashi Miyaki ,  Wakana Saikawa ,  Yuko Kai ,  Yutaka Ishiwatari

IPC: A23L1/237

CPC classification number: A23L27/88 ,  A23L27/40 ,  C07C335/12 ,  C07D209/14 ,  C07D209/16 ,  C07D209/44 ,  C07D213/40 ,  C07D217/06 ,  C07D233/86 ,  C07D235/14 ,  C07D307/52 ,  C07D317/58

Abstract: The present invention provides a compound having a salty taste enhance activity, and a salty taste enhancer containing the compound, and the like.The present invention relates to a salty taste enhancer for a food or drink, which contains a compound represented by the following formula: wherein each symbol is as defined in the specification, or an edible salt thereof.

Abstract translation: 本发明提供具有咸味增强活性的化合物和含有该化合物的咸味增强剂等。 本发明涉及食品或饮料的咸味增强剂，其含有下式表示的化合物：其中各符号如说明书中所定义，或其食用盐。

公开(公告)号：US09341616B2

公开(公告)日：2016-05-17

申请号：US14666606

申请日：2015-03-24

Applicant: AJINOMOTO CO., INC.

Inventor： Seiji Kitajima ,  Yutaka Ishiwatari

IPC: C07K14/705 ,  C07K19/00 ,  G01N33/557 ,  G01N33/50 ,  C07K14/72

CPC classification number: G01N33/502 ,  C07K14/705 ,  C07K14/723 ,  C07K2319/00 ,  G01N2333/705 ,  G01N2500/02

Abstract: A sweet taste substance or a sweet taste-regulating substance is detected by contacting a test substance with a cell that expresses a chimeric protein of human T1R2 and mouse T1R2, and/or a chimeric protein of human T1R3 and mouse T1R3, and may further express a G protein α subunit, and by detecting an interaction between the chimeric proteins and the test substance.

Abstract translation: 通过使测试物质与表达人T1R2和小鼠T1R2的嵌合蛋白的细胞和/或人T1R3和小鼠T1R3的嵌合蛋白接触来检测甜味物质或甜味调节物质，并且可进一步表达 G蛋白α亚单位，并通过检测嵌合蛋白质和测试物质之间的相互作用。

公开(公告)号：US20130196050A1

公开(公告)日：2013-08-01

申请号：US13852434

申请日：2013-03-28

Applicant: AJINOMOTO CO., INC.

Inventor： Yusuke AMINO ,  Takami Maekawa ,  Yuzuru Eto ,  Megumi Kaneko ,  Yuki Tahara ,  Takashi Miyaki ,  Wakana Saikawa ,  Yuko Kai ,  Yutaka Ishiwatari

IPC: A23L1/221 ,  C07D209/22

CPC classification number: C07D209/14 ,  A23L27/204 ,  A23L27/2054 ,  A23L27/88 ,  C07C233/51 ,  C07C235/38 ,  C07C235/60 ,  C07C237/20 ,  C07C309/51 ,  C07D209/16 ,  C07D209/18 ,  C07D209/20 ,  C07D317/48 ,  C07D317/60 ,  C07D487/04

Abstract: Compounds represented by formula (I): wherein each symbol is as defined in the specification, exhibit a salty taste enhancing activity and are useful as salty taste enhancers for foods and drinks.

Abstract translation: 由式（I）表示的化合物：其中每个符号如说明书中所定义，表现出咸味增强活性，并且可用作食品和饮料的咸味增强剂。