公开(公告)号：US11826578B2

公开(公告)日：2023-11-28

申请号：US17559017

申请日：2021-12-22

Applicant: AJOU UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION

Inventor： Chul Ho Kim ,  Sung Un Kang ,  Jae Won Choi

IPC: A61N1/44 ,  A61K33/00 ,  C12N5/077

CPC classification number: A61N1/44 ,  A61K33/00 ,  C12N5/0658 ,  C12N2500/02

Abstract: The present invention relates to a method for producing a nitrogen-based non-thermal atmospheric pressure plasma for treating damaged muscles or promoting regeneration of damaged muscles, and to a method for treating damaged muscle or promoting regeneration of damaged muscles using the atmospheric pressure plasma. The nitrogen-based non-thermal atmospheric pressure plasma according to the present invention can effectively induce muscle cell activation, migration of muscle cells to damaged sites, muscle cell proliferation, and muscle cell differentiation, without surgical operation or during a treatment procedure after surgical operation, and thus can be advantageously used as a novel therapeutic agent and therapeutic method against muscle damage and muscle damage-associated diseases.

公开(公告)号：US10537014B2

公开(公告)日：2020-01-14

申请号：US16335925

申请日：2017-09-19

Applicant: AJOU UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION

Inventor： Chul Ho Kim ,  Sung Un Kang

IPC: H05H1/24 ,  A61P3/04 ,  A61K9/00

Abstract: Provided is a composition for obesity treatment comprising a liquid-phase plasma. More particularly, provided is a method for producing a liquid-phase plasma for inhibiting adipocyte differentiation or proliferation, a pharmaceutical composition for obesity prevention or treatment using a liquid-phase plasma produced according to the method, and a method for obesity prevention or treatment using the liquid-phase plasma.

公开(公告)号：US11759407B2

公开(公告)日：2023-09-19

申请号：US16464180

申请日：2017-11-13

Applicant: AJOU UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION

Inventor： Chul Ho Kim ,  Sung Un Kang

IPC: A61B18/00 ,  A61K8/02 ,  A61K8/64 ,  A61K8/22 ,  A61K38/18 ,  A61P17/02 ,  A61K47/02 ,  A61Q19/02

CPC classification number: A61K8/0204 ,  A61K8/22 ,  A61K8/64 ,  A61K38/1808 ,  A61K38/1825 ,  A61K38/1841 ,  A61K38/1858 ,  A61K47/02 ,  A61P17/02 ,  A61Q19/02

Abstract: The present invention relates to a composition for skin whitening or wound treatment including liquid-type plasma, and more particularly, to a cosmetic composition for skin whitening and a pharmaceutical composition for treating and preventing skin pigmentation diseases which contain liquid-type plasma as an active ingredient. In addition, the present invention relates to a pharmaceutical composition for wound treatment, a quasi-drug composition, and a health functional food composition, which include liquid-type plasma and a growth factor as active ingredients, and a wound treatment method including a step of administering the composition to a subject or a step of applying the composition on the skin. The composition including liquid-type plasma and a growth factor of the present invention is capable of inducing the proliferation of fibroblasts, thereby exhibiting excellent wound treatment efficacy. Accordingly, the composition including liquid-type plasma and a growth factor of the present invention can be usefully applied to medicines including external preparations for wound treatment, etc.

公开(公告)号：US11684793B2

公开(公告)日：2023-06-27

申请号：US16648883

申请日：2018-07-27

Applicant: AJOU UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION

Inventor： Chul Ho Kim ,  Sung Un Kang

IPC: C07H21/04 ,  C07H21/02 ,  A61N1/44 ,  A61P17/02 ,  A61K31/713 ,  H05H1/24 ,  C12N15/113 ,  A61K48/00 ,  A61M11/00

CPC classification number: A61N1/44 ,  A61K31/713 ,  A61K48/00 ,  A61P17/02 ,  C12N15/1138 ,  H05H1/24 ,  A61M11/00 ,  H05H2245/30

Abstract: The present invention relates to a non-thermal atmospheric-pressure plasma keloid treatment device and a use thereof. The non-thermal atmospheric-pressure plasma keloid treatment device according to the present invention has effects of inhibiting collagen deposition in keloid fibroblasts and mobility thereof, and thus, is expected to be greatly useful for preventing and treating keloids.

公开(公告)号：US11246885B2

公开(公告)日：2022-02-15

申请号：US16643418

申请日：2018-08-23

Applicant: AJOU UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION

Inventor： Chul Ho Kim ,  Sung Un Kang

IPC: A61K33/00 ,  A61P17/02

Abstract: The present invention relates to a method of preventing or treating keloids using a liquid plasma. A liquid plasma according to the present invention is remarkably effective in inhibiting the generation and proliferation of keloids, thus being expected to be greatly utilized for the prevention and treatment of keloids.