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公开(公告)号：US12105771B2
公开(公告)日：2024-10-01
申请号：US17455513
申请日：2021-11-18
Inventor： Jae Sung Heo , Chul Ho Kim
IPC: G06F18/214 , G06N20/00 , G06T7/00 , G16H30/20
CPC classification number: G06F18/214 , G06N20/00 , G06T7/0012 , G16H30/20 , G06T2207/10068 , G06T2207/30036 , G06T2207/30096 , G06V2201/03
Abstract: Disclosed are an apparatus and method for generating training data. An apparatus for generating training data according to an embodiment includes a reading result acquirer that acquires one or more oral endoscopic images and clinical information related to each of the one or more oral endoscopic images, provides the one or more oral endoscopic images and the clinical information to a user terminal of each of a plurality of preset medical staffs, and receives a reading result for each of the one or more oral endoscopic images from the user terminal of each of the plurality of medical staffs, and a labeling unit that selects one or more labeling target images from among the one or more oral endoscopic images based on the reading result received from the user terminal of each of the plurality of medical staffs and determines one or more labels for each of the one or more labeling target images based on the reading result.
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公开(公告)号：US11510853B2
公开(公告)日：2022-11-29
申请号：US16648087
申请日：2018-09-17
Inventor： Chul Ho Kim , Kyoungwon Jung
Abstract: The present invention is to provide a composition for skin soothing, which is safe from a risk of side effects, and relates to a composition for skin soothing containing a liquid-phase plasma. The liquid-phase plasma of the present invention is obtained by applying plasma as pure energy to a liquid-phase material, and can be used in the skin sensitive to a chemical material without a risk of side effects. Furthermore, the liquid-phase plasma has remarkable effects on the prevention or treatment of dermatitis or photo-aging due to ultraviolet light, and thus is expected to be greatly used in beauty care and mechanical fields.
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公开(公告)号：US10537014B2
公开(公告)日：2020-01-14
申请号：US16335925
申请日：2017-09-19
Inventor： Chul Ho Kim , Sung Un Kang
Abstract: Provided is a composition for obesity treatment comprising a liquid-phase plasma. More particularly, provided is a method for producing a liquid-phase plasma for inhibiting adipocyte differentiation or proliferation, a pharmaceutical composition for obesity prevention or treatment using a liquid-phase plasma produced according to the method, and a method for obesity prevention or treatment using the liquid-phase plasma.
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公开(公告)号：US08772493B2
公开(公告)日：2014-07-08
申请号：US13711376
申请日：2012-12-11
Applicant: Ajou University Industry-Academic Cooperation Foundation , Korea Research Institute of Chemical Technology
Inventor： Chul Ho Kim , Young Sik Jung
IPC: A01N43/42 , A01N43/40 , A61K31/44 , A61K31/445 , A61K31/47 , C07D215/00 , C07D211/08 , C07D401/00 , C07D211/40 , C07D419/00
CPC classification number: C07D215/38 , A23L33/10 , C07C231/02 , C07C233/55
Abstract: The present invention relates to a compound represented by formula 1 in the present specification or a pharmaceutically acceptable thereof, which inhibits an apoptosis mechanism of auditory hair cells for various ototoxicities leading to deafness, and protects the auditory organ and hearing, a method for preparation thereof, and a composition containing the same.
Abstract translation: 本发明涉及本说明书中由式1表示的化合物或其药学上可接受的物质，其抑制导致耳聋的各种耳毒性的听觉毛细胞的凋亡机制，并且保护听觉器官和听觉，其制备方法 ，以及含有该组合物的组合物。
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公开(公告)号：US20130217881A1
公开(公告)日：2013-08-22
申请号：US13711376
申请日：2012-12-11
Applicant: Ajou University Industry-Academic Cooperation Foundation , Korea Research Institute of Chemical Technology
Inventor： Chul Ho Kim , Young Sik Jung
IPC: C07D215/38
CPC classification number: C07D215/38 , A23L33/10 , C07C231/02 , C07C233/55
Abstract: The present invention relates to a compound represented by formula 1 in the present specification or a pharmaceutically acceptable thereof, which inhibits an apoptosis mechanism of auditory hair cells for various ototoxicities leading to deafness, and protects the auditory organ and hearing, a method for preparation thereof, and a composition containing the same.
Abstract translation: 本发明涉及本说明书中由式1表示的化合物或其药学上可接受的物质，其抑制导致耳聋的各种耳毒性的听觉毛细胞的凋亡机制，并且保护听觉器官和听觉，其制备方法 ，以及含有该组合物的组合物。
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Patent Agency Ranking
公开(公告)号：US11826578B2
公开(公告)日：2023-11-28
申请号：US17559017
申请日：2021-12-22
Inventor： Chul Ho Kim , Sung Un Kang , Jae Won Choi
CPC classification number: A61N1/44 , A61K33/00 , C12N5/0658 , C12N2500/02
Abstract: The present invention relates to a method for producing a nitrogen-based non-thermal atmospheric pressure plasma for treating damaged muscles or promoting regeneration of damaged muscles, and to a method for treating damaged muscle or promoting regeneration of damaged muscles using the atmospheric pressure plasma. The nitrogen-based non-thermal atmospheric pressure plasma according to the present invention can effectively induce muscle cell activation, migration of muscle cells to damaged sites, muscle cell proliferation, and muscle cell differentiation, without surgical operation or during a treatment procedure after surgical operation, and thus can be advantageously used as a novel therapeutic agent and therapeutic method against muscle damage and muscle damage-associated diseases.
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公开(公告)号：US09750951B2
公开(公告)日：2017-09-05
申请号：US14982948
申请日：2015-12-29
Inventor： Chul Ho Kim , Sun Yong Kim
CPC classification number: A61N1/44 , A61K33/00 , H05H1/24 , H05H2240/20 , H05H2245/122
Abstract: The present invention relates to a method for preparing a plasma for preventing or treating a cancer. Also, the present invention relates to a liquid type plasma for preventing or treating a cancer prepared by treating the plasma and a pharmaceutical composition for preventing or treating a cancer comprising the same. The plasma and the liquid type plasma according to the present invention can effectively induce cancer cell death without a surgical operation or in a treatment process after a surgical operation, thereby being useful as a novel therapeutic agent and method for a cancer.
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公开(公告)号：US20160296763A1
公开(公告)日：2016-10-13
申请号：US14982948
申请日：2015-12-29
Inventor： Chul Ho Kim , Sun Yong Kim
CPC classification number: A61N1/44 , A61K33/00 , H05H1/24 , H05H2240/20 , H05H2245/122
Abstract: The present invention relates to a method for preparing a plasma for preventing or treating a cancer. Also, the present invention relates to a liquid type plasma for preventing or treating a cancer prepared by treating the plasma and a pharmaceutical composition for preventing or treating a cancer comprising the same. The plasma and the liquid type plasma according to the present invention can effectively induce cancer cell death without a surgical operation or in a treatment process after a surgical operation, thereby being useful as a novel therapeutic agent and method for a cancer.
Abstract translation: 本发明涉及一种预防或治疗癌症的血浆的制备方法。 另外，本发明涉及一种用于预防或治疗通过治疗血浆而制备的癌症的液体型等离子体，以及用于预防或治疗包含该癌症的癌症的药物组合物。 根据本发明的等离子体和液体型等离子体可以在外科手术或外科手术后的治疗过程中有效地诱导癌细胞死亡，从而可用作癌症的新治疗剂和方法。
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公开(公告)号：US11759407B2
公开(公告)日：2023-09-19
申请号：US16464180
申请日：2017-11-13
Inventor： Chul Ho Kim , Sung Un Kang
CPC classification number: A61K8/0204 , A61K8/22 , A61K8/64 , A61K38/1808 , A61K38/1825 , A61K38/1841 , A61K38/1858 , A61K47/02 , A61P17/02 , A61Q19/02
Abstract: The present invention relates to a composition for skin whitening or wound treatment including liquid-type plasma, and more particularly, to a cosmetic composition for skin whitening and a pharmaceutical composition for treating and preventing skin pigmentation diseases which contain liquid-type plasma as an active ingredient. In addition, the present invention relates to a pharmaceutical composition for wound treatment, a quasi-drug composition, and a health functional food composition, which include liquid-type plasma and a growth factor as active ingredients, and a wound treatment method including a step of administering the composition to a subject or a step of applying the composition on the skin. The composition including liquid-type plasma and a growth factor of the present invention is capable of inducing the proliferation of fibroblasts, thereby exhibiting excellent wound treatment efficacy. Accordingly, the composition including liquid-type plasma and a growth factor of the present invention can be usefully applied to medicines including external preparations for wound treatment, etc.
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公开(公告)号：US11684793B2
公开(公告)日：2023-06-27
申请号：US16648883
申请日：2018-07-27
Inventor： Chul Ho Kim , Sung Un Kang
IPC: C07H21/04 , C07H21/02 , A61N1/44 , A61P17/02 , A61K31/713 , H05H1/24 , C12N15/113 , A61K48/00 , A61M11/00
CPC classification number: A61N1/44 , A61K31/713 , A61K48/00 , A61P17/02 , C12N15/1138 , H05H1/24 , A61M11/00 , H05H2245/30
Abstract: The present invention relates to a non-thermal atmospheric-pressure plasma keloid treatment device and a use thereof. The non-thermal atmospheric-pressure plasma keloid treatment device according to the present invention has effects of inhibiting collagen deposition in keloid fibroblasts and mobility thereof, and thus, is expected to be greatly useful for preventing and treating keloids.
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