Synthesis of gramine salt of nitroacetate esters
    6.
    发明授权
    Synthesis of gramine salt of nitroacetate esters 失效
    硝酸纤维素盐的合成

    公开(公告)号:US3627782A

    公开(公告)日:1971-12-14

    申请号:US3627782D

    申请日:1969-06-12

    Applicant: ALLIED CHEM

    Inventor: LARGMAN THEODORE

    CPC classification number: C07D209/20

    Abstract: Tryptophan, an essential amino acid, is prepared from gramine and an ester of nitroacetic acid by combining gramine and the ester in an inert solvent maintained at about room temperature to form the corresponding salt, and then heating the salt in solution to convert it to the corresponding ester of Alpha nitro- Beta - (3-indole) propionic acid, which is reduced and hydrolyzed in accordance with conventional methods to afford tryptophan. The salt is a novel compound.

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