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1.发明授权Method of treating neisseria infections with 6-{8 2-(3-amidinoureido)-2-phenyl acetamido{9 penicillanic acid 失效用6- {8 2-（3-脒基脲基）-2-苯基乙酰氨基{9青霉烷酸治疗奈瑟氏菌感染的方法
公开(公告)号：US3867537A
公开(公告)日：1975-02-18
申请号：US18459071
申请日：1971-09-28
Applicant: AMERICAN HOME PROD
Inventor： ALBURN HARVEY E
IPC: C07D499/00 , A61K21/00
CPC classification number: C07D499/00
Abstract: A method for treating infections caused by the Neisseria genus is described using an effective amount of 6-(2-(3-amidinoureido)-2-phenyl acetamido)penicillanic acid.
Abstract translation: 使用有效量的6- [2-（3-脒基 - 脲基）-2-苯基乙酰氨基]青霉烷酸描述治疗由奈瑟氏球菌引起的感染的方法。
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公开(公告)号：US3655725A
公开(公告)日：1972-04-11
申请号：US3655725D
申请日：1970-10-16
Applicant: AMERICAN HOME PROD
Inventor： ALBURN HARVEY E , DVONCH WILLIAM
IPC: C07C101/36
CPC classification number: C07C2601/08
Abstract: THE PHENYL, MENTHYL, AND CHOLINE HALIDE ESTER OF 1AMINOCYCLOPENTANECARBOXYLIC ACID ARE PHARMACOLOGICALLY ACTIVE, SHOWING THE ABILITY TO BLOCK THE IMMUNE RESPONSE IN WARM-BLOODED ANIMALS.
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公开(公告)号：US3629391A
公开(公告)日：1971-12-21
申请号：US3629391D
申请日：1969-04-28
Applicant: AMERICAN HOME PROD
Inventor： FENICHEL RICHARD L , ALBURN HARVEY E
CPC classification number: C07K14/62 , A61K38/00 , Y10T436/144444
Abstract: COMPOSITION CONTAINING REDUCED INSULIN B CHAINS COMPLEXED WITH ALBUMIA HAVE HYPERGLYCEMIC ACTIVITY AND ARE USEFUL IN THE TREATMENT OF HYPERINSULINISM, TO SCREEN SUBSTANCES WHICH ARE USEFUL IN THE TREATMENT OF DIABETES AND TO DIAGNOSE DIABETIC AND STATES IN ANIMALS.
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4.发明授权
公开(公告)号：US3594366A
公开(公告)日：1971-07-20
申请号：US3594366D
申请日：1968-11-26
Applicant: AMERICAN HOME PROD
Inventor： GRANT NORMAN H , CLARK DONALD E , ALBURN HARVEY E
IPC: C07D499/00 , C07D499/74 , C07D99/16
CPC classification number: C07D499/00
Abstract: 6-(1-AMINOCYCLOALKANECARBOXAMIDO) AND 6-(1-AMINOARYLCYCLOALKANECARBOXAMIDO) PENICILLANIC ACIDS WITH BROAD SPECTRUM ANTIBACTERIAL ACTIVITY ARE OBTAINED RAPIDLY AND IN HIGH YIELD, WITHOUT THE NEED TO ISOLATE THEM FROM DILUTE SOLUTIONS, BY AN IMPROVED PROCESS COMPRISING CONDENSING AND PRECIPITATING IN ONE STEP THE PRODUCT FROM THE ADDITION OF AN N-CARBOXYANHYDRIDE OF AN AMINO ACID TO A HIGHLY CONCENTRATED, E.G. 5-40% BY WEIGHT, AQUEOUS SUSPENSION OF 6-AMINOPENICILLANIC ACID.
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5.发明授权6-(indan - 2 - amino - 2 - carboxamido) and 6 - (1,2,3,4 - tetrahydronaphthalene - 2-amino - 2 - carboxamido) penicillanic acids 失效6-（INDAN-2-氨基-2-羧基甲酰胺）和6-（1,2,3,4-四氢萘基-2-氨基-2-羧基甲酰胺）苯胺酸
公开(公告)号：US3494915A
公开(公告)日：1970-02-10
申请号：US3494915D
申请日：1967-07-28
Applicant: AMERICAN HOME PROD
Inventor： ALBURN HARVEY E , CLARK DONALD E , GRANT NORMAN H , RUSSELL PETER B
IPC: C07C45/28 , C07D235/02 , C07D263/52 , C07D499/00 , C07D499/12 , C07D499/74 , C07D99/16 , A61K21/00
CPC classification number: C07D235/02 , C07C45/28 , C07D263/52 , C07D499/00 , Y02P20/55 , C07C49/67
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Patent Agency Ranking
公开(公告)号：US3340252A
公开(公告)日：1967-09-05
申请号：US35805064
申请日：1964-04-07
Applicant: AMERICAN HOME PROD
Inventor： ALBURN HARVEY E , GRANT NORMAN H
IPC: C07D499/00 , C07D499/64 , C07D499/68 , C07D499/74
CPC classification number: C07D499/00
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7.发明授权Potassium hydrogen sulfite addition product 6-l-(1-cytosinyl) and (1-uracilyl)-5-hydroxy-p-dioxane-2-dcarboxyaldehyde 失效亚硫酸氢钾加成产物6-1-（1-胞嘧啶基）和（1-尿嘧啶基）-5-羟基 - 对二恶烷-2-甲醛
公开(公告)号：US3317535A
公开(公告)日：1967-05-02
申请号：US43409165
申请日：1965-02-19
Applicant: AMERICAN HOME PROD
Inventor： ALBURN HARVEY E , WILLIAM DVONCH
IPC: C07F9/6561 , C07H19/20
CPC classification number: C07F9/65616 , C07H19/20
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8.发明授权Process for producing 6-(alpha-amino-acylamino-acylamino)-penicillanic acids 失效6-（α-氨基 - 酰氨基 - 酰氨基） - 青霉烷酸的制备方法
公开(公告)号：US3268513A
公开(公告)日：1966-08-23
申请号：US35357464
申请日：1964-03-20
Applicant: AMERICAN HOME PROD
Inventor： GRANT NORMAN H , ALBURN HARVEY E
IPC: C07D499/00 , C07D499/64
CPC classification number: C07D499/00
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公开(公告)号：US3252989A
公开(公告)日：1966-05-24
申请号：US25611563
申请日：1963-02-04
Applicant: AMERICAN HOME PROD
Inventor： FLETCHER III HORACE , ALBURN HARVEY E
IPC: C07D217/26 , C07D231/06 , C07D231/12 , C07D295/215 , C07D521/00
CPC classification number: C07D231/06 , C07D217/26 , C07D231/12 , C07D233/56 , C07D249/08 , C07D295/215
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公开(公告)号：US2727889A
公开(公告)日：1955-12-20
申请号：US22195151
申请日：1951-04-19
Applicant: AMERICAN HOME PROD
Inventor： ALBURN HARVEY E
CPC classification number: C08B37/0084
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