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公开(公告)号：US3655725A
公开(公告)日：1972-04-11
申请号：US3655725D
申请日：1970-10-16
Applicant: AMERICAN HOME PROD
Inventor： ALBURN HARVEY E , DVONCH WILLIAM
IPC: C07C101/36
CPC classification number: C07C2601/08
Abstract: THE PHENYL, MENTHYL, AND CHOLINE HALIDE ESTER OF 1AMINOCYCLOPENTANECARBOXYLIC ACID ARE PHARMACOLOGICALLY ACTIVE, SHOWING THE ABILITY TO BLOCK THE IMMUNE RESPONSE IN WARM-BLOODED ANIMALS.
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公开(公告)号：US3652609A
公开(公告)日：1972-03-28
申请号：US3652609D
申请日：1969-06-24
Applicant: AMERICAN HOME PROD
Inventor： ALBURN HARVEY E , DVONCH WILLIAM , GRANT NORMAN H
CPC classification number: A61K31/23
Abstract: PATTY ACID GLYCERIDES OF 2-PHENOXY-2-METHYLPROPIONIC ACIDS ARE PREPARED WHICH ARE USEFUL IN LOWERING BLOOD CHOLESTEROL AND TRIGLYCERIDE LEVELS IN WARM-BLOODED ANIMALS.
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公开(公告)号：US3577408A
公开(公告)日：1971-05-04
申请号：US3577408D
申请日：1968-10-15
Applicant: AMERICAN HOME PROD
Inventor： ALBURN HARVEY E , DVONCH WILLIAM , SALLAY STEPHAN
IPC: C07D499/00 , C07D499/76
CPC classification number: C07D499/00
Abstract: 6-(TETRAHYDRO - 2 - OXOFURAN - 3 - CARBOXAMIDO) PENICILLANIC ACIDS WHICH MAY BE SUBSTITUTED IN THE 3 AND 5 POSITIONS, OR THE OPENED RING FORMS OF THESE PENICILLINS ARE PRODUCED, HAVING ANTIBIOTIC ACTIVITY.
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公开(公告)号：US3573279A
公开(公告)日：1971-03-30
申请号：US3573279D
申请日：1967-01-25
Applicant: AMERICAN HOME PROD
Inventor： ALBURN HARVEY E , DVONCH WILLIAM
IPC: C07D499/00 , C07D499/74 , C07D99/16
CPC classification number: C07D499/00
Abstract: THE COMPOUNDS ARE CERTAIN 1-SUBSTITUTED CYCLOALKYL PENICILLINS HAVING ANTIBIOTIC ACTIVITY, AND ALSO INTERMEDIATES WHICH ARE USEFUL FOR PREPARING MIXED ANHYDRIDE COMPOUNDS SUITABLE FOR REACTING WITH 6-AMINOPENICILLANIC ACID FOR PRODUCING SAID PENICILLINS.
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公开(公告)号：US3886186A
公开(公告)日：1975-05-27
申请号：US39308773
申请日：1973-08-30
Applicant: AMERICAN HOME PROD
Inventor： DVONCH WILLIAM , ALBURN HARVEY E
IPC: C07D493/04 , C07D5/32
CPC classification number: C07D493/04
Abstract: The 2- and 5-nitrate esters of 1,4:3,6-dianhydro-D-glucitol are prepared by nitrating 1,4:3,6-dianhydro-D-glucitol. The mononitrates so produced are separated and converted by standard procedures to derivatives in which an alkyl, benzoyl, cycloalkyl, carbamoyl, sulfamoyl, or benzoyl radical is substituted on the hydroxyl group. The derivatives possess cardiovascular activity.
Abstract translation: 通过硝化1,4：3,6-二脱氢-D-葡萄糖醇制备1,4：3,6-二脱氢-D-葡萄糖醇的2-和5-硝酸酯。 如此制备的单硝酸酯通过标准方法分离并转化成衍生物，其中烷基，苯甲酰基，环烷基，氨基甲酰基，氨磺酰基或苯甲酰基被羟基取代。 衍生物具有心血管活性。
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Patent Agency Ranking
公开(公告)号：US3542776A
公开(公告)日：1970-11-24
申请号：US3542776D
申请日：1967-10-25
Applicant: AMERICAN HOME PROD
Inventor： DVONCH WILLIAM , ALBURN HARVEY E
IPC: C07D413/14 , C07D473/00 , C07D87/24
CPC classification number: C07D413/14 , C07D473/00
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公开(公告)号：US3522250A
公开(公告)日：1970-07-28
申请号：US3522250D
申请日：1968-10-15
Applicant: AMERICAN HOME PROD
Inventor： KERWIN RICHARD M , DVONCH WILLIAM , ALBURN HARVEY E
IPC: C07D501/18 , C07D501/26 , C07D99/24
CPC classification number: C07D501/18 , C07D501/26 , Y10S435/849
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8.发明授权7 - (1,4 - cyclohexadienylacylamido)cephalosporanic acids and related compounds 失效7-（1,4 - 环己基）乙酰氨基）碳氢化合物及相关化合物
公开(公告)号：US3704297A
公开(公告)日：1972-11-28
申请号：US3704297D
申请日：1971-03-05
Applicant: AMERICAN HOME PROD
Inventor： DVONCH WILLIAM , ALBURN HARVEY E
IPC: C07D501/20 , C07D99/24
CPC classification number: C07D501/20
Abstract: THIS INVENTION CONCERNS 7-(1,4-CYCLOHEXADIENYLACYLAMIDO) CEPHALOSPORANIC ACIDS, RELATES COMPOUNDS AND THE SALTS THEREOF WHICH HAVE POTENT ANTIBIOTIC ACTIVITY PARTICULARLY AGAINST PENICILLIN RESISTANT STAPHYLOCOCCI.
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9.发明授权7-(1-aminocycloalkylcarboxamido) cephalosporanic acids and related compounds 失效7-（1-氨基环戊氧基甲酰胺）碳二亚胺及其相关化合物
公开(公告)号：US3592812A
公开(公告)日：1971-07-13
申请号：US3592812D
申请日：1968-12-06
Applicant: AMERICAN HOME PROD
Inventor： ALBURN HARVEY E , DVONCH WILLIAM
IPC: C07D501/20 , C07D99/24
CPC classification number: C07D501/20
Abstract: NOVEL 7-(1-AMINOCYCLOALKYLCARBOXAMIDO) CEPHALOSPORANIC ACIDS, INCLUDING ALIPHATIC AND ARYL-CYCLOALKYL RING SUBSTITUTED CEPHALOSPORANIC ACIDS ARE PREPARED. THE COMPOUNDS HAVE USEFUL ANTIBIOTIC ACTIVITY.
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10.发明授权
公开(公告)号：US3576855A
公开(公告)日：1971-04-27
申请号：US3576855D
申请日：1969-02-07
Applicant: AMERICAN HOME PROD
Inventor： DVONCH WILLIAM , ALBURN HARVEY E
IPC: C07D499/00 , C07D499/68 , C07C101/44
CPC classification number: C07D499/00
Abstract: A COMPOUND, N-CHLOROFORMYL-N-PHENYLGLYCINE, USED AS AN INTERMEDIATE IN THE PREPARATION OF PENICILLINS.
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