公开(公告)号：US20150104452A1

公开(公告)日：2015-04-16

申请号：US14301305

申请日：2014-06-10

Applicant: AbbVie Inc.

Inventor： Tariq Ghayur ,  Edward B. Reilly ,  Andrew Phillips ,  Randy L. Bell ,  Yingchun Li ,  Hua Ying ,  Susan E. Morgan-Lappe ,  Gillian A. Kingsbury ,  Jieyi Wang ,  Suzanne M. Norvell ,  Junjian Liu

IPC: C07K16/46 ,  A61K45/06 ,  G01N33/68 ,  C07K16/28 ,  G01N33/74 ,  A61K39/395 ,  C07K16/22

CPC classification number: C07K16/468 ,  A61K39/39533 ,  A61K45/06 ,  A61K2039/505 ,  C07K16/22 ,  C07K16/28 ,  C07K16/2863 ,  C07K16/32 ,  C07K2317/31 ,  C07K2317/565 ,  C07K2317/64 ,  C07K2317/71 ,  C07K2317/73 ,  C07K2317/732 ,  C07K2317/734 ,  C07K2317/76 ,  C07K2317/92 ,  C07K2319/00 ,  G01N33/6872 ,  G01N33/74 ,  G01N2333/515 ,  G01N2333/705 ,  Y02A50/386 ,  Y02A50/41 ,  Y02A50/412 ,  Y02A50/58 ,  Y10S435/81

Abstract: The present invention relates to engineered multivalent and multispecific binding proteins, methods of making, and specifically to their uses in the prevention, diagnosis, and/or treatment of disease.