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1.发明申请METHOD TO MINIMIZE MOLECULAR WEIGHT DROP OF POLY(L-LACTIDE) STENT DURING PROCESSING 审中-公开在加工过程中最小化聚（L-LACTIDE）STENT分子量降低的方法公开(公告)号：US20150054202A1
公开(公告)日：2015-02-26
申请号：US14530151
申请日：2014-10-31
Applicant: Abbott Cardiovascular Systems Inc.
Inventor： Byron Lambert , Yunbing Wang , James Oberhauser
CPC classification number: B29C47/0076 , A61F2/82 , A61L31/041 , A61L31/06 , A61L31/143 , A61L31/148 , B29D23/20 , B29K2005/00 , B29L2023/20 , B29L2031/753 , C08J3/28 , C08J2367/04 , C08L67/04
Abstract: A method to reduce or minimize the reduction in molecular weight of a stent during processing is disclosed. The stent has a scaffolding including a polymer formulation comprising PLLA and polymandelide. The polymandelide reduces the molecular weight drop during processing, particularly during sterilization. The stent scaffolding can further include one or more additional stabilizing agents that additionally reduce the molecular weight drop during processing.
Abstract translation: 公开了减少或最小化处理期间支架分子量降低的方法。 支架具有包括PLLA和聚扁桃酸酯的聚合物制剂的脚手架。 聚对苯二甲酸丁二醇酯降低加工过程中的分子量下降，特别是在灭菌过程中。 支架支架还可包括一种或多种附加的稳定剂，其另外降低加工过程中的分子量下降。
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Patent Agency Ranking
公开(公告)号：US20150128527A1
公开(公告)日：2015-05-14
申请号：US14597119
申请日：2015-01-14
Applicant: Abbott Cardiovascular Systems Inc.
Inventor： Yunbing Wang , Derek Mortisen , Xiao Ma , Fuh-Wei Tang , Byron Lambert
IPC: B65B55/16
CPC classification number: A61F2/82 , A61F2/0095 , A61F2240/001 , A61L2/081 , A61L2/082 , A61L2/087 , B29C71/009 , B29C71/04 , B29C2035/0877 , B65B55/16
Abstract: Methods of stabilizing the molecular weight of polymer stents scaffolds after E-beam sterilization are disclosed. The molecular weight of the polymer of the irradiated scaffolds is stabilized through exposure to gas containing oxygen.
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3.发明授权Method to minimize molecular weight drop of poly(L-lactide) stent during processing 有权减少加工过程中聚（L-丙交酯）支架分子量下降的方法公开(公告)号：US09278470B2
公开(公告)日：2016-03-08
申请号：US14530151
申请日：2014-10-31
Applicant: Abbott Cardiovascular Systems Inc.
Inventor： Byron Lambert , Yunbing Wang , James Oberhauser
IPC: A61L31/06 , B29C47/00 , A61L31/04 , A61L31/14 , C08J3/28 , A61F2/82 , B29D23/20 , B29L23/20 , B29L31/00
CPC classification number: B29C47/0076 , A61F2/82 , A61L31/041 , A61L31/06 , A61L31/143 , A61L31/148 , B29D23/20 , B29K2005/00 , B29L2023/20 , B29L2031/753 , C08J3/28 , C08J2367/04 , C08L67/04
Abstract: A method to reduce or minimize the reduction in molecular weight of a stent during processing is disclosed. The stent has a scaffolding including a polymer formulation comprising PLLA and polymandelide. The polymandelide reduces the molecular weight drop during processing, particularly during sterilization. The stent scaffolding can further include one or more additional stabilizing agents that additionally reduce the molecular weight drop during processing.
Abstract translation: 公开了减少或最小化处理期间支架分子量降低的方法。 支架具有包括PLLA和聚扁桃酸酯的聚合物制剂的脚手架。 聚对苯二甲酸丁二醇酯降低加工过程中的分子量下降，特别是在灭菌过程中。 支架支架还可包括一种或多种附加的稳定剂，其另外降低加工过程中的分子量下降。
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4.发明申请公开(公告)号：US20150137428A1
公开(公告)日：2015-05-21
申请号：US14597144
申请日：2015-01-14
Applicant: Abbott Cardiovascular Systems Inc.
Inventor： Yunbing Wang , Kerek Mortisen , Xiao Ma , Fuh-Wei Tang , Byron Lambert
IPC: A61F2/82
CPC classification number: A61F2/82 , A61F2/0095 , A61F2240/001 , A61L2/081 , A61L2/082 , A61L2/087 , B29C71/009 , B29C71/04 , B29C2035/0877 , B65B55/16
Abstract: Methods of stabilizing the molecular weight of polymer stents scaffolds after E-beam sterilization are disclosed. The molecular weight of the polymer of the irradiated scaffolds is stabilized through exposure to gas containing oxygen.
Abstract translation: 公开了电子束灭菌后稳定聚合物支架支架分子量的方法。 照射的支架的聚合物的分子量通过暴露于含氧气体而稳定。
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5.发明申请STENTS INCLUDING POLY(L-LACTIDE) FORMULATIONS THAT MINIMIZE MOLECULAR WEIGHT DROP DURING PROCESSING 有权包括在加工过程中最小化分子量降低的聚（L-柠檬酸）配方的方法公开(公告)号：US20140012365A1
公开(公告)日：2014-01-09
申请号：US14022098
申请日：2013-09-09
Applicant: Abbott Cardiovascular Systems Inc.
Inventor： Byron Lambert , Yunbing Wang , James Oberhauser
CPC classification number: B29C47/0076 , A61F2/82 , A61L31/041 , A61L31/06 , A61L31/143 , A61L31/148 , B29D23/20 , B29K2005/00 , B29L2023/20 , B29L2031/753 , C08J3/28 , C08J2367/04 , C08L67/04
Abstract: A stent scaffolding including a polymer formulation comprising PLLA and polymandelide is disclosed. The polymandelide reduces the molecular weight drop during processing, particularly during sterilization. The stent scaffolding can further include one or more additional stabilizing agents that additionally reduce the molecular weight drop during processing.
Abstract translation: 公开了一种包括含有PLLA和聚扁桃酸酯的聚合物制剂的支架支架。 聚对苯二甲酸丁二醇酯降低加工过程中的分子量下降，特别是在灭菌过程中。 支架支架还可包括一种或多种附加的稳定剂，其另外降低加工过程中的分子量下降。
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6.发明授权Stents including poly(L-lactide) formulations that minimize molecular weight drop during processing 有权支架，包括聚（L-丙交酯）制剂，使加工过程中的分子量下降最小化公开(公告)号：US08882825B2
公开(公告)日：2014-11-11
申请号：US14022098
申请日：2013-09-09
Applicant: Abbott Cardiovascular Systems Inc.
Inventor： Byron Lambert , Yunbing Wang , James Oberhauser
CPC classification number: B29C47/0076 , A61F2/82 , A61L31/041 , A61L31/06 , A61L31/143 , A61L31/148 , B29D23/20 , B29K2005/00 , B29L2023/20 , B29L2031/753 , C08J3/28 , C08J2367/04 , C08L67/04
Abstract: A stent scaffolding including a polymer formulation comprising PLLA and polymandelide is disclosed. The polymandelide reduces the molecular weight drop during processing, particularly during sterilization. The stent scaffolding can further include one or more additional stabilizing agents that additionally reduce the molecular weight drop during processing.
Abstract translation: 公开了一种包括含有PLLA和聚扁桃酸酯的聚合物制剂的支架支架。 聚对苯二甲酸丁二醇酯降低加工过程中的分子量下降，特别是在灭菌过程中。 支架支架还可包括一种或多种附加的稳定剂，其另外降低加工过程中的分子量下降。
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