Abstract:
Flexible microconduits integral at a proximal end to a substrate and adapted for connection to a biological environment at the distal end are provided. Also provided are microsystems with at least one flexible microconduit integral at a proximal end to a substrate and with a distal end that is adapted for connection to a biological environment. The microconduits may be fluid conduits, electrical conduits, or electro-fluidic conduits that transmit both fluids and electrical signals. Methods for fabricating the microconduits and other structures integral with the substrate are also provided.
Abstract:
An apparatus and method for cell culture in microchambers that are formed on or adjacent to a substrate. The microchambers are connected by one or more fluid conduits, valves and reagent reservoirs, is disclosed.