专利检索 cpc:"F16K2099/0076" 第 1 页

1.

发明申请
LIQUID FEED DEVICE AND VALVE SYSTEM 审中-公开
标题翻译：液体进料装置和阀系统

公开(公告)号：US20150266025A1

公开(公告)日：2015-09-24

申请号：US14626205

申请日：2015-02-19

申请人： Kabushiki Kaisha Toshiba

发明人： Shinya TANIKAWA , Kenichi ARAME , Masayuki YUMOTO , Hirotaka UNNO , Tetsuya KUWABARA , Jun OKADA

IPC分类号： B01L3/00

CPC分类号： B01L3/567 , B01L3/0293 , B01L2300/123 , B01L2400/0655 , F16K99/0026 , F16K2099/0076

摘要： According to one embodiment, a liquid feed device includes a support substrate and an intermediate member. The intermediate member is provided on the support substrate. A valve and a flow channel of fluid are formed by the intermediate member. The valve communicates with the flow channel. The valve includes an outer edge portion and a gap. The gap is provided between the outer edge portion and the support substrate. The valve is capable of opening and closing the gap by the outer edge portion being pressed and released. A configuration of the outer edge portion when projected onto a plane perpendicular to a direction of the flow channel is a protruding configuration having a curved surface. The configuration of the outer edge portion is symmetric with respect to the direction of the flow channel.

摘要翻译： 根据一个实施例，液体供给装置包括支撑基板和中间部件。中间构件设置在支撑基板上。阀门和流体流道由中间构件形成。阀与流动通道连通。阀包括外边缘部分和间隙。间隙设置在外边缘部分和支撑基底之间。阀能够通过按压和释放的外边缘部分来打开和关闭间隙。当投影到与流动通道的方向垂直的平面上时，外边缘部分的构造是具有弯曲表面的突出构造。外边缘部分的结构相对于流动通道的方向是对称的。

2.

发明申请
Microfabricated Elastomeric Valve and Pump Systems 审中-公开
标题翻译：微型弹性阀和泵系统

公开(公告)号：US20150183633A1

公开(公告)日：2015-07-02

申请号：US14503252

申请日：2014-09-30

申请人： California Institute of Technology

发明人： Marc A. Unger , Hou-Pu Chou , Todd A. Thorsen , Axel Scherer , Stephen R. Quake

IPC分类号： B81B3/00

CPC分类号： B32B3/00 , B01J2219/00355 , B01J2219/00378 , B01J2219/00396 , B01J2219/00398 , B01J2219/00439 , B01J2219/005 , B01J2219/00527 , B01J2219/00605 , B01J2219/00612 , B01J2219/00659 , B01J2219/00707 , B01J2219/00722 , B01J2219/00725 , B01L3/502707 , B01L3/50273 , B01L3/502738 , B01L7/54 , B01L9/527 , B01L2200/025 , B01L2200/027 , B01L2200/0605 , B01L2200/10 , B01L2300/0681 , B01L2300/0861 , B01L2300/0887 , B01L2300/123 , B01L2300/14 , B01L2300/18 , B01L2400/046 , B01L2400/0481 , B01L2400/0655 , B01L2400/0688 , B32B2037/1081 , B81B3/0032 , B81B3/0051 , B81B2201/036 , B81B2201/054 , B81C1/00119 , B81C2201/019 , C12Q1/6874 , F04B43/043 , F15C5/00 , F16K99/0001 , F16K99/0015 , F16K99/0046 , F16K99/0051 , F16K99/0059 , F16K2099/0074 , F16K2099/0076 , F16K2099/0078 , F16K2099/008 , F16K2099/0094 , Y10T137/0491 , Y10T137/2224 , Y10T137/87716 , Y10T137/87804 , Y10T137/87812 , Y10T137/87893 , Y10T156/10 , Y10T156/1002 , Y10T156/1064 , Y10T428/24479 , Y10T428/2457 , Y10T428/24612 , Y10T428/24744 , C12Q2535/125

摘要： A method of fabricating an elastomeric structure, comprising: forming a first elastomeric layer on top of a first micromachined mold, the first micromachined mold having a first raised protrusion which forms a first recess extending along a bottom surface of the first elastomeric layer; forming a second elastomeric layer on top of a second micromachined mold, the second micromachined mold having a second raised protrusion which forms a second recess extending along a bottom surface of the second elastomeric layer; bonding the bottom surface of the second elastomeric layer onto a top surface of the first elastomeric layer such that a control channel forms in the second recess between the first and second elastomeric layers; and positioning the first elastomeric layer on top of a planar substrate such that a flow channel forms in the first recess between the first elastomeric layer and the planar substrate.

摘要翻译： 一种制造弹性体结构的方法，包括：在第一微加工模具的顶部上形成第一弹性体层，所述第一微加工模具具有形成沿所述第一弹性体层的底表面延伸的第一凹槽的第一凸起突起; 在第二微加工模具的顶部上形成第二弹性体层，所述第二微加工模具具有第二凸起突起，所述第二凸起突起形成沿所述第二弹性体层的底表面延伸的第二凹槽; 将第二弹性体层的底表面粘合到第一弹性体层的顶表面上，使得控制通道在第一和第二弹性体层之间的第二凹部中形成; 以及将第一弹性体层定位在平面基底的顶部上，使得流动通道在第一弹性体层和平面基底之间的第一凹部中形成。

3.

发明申请
MICROFABRICATED ELASTOMERIC VALVE AND PUMP SYSTEMS 审中-公开
标题翻译：微型弹药阀和泵系统

公开(公告)号：US20140322489A1

公开(公告)日：2014-10-30

申请号：US14218872

申请日：2014-03-18

申请人： California Institute of Technology

发明人： Marc A. Unger , Hou-Pu Chou , Todd A. Thorsen , Axel Scherer , Stephen R. Quake

IPC分类号： F16K13/00

CPC分类号： B29C51/00 , B01L3/502707 , B01L3/50273 , B01L3/502738 , B01L2300/0861 , B01L2300/0887 , B01L2300/123 , B01L2400/046 , B01L2400/0481 , B01L2400/0655 , B33Y80/00 , B81B5/00 , B81B2201/036 , B81B2201/054 , B81C1/00119 , B81C2201/019 , B81C2201/034 , C12Q1/6874 , F04B43/043 , F15C1/06 , F15C5/00 , F16K11/20 , F16K13/00 , F16K31/126 , F16K99/0001 , F16K99/0015 , F16K99/0046 , F16K99/0048 , F16K99/0051 , F16K99/0059 , F16K2099/0074 , F16K2099/0076 , F16K2099/0078 , F16K2099/008 , F16K2099/0094 , Y10T137/0491 , Y10T137/0497 , Y10T137/2224 , Y10T137/87249 , Y10T156/10 , Y10T428/24479 , Y10T428/24744 , C12Q2535/125

摘要： A method of fabricating an elastomeric structure, comprising: forming a first elastomeric layer on top of a first micromachined mold, the first micromachined mold having a first raised protrusion which forms a first recess extending along a bottom surface of the first elastomeric layer; forming a second elastomeric layer on top of a second micromachined mold, the second micromachined mold having a second raised protrusion which forms a second recess extending along a bottom surface of the second elastomeric layer; bonding the bottom surface of the second elastomeric layer onto a top surface of the first elastomeric layer such that a control channel forms in the second recess between the first and second elastomeric layers; and positioning the first elastomeric layer on top of a planar substrate such that a flow channel forms in the first recess between the first elastomeric layer and the planar substrate.

摘要翻译： 一种制造弹性体结构的方法，包括：在第一微加工模具的顶部上形成第一弹性体层，所述第一微加工模具具有形成沿所述第一弹性体层的底表面延伸的第一凹槽的第一凸起突起; 在第二微加工模具的顶部上形成第二弹性体层，所述第二微加工模具具有第二凸起突起，所述第二凸起突起形成沿所述第二弹性体层的底表面延伸的第二凹槽; 将第二弹性体层的底表面粘合到第一弹性体层的顶表面上，使得控制通道在第一和第二弹性体层之间的第二凹部中形成; 以及将第一弹性体层定位在平面基底的顶部上，使得流动通道在第一弹性体层和平面基底之间的第一凹部中形成。

4.

发明授权
Microfabricated elastomeric valve and pump systems 有权

公开(公告)号：US08846183B2

公开(公告)日：2014-09-30

申请号：US13278061

申请日：2011-10-20

申请人： Marc A. Unger , Hou-Pu Chou , Todd A. Thorsen , Axel Scherer , Stephen R. Quake

发明人： Marc A. Unger , Hou-Pu Chou , Todd A. Thorsen , Axel Scherer , Stephen R. Quake

IPC分类号： B32B3/00 , F16C1/06 , F16K1/00 , F16K7/00 , F16K31/145 , B29C65/00 , B29C45/14 , B01L3/00 , C12Q1/68 , B81C1/00 , F04B43/04 , F15C5/00 , B01L9/00 , F16K99/00 , B32B37/10 , B01L7/00

CPC分类号： B32B3/00 , B01J2219/00355 , B01J2219/00378 , B01J2219/00396 , B01J2219/00398 , B01J2219/00439 , B01J2219/005 , B01J2219/00527 , B01J2219/00605 , B01J2219/00612 , B01J2219/00659 , B01J2219/00707 , B01J2219/00722 , B01J2219/00725 , B01L3/502707 , B01L3/50273 , B01L3/502738 , B01L7/54 , B01L9/527 , B01L2200/025 , B01L2200/027 , B01L2200/0605 , B01L2200/10 , B01L2300/0681 , B01L2300/0861 , B01L2300/0887 , B01L2300/123 , B01L2300/14 , B01L2300/18 , B01L2400/046 , B01L2400/0481 , B01L2400/0655 , B01L2400/0688 , B32B2037/1081 , B81B3/0032 , B81B3/0051 , B81B2201/036 , B81B2201/054 , B81C1/00119 , B81C2201/019 , C12Q1/6874 , F04B43/043 , F15C5/00 , F16K99/0001 , F16K99/0015 , F16K99/0046 , F16K99/0051 , F16K99/0059 , F16K2099/0074 , F16K2099/0076 , F16K2099/0078 , F16K2099/008 , F16K2099/0094 , Y10T137/0491 , Y10T137/2224 , Y10T137/87716 , Y10T137/87804 , Y10T137/87812 , Y10T137/87893 , Y10T156/10 , Y10T156/1002 , Y10T156/1064 , Y10T428/24479 , Y10T428/2457 , Y10T428/24612 , Y10T428/24744 , C12Q2535/125

摘要： A method of fabricating an elastomeric structure, comprising: forming a first elastomeric layer on top of a first micromachined mold, the first micromachined mold having a first raised protrusion which forms a first recess extending along a bottom surface of the first elastomeric layer; forming a second elastomeric layer on top of a second micromachined mold, the second micromachined mold having a second raised protrusion which forms a second recess extending along a bottom surface of the second elastomeric layer; bonding the bottom surface of the second elastomeric layer onto a top surface of the first elastomeric layer such that a control channel forms in the second recess between the first and second elastomeric layers; and positioning the first elastomeric layer on top of a planar substrate such that a flow channel forms in the first recess between the first elastomeric layer and the planar substrate.

5.

发明申请
MICROFLUIDIC LARGE SCALE INTEGRATION 审中-公开
标题翻译：微型大规模集成

公开(公告)号：US20140065653A1

公开(公告)日：2014-03-06

申请号：US13679328

申请日：2012-11-16

申请人： California Institute of Technology

发明人： Sebastian J. Maerkl , Todd A. Thorsen , Xiaoyan Bao , Stephen R. Quake , Vincent Studer

IPC分类号： C12Q1/28

CPC分类号： C12Q1/28 , B01L3/5025 , B01L3/50273 , B01L3/502738 , B01L2300/0861 , B01L2300/0887 , B01L2400/0481 , B01L2400/0655 , B81B2201/0214 , B81B2201/054 , B81B2201/07 , B81C1/00119 , F15C5/00 , F16K11/20 , F16K99/0001 , F16K99/0015 , F16K99/0059 , F16K2099/0074 , F16K2099/0076 , F16K2099/0078 , F16K2099/008 , F16K2099/0084 , F16K2099/0094 , Y10T137/0318 , Y10T137/0329 , Y10T137/2224 , Y10T137/85938 , Y10T137/87249

摘要： High-density microfluidic chips contain plumbing networks with thousands of micromechanical valves and hundreds of individually addressable chambers. These fluidic devices are analogous to electronic integrated circuits fabricated using large scale integration (LSI). A component of these networks is the fluidic multiplexor, which is a combinatorial array of binary valve patterns that exponentially increases the processing power of a network by allowing complex fluid manipulations with a minimal number of inputs. These integrated microfluidic networks can be used to construct a variety of highly complex microfluidic devices, for example the microfluidic analog of a comparator array, and a microfluidic memory storage device resembling electronic random access memories.

摘要翻译： 高密度微流控芯片包含具有数千个微机械阀门和数百个单独可寻址腔室的管道网络。这些流体装置类似于使用大规模集成（LSI）制造的电子集成电路。这些网络的一个组件是流体多路复用器，它是二进制阀模式的组合阵列，通过允许使用最少数量的输入的复杂流体操纵来指数地增加网络的处理能力。这些集成的微流体网络可用于构建各种高度复杂的微流体装置，例如比较器阵列的微流体模拟装置和类似于电子随机存取存储器的微流体存储器存储装置。

6.

发明申请
CENTRIFUGAL FORCE-BASED MICROFLUIDIC DEVICE FOR NUCLEIC ACID EXTRACTION AND MICROFLUIDIC SYSTEM INCLUDING THE MICROFLUIDIC DEVICE 有权
标题翻译：用于核酸提取的基于离心力的微流体装置和包括微流体装置的微流体系统

公开(公告)号：US20120322132A1

公开(公告)日：2012-12-20

申请号：US13594293

申请日：2012-08-24

申请人： Yoon-kyoung CHO , Jeong-gun LEE , Beom-seok LEE , Jong-myeon PARK

发明人： Yoon-kyoung CHO , Jeong-gun LEE , Beom-seok LEE , Jong-myeon PARK

IPC分类号： C12M1/10 , G01N1/34 , C12N13/00

CPC分类号： B01L3/502738 , B01F13/0059 , B01F15/0201 , B01F15/0233 , B01L3/502753 , B01L3/502761 , B01L2300/0806 , B01L2300/0867 , B01L2300/087 , B01L2400/0409 , B01L2400/0677 , F16K99/0001 , F16K99/0017 , F16K99/0019 , F16K99/0032 , F16K99/004 , F16K2099/0076 , F16K2099/0084

摘要： A centrifugal force-based microfluidic device for nucleic acid extraction and a microfluidic system are provided. The microfluidic device includes a body of revolution; a microfluidic structure disposed in the body of revolution, the microfluidic structure including a plurality of chambers, channels connecting the chambers, and valves disposed in the channels to control fluid flow, the microfluidic structure transmitting the fluid using centrifugal force due to rotation of the body of revolution; and magnetic beads contained in one of the chambers which collect a target material from a biomaterial sample flowing into the chamber, wherein the microfluidic structure washes the magnetic beads which collect the target material, and separates nucleic acid by electromagnetic wave irradiation from an external energy source to the magnetic beads. The microfluidic system includes the microfluidic device; a rotation operating unit which rotates the body of revolution; and an external energy source which irradiates electromagnetic waves.

摘要翻译： 提供了用于核酸提取的离心力微流体装置和微流体系统。微流体装置包括一个革命体; 设置在旋转体内的微流体结构，所述微流体结构包括多个室，连接所述室的通道和设置在通道中的阀以控制流体流动，所述微流体结构由于所述体的旋转而使用离心力传递流体的革命以及包含在其中一个室中的磁珠，其从流入腔室的生物材料样品收集目标材料，其中微流体结构洗涤收集目标材料的磁珠，并通过来自外部能量源的电磁波照射分离核酸到磁珠。微流体系统包括微流体装置; 使旋转体旋转的旋转操作单元; 以及照射电磁波的外部能量源。

7.

发明申请
Thermal Microvalves 有权
标题翻译：热敏微孔

公开(公告)号：US20120077231A1

公开(公告)日：2012-03-29

申请号：US13311087

申请日：2011-12-05

申请人： Mark A. Burns , Brian N. Johnson , Michael Chen

发明人： Mark A. Burns , Brian N. Johnson , Michael Chen

IPC分类号： C12P19/34

CPC分类号： F16K99/0061 , B01J19/0093 , B01J2219/00783 , B01J2219/00822 , B01J2219/00828 , B01J2219/00831 , B01J2219/00837 , B01J2219/00853 , B01J2219/0086 , B01J2219/00873 , B01J2219/00889 , B01J2219/00891 , B01J2219/00957 , B01J2219/00961 , B01J2219/0097 , B01L3/502738 , B01L7/52 , B01L2300/0816 , B01L2300/1827 , B01L2400/0487 , B01L2400/0677 , F16K99/0001 , F16K99/0015 , F16K99/0034 , F16K2099/0071 , F16K2099/0074 , F16K2099/0076 , F16K2099/0084 , Y10T436/2575

摘要： The movement and mixing of microdroplets through microchannels is described employing silicon-based microscale devices, comprising microdroplet transport channels, reaction regions, electrophoresis modules, and radiation detectors. The discrete droplets are differentially heated and propelled through etched channels. Electronic components are fabricated on the same substrate material, allowing sensors and controlling circuitry to be incorporated in the same device.

摘要翻译： 使用硅微量元件描述了通过微通道的微滴的运动和混合，包括微滴输送通道，反应区域，电泳模块和辐射探测器。离散的液滴通过蚀刻通道进行差分加热和推进。电子元件制造在相同的基板材料上，允许将传感器和控制电路并入同一设备。

8.

发明授权
Method of increasing etchability of metals having chemical etching resistant microstructure 失效
标题翻译：具有耐化学蚀刻微观结构的金属的蚀刻性的提高方法

公开(公告)号：US08017028B2

公开(公告)日：2011-09-13

申请号：US12287772

申请日：2008-10-14

申请人： Mark Crockett , John W. Lane , Micahel DeChellis , Chris Melcer , Erica Porras , Aneesh Khullar , Balarabe N. Mohammed

发明人： Mark Crockett , John W. Lane , Micahel DeChellis , Chris Melcer , Erica Porras , Aneesh Khullar , Balarabe N. Mohammed

IPC分类号： C03C25/68

CPC分类号： F16K99/0001 , F16K27/003 , F16K99/0015 , F16K99/0028 , F16K99/0059 , F16K2099/0074 , F16K2099/0076

摘要： A space-conserving integrated fluid delivery system which is particularly useful for gas distribution in semiconductor processing equipment. The invention also includes an integrated fluid flow network architecture, which may include, in addition to a layered substrate containing fluid flow channels, various fluid handling and monitoring components. The layered substrate is diffusion bonded, and the various fluid handling and monitoring components may be partially integrated or fully integrated into the substrate, depending on design and material requirements.

摘要翻译： 提高具有抗化学蚀刻的微结构的金属的蚀刻性的方法（例如HASTELLOY C-22）。这是通过暂时去除提供对金属的耐腐蚀性的微结构来实现的。通过热处理金属去除微结构。化学蚀刻后，通过热处理将微结构恢复到其原始的耐腐蚀性。