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公开(公告)号:US20090214660A1
公开(公告)日:2009-08-27
申请号:US12090981
申请日:2006-10-24
申请人: Alfred Vasconcellos , Dwaine Emerich , Chris Thanos , Briannan Bintz , Marilyn Sandra Geaney , Stephen John Martin Skinner , Paul Lip Jin Tan
发明人: Alfred Vasconcellos , Dwaine Emerich , Chris Thanos , Briannan Bintz , Marilyn Sandra Geaney , Stephen John Martin Skinner , Paul Lip Jin Tan
CPC分类号: A61K9/5036 , A61K38/47 , C08B37/0084 , C12N5/0012 , C12N2533/32 , C12N2533/74
摘要: The present invention is directed to a composition comprising high mannuronic acid-containing alginate and a polycation having a polydispersity index of less than 1.5. The composition is particularly useful for making biocompatible microcapsules containing living cells for allo- or xeno-transplantation. Such microcapsules have enhanced durability and can maintain their structural and functional integrity over long periods of time compared to prior art alginate microcapsules.
摘要翻译: 本发明涉及包含高甘露糖醛酸的藻酸盐和多分散指数小于1.5的聚阳离子的组合物。 该组合物特别可用于制备含有活细胞用于异种或异种移植的生物相容性微胶囊。 与现有技术的藻酸盐微胶囊相比,这种微胶囊具有增强的耐久性并且可以在长时间内保持其结构和功能完整性。
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公开(公告)号:US20110177025A1
公开(公告)日:2011-07-21
申请号:US13054428
申请日:2009-07-15
申请人: Christopher Thanos , Briannan Bintz
发明人: Christopher Thanos , Briannan Bintz
IPC分类号: A61K38/20 , A61K38/00 , A61K38/18 , A61K38/30 , A61K38/16 , A61K38/29 , A61K38/14 , A61K38/31 , A61K35/12 , C12N5/07 , A61K8/64 , A61P17/02 , A61Q19/00
CPC分类号: A61K35/30 , A61K8/11 , A61K8/64 , A61K8/733 , A61K8/981 , A61K9/0014 , A61K9/0019 , A61K9/1647 , A61K9/19 , A61K9/5036 , A61K31/203 , A61K38/18 , A61K38/19 , A61K38/31 , A61K45/06 , A61K2800/412 , A61Q7/00 , A61Q19/00 , A61K2300/00
摘要: The invention relates to methods and compositions for improving wound healing and in particular for preventing scar formation and thus loss of function that can occur in injured tissues during the natural wound healing process. Particularly, although by no means exclusively, the invention relates to the healing of chronic wounds such as diabetic ulcers.
摘要翻译: 本发明涉及用于改善伤口愈合的方法和组合物,特别是用于防止在自然伤口愈合过程中损伤的组织中可能发生的瘢痕形成和因此丧失功能。 特别地,尽管绝不是专门,本发明涉及慢性伤口如糖尿病性溃疡的愈合。
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