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1.发明授权公开(公告)号：US11033576B2
公开(公告)日：2021-06-15
申请号：US16929837
申请日：2020-07-15
Applicant: AMORPHICAL LTD.
Inventor： Yosef Ben , Yigal Dov Blum
Abstract: The present invention provides compositions comprising amorphous calcium carbonate (ACC), suitable to being administered by inhalation, and methods for their use in treating ACC-responsive diseases and conditions. Further provided are ACC compositions suitable for buccal or sublingual administration.
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公开(公告)号：US12115184B2
公开(公告)日：2024-10-15
申请号：US17343471
申请日：2021-06-09
Applicant: AMORPHICAL LTD.
Inventor： Yosef Ben , Yigal Dov Blum , Hagay Moshe , Ben Ashkenazi
CPC classification number: A61K33/10 , A61K9/0019 , A61K9/0056 , A61K9/0073 , A61K9/10 , A61K9/143 , A61K47/24 , A61P31/00 , A61P35/00
Abstract: The present invention provides solid compositions of amorphous calcium carbonate (ACC) and a polyphosphate, bisphosphonate or pharmaceutical salts thereof as a stabilizer. Said stabilizers stabilizes the ACC and prevent crystallization to crystalline calcium carbonate (CCC) for a long period of time, even in an aqueous suspension. The invention further provides pharmaceutical composition comprising the solid ACC compositions as well their use in treating of certain diseases and conditions.
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公开(公告)号：US20220313729A1
公开(公告)日：2022-10-06
申请号：US17624612
申请日：2020-07-23
Applicant: AMORPHICAL LTD
Inventor： Yossi Ben , Yigal Dov Blum
Abstract: The present invention provides methods for enhancing and improving athletic performances of both professional and non-professional athletes by administering compositions comprising stabilized amorphous calcium carbonate. The enhanced athletic performances result among others from enhanced muscle performances, enhanced recovery and endurance.
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4.发明申请公开(公告)号：US20210260103A1
公开(公告)日：2021-08-26
申请号：US17319292
申请日：2021-05-13
Applicant: AMORPHICAL LTD.
Inventor： Yosef Ben , Yigal Dov Blum
Abstract: The present invention provides compositions comprising amorphous calcium carbonate (ACC), suitable to being administered by inhalation, and methods for their use in treating ACC-responsive diseases and conditions. Kits for preparing suspension compositions of the present invention are provided as well.
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5.发明申请公开(公告)号：US20200345763A1
公开(公告)日：2020-11-05
申请号：US16929837
申请日：2020-07-15
Applicant: AMORPHICAL LTD.
Inventor： Yosef Ben , Yigal Dov Blum
Abstract: The present invention provides compositions comprising amorphous calcium carbonate (ACC), suitable to being administered by inhalation, and methods for their use in treating ACC-responsive diseases and conditions. Further provided are ACC compositions suitable for buccal or sublingual administration.
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Patent Agency Ranking
公开(公告)号：US20250017957A1
公开(公告)日：2025-01-16
申请号：US18901396
申请日：2024-09-30
Applicant: AMORPHICAL LTD.
Inventor： Yosef Ben , Yigal Dov Blum , Hagay Moshe , Ben Ashkenazi
Abstract: The present invention provides solid compositions of amorphous calcium carbonate (ACC) and a polyphosphate, bisphosphonate or pharmaceutical salts thereof as a stabilizer. Said stabilizers stabilizes the ACC and prevent crystallization to crystalline calcium carbonate (CCC) for a long period of time, even in an aqueous suspension. The invention further provides pharmaceutical composition comprising the solid ACC compositions as well their use in treating of certain diseases and conditions.
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公开(公告)号：US20230365935A1
公开(公告)日：2023-11-16
申请号：US18200938
申请日：2023-05-23
Applicant: Amorphical Ltd.
Inventor： Yosef Ben , Yigal Dov Blum , Sara NEUMAN , Orit ECKER
CPC classification number: C12N5/0658 , A61P21/00 , C12N2500/14
Abstract: Stabilized amorphous calcium carbonate (ACC) as a supplement of cell culture media and the cell culture medium supplements comprising stabilized ACC are provided. In particular the stabilized ACC is useful for enhancing the growth of cell and tissue cultures, gametes and embryos in vitro and particularly in microgravity.
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公开(公告)号：US20210308178A1
公开(公告)日：2021-10-07
申请号：US17343471
申请日：2021-06-09
Applicant: AMORPHICAL LTD.
Inventor： Yosef Ben , Yigal Dov Blum , Hagay Moshe , Ben Ashkenazi
Abstract: The present invention provides solid compositions of amorphous calcium carbonate (ACC) and a polyphosphate, bisphosphonate or pharmaceutical salts thereof as a stabilizer. Said stabilizers stabilizes the ACC and prevent crystallization to crystalline calcium carbonate (CCC) for a long period of time, even in an aqueous suspension. The invention further provides pharmaceutical composition comprising the solid ACC compositions as well their use in treating of certain diseases and conditions.
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9.发明申请公开(公告)号：US20180153930A1
公开(公告)日：2018-06-07
申请号：US15578829
申请日：2016-06-02
Applicant: AMORPHICAL LTD.
Inventor： Yosef Ben , Yigal Dov Blum
Abstract: The present invention provides compositions comprising amorphous calcium carbonate (ACC), suitable to being administered by inhalation, and methods for their use in treating ACC-responsive diseases and conditions. Further provided are ACC compositions suitable for buccal or sublingual administration.
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10.发明授权公开(公告)号：US12121538B2
公开(公告)日：2024-10-22
申请号：US17319292
申请日：2021-05-13
Applicant: AMORPHICAL LTD.
Inventor： Yosef Ben , Yigal Dov Blum
CPC classification number: A61K33/10 , A61K9/0019 , A61K9/0056 , A61K9/0073 , A61K9/10 , A61K9/143 , A61K47/24 , A61P31/00 , A61P35/00
Abstract: The present invention provides compositions comprising amorphous calcium carbonate (ACC), suitable to being administered by inhalation, and methods for their use in treating ACC-responsive diseases and conditions. Kits for preparing suspension compositions of the present invention are provided as well.
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