公开(公告)号：US20130096495A1

公开(公告)日：2013-04-18

申请号：US13515903

申请日：2010-11-30

申请人： Anders Holmqvist ,  Magnus Gustafsson ,  Stefan Lööf ,  Jochen Ratjen

发明人： Anders Holmqvist ,  Magnus Gustafsson ,  Stefan Lööf ,  Jochen Ratjen

IPC分类号： A61M5/315

CPC分类号： A61M5/31566 ,  A61M5/14244 ,  A61M5/1454 ,  A61M5/14566 ,  A61M5/2033 ,  A61M5/2066 ,  A61M5/2448 ,  A61M5/3129 ,  A61M5/31511 ,  A61M5/31593 ,  A61M5/31596 ,  A61M2005/2073 ,  A61M2005/31518

摘要： A medicament delivery device includes a housing with a circle-segment-shaped compartment for a drive unit that moves at least one stopper in a medicament container and that includes a support wheel and central hub on which first and second parallel disks are fixedly attached and interconnected by an abutment cross-wall; spherical members between the abutment wall and adjacent the stopper; a clock spring within the hub with an outer end connected to the hub and an inner end connected to a one-direction-rotatable tubular hub coaxially arranged around a shaft fixedly attached to a housing part; and an activation member connected to the first disk by a hold-and-release mechanism. When the activation member is not depressed, the wheel and spring are held in a tensioned static state, and when the activation member is depressed, the spring and wheel are released and the spherical members are forced against the stopper.

摘要翻译： 药物输送装置包括具有用于驱动单元的圆形扇形隔室的壳体，该驱动单元将至少一个止动件移动到药物容器中，并且包括支撑轮和中心毂，第一和第二平行盘固定在其上并互连 通过邻接跨墙; 邻接壁与邻接塞之间的球形构件; 轮毂内的时钟弹簧，其外端连接到轮毂，内端连接到单向可旋转的管状轮毂，其同轴地布置在固定地连接到壳体部分的轴周围; 以及通过保持 - 释放机构连接到第一盘的激活构件。 当激活构件未被压下时，轮和弹簧被保持在张紧的静止状态，并且当致动构件被压下时，弹簧和轮被释放，并且球形构件被迫靠在止动件上。

公开(公告)号：US09320855B2

公开(公告)日：2016-04-26

申请号：US13983562

申请日：2012-01-31

申请人： Anders Holmqvist ,  Stefan Lööf

发明人： Anders Holmqvist ,  Stefan Lööf

IPC分类号： A61M5/315 ,  A61M5/20 ,  A61M5/24

CPC分类号： A61M5/31596 ,  A61M5/20 ,  A61M5/2033 ,  A61M5/2066 ,  A61M5/2448 ,  A61M5/31505 ,  A61M5/31565 ,  A61M2005/2026 ,  A61M2005/2073 ,  A61M2005/2451

摘要： A medicament delivery device for a reconstituted medicament, comprising a proximal housing part (12; 12″; 12′″), a distal housing part (10; 10″; 10′″), a medicament delivery drive unit and actuation means, wherein the medicament delivery drive unit is mounted in said distal housing part and wherein the actuation means further include an activation member (74; 101; 201) which is displaceable between an inactive position wherein the actuator is prevented from engaging the medicament delivery drive unit and an active position wherein the actuator is able to engage the medicament delivery drive, whereby the actuator is capable of interacting with said medicament delivery drive unit to perform a delivery of the reconstituted medicament only in the active position of the activation member and in the second position of the medicament delivery drive unit.

摘要翻译： 一种用于复原药物的药物输送装置，包括近端壳体部分（12; 12“; 12”），远端壳体部分（10; 10“; 10”），药物输送驱动单元和致动装置，其中 所述药物输送驱动单元安装在所述远侧壳体部分中，并且其中所述致动装置还包括致动构件（74; 101; 201），其可在非活动位置之间移动，其中所述致动器被阻止接合所述药物输送驱动单元和 活动位置，其中所述致动器能够接合所述药物输送驱动器，由此致动器能够与所述药物输送驱动单元相互作用，以仅在所述激活构件的主动位置执行所述重构药剂的输送，并且在所述第二位置 药物输送驱动单元。

公开(公告)号：US20140371670A1

公开(公告)日：2014-12-18

申请号：US13983562

申请日：2012-01-31

申请人： Anders Holmqvist ,  Stefan Lööf

发明人： Anders Holmqvist ,  Stefan Lööf

IPC分类号： A61M5/315 ,  A61M5/20

CPC分类号： A61M5/31596 ,  A61M5/20 ,  A61M5/2033 ,  A61M5/2066 ,  A61M5/2448 ,  A61M5/31505 ,  A61M5/31565 ,  A61M2005/2026 ,  A61M2005/2073 ,  A61M2005/2451

摘要： A medicament delivery device for a reconstituted medicament, comprising a proximal housing part (12; 12″; 12′″), a distal housing part (10; 10″; 10′″), a medicament delivery drive unit and actuation means, wherein the medicament delivery drive unit is mounted in said distal housing part and wherein the actuation means further include an activation member (74; 101; 201) which is displaceable between an inactive position wherein the actuator is prevented from engaging the medicament delivery drive unit and an active position wherein the actuator is able to engage the medicament delivery drive, whereby the actuator is capable of interacting with said medicament delivery drive unit to perform a delivery of the reconstituted medicament only in the active position of the activation member and in the second position of the medicament delivery drive unit.

摘要翻译： 一种用于复原药物的药物输送装置，包括近端壳体部分（12; 12“; 12”），远端壳体部分（10; 10“; 10”），药物输送驱动单元和致动装置，其中 所述药物输送驱动单元安装在所述远侧壳体部分中，并且其中所述致动装置还包括致动构件（74; 101; 201），其可在非活动位置之间移动，其中所述致动器被阻止接合所述药物输送驱动单元和 活动位置，其中所述致动器能够接合所述药物输送驱动器，由此致动器能够与所述药物输送驱动单元相互作用，以仅在所述激活构件的主动位置执行所述重构药剂的输送，并且在所述第二位置 药物输送驱动单元。

公开(公告)号：US09737668B2

公开(公告)日：2017-08-22

申请号：US14009942

申请日：2012-03-30

申请人： Anders Holmqvist

发明人： Anders Holmqvist

IPC分类号： A61M5/32 ,  A61M5/20

CPC分类号： A61M5/3202 ,  A61M5/2033 ,  A61M5/3257 ,  A61M2005/208

摘要： Medicament delivery device comprising a movable guard (10) being movable between a proximal and a distal position and a locking mechanism (15) having a lever (16), the lever (16) restricting movement of an actuation locking member (24) until the movable guard is positioned in a distal position and the lever (16) restricting movement of the guard (10) in a proximal position after actuation of the device.

公开(公告)号：US09345844B2

公开(公告)日：2016-05-24

申请号：US13885901

申请日：2011-11-18

申请人： Anders Holmqvist

发明人： Anders Holmqvist

IPC分类号： A61M5/315 ,  A61M5/32 ,  A61M5/19 ,  A61M5/24 ,  A61M5/28

CPC分类号： A61M5/3293 ,  A61M5/19 ,  A61M5/2448 ,  A61M5/284 ,  A61M5/31596 ,  A61M5/3243 ,  A61M5/326

摘要： Medicament delivery device comprising a housing (10) and container holder (12) accommodating a multi-chamber medicament container wherein said housing and said medicament container holder are interactively connected to and movable relative each other; a mixing guard mechanism interactively connected to the body for driving the medicament container holder within the housing achieving a reconstitution, wherein the mixing guard mechanism comprises a guard member (34), a force member (52), a guard member locking means (24, 42) whereby, when the reconstitution is achieved, the medicament container holder and the guard member are movable in relation to said housing from a pre-mix position to a mixed position wherein said medicament container holder has been displaced distally in relation to said housing, at which mixed position said guard member locking means is activated, whereby said guard member is forced in the proximal direction by said force member for covering the delivery member (22).

摘要翻译： 药物输送装置包括容纳多室药物容器的壳体（10）和容器保持器（12），其中所述壳体和所述药物容器保持器相互交互地连接并相对于彼此移动; 混合保护机构，其与所述主体交互地连接以驱动所述壳体内的所述药物容器保持器，从而实现重构，其中所述混合保护机构包括防护构件（34），力构件（52），防护构件锁定装置 42），由此，当实现重构时，药物容器保持器和防护构件可相对于所述壳体从预混合位置移动到混合位置，其中所述药物容器保持器相对于所述壳体向远侧移位， 在所述混合位置，所述保护构件锁定装置被启动，由此所述防护构件通过所述力构件在近端方向被迫动以覆盖所述传送构件（22）。

公开(公告)号：US08876785B2

公开(公告)日：2014-11-04

申请号：US13139294

申请日：2009-11-26

申请人： Anders Holmqvist

发明人： Anders Holmqvist

IPC分类号： A61M5/00 ,  A61M5/31 ,  A61M15/00 ,  A61M5/24 ,  A61M5/34 ,  A61M11/00

CPC分类号： A61M5/3134 ,  A61M5/24 ,  A61M5/347 ,  A61M5/348 ,  A61M11/00 ,  A61M15/00 ,  A61M2005/2407

摘要： The present invention relates to a delivery member attachment device (10) comprising a neck (12) having an inner space intended to accommodate a connection part of a medicament container, which neck (12) is intended to receive a delivery member (30) for creating a passage between the medicament container via the connection part and through the delivery member, that said neck (12) is arranged with threads (14) arranged to engage with corresponding threads (34) of an attachment part (32 of said delivery member (30), and wherein said neck (12) further is arranged with a number of slits (16) providing a number of tongues (18) between said slits, and wherein said tongues (18) are arranged to flex inwards, when a delivery member (30) is to be attached, to allow an axial pushing of said attachment part (32) onto, and in engagement with, said neck (12).

摘要翻译： 本发明涉及一种包括颈部（12）的输送部件附接装置（10），所述颈部（12）具有用于容纳药物容器的连接部分的内部空间，该颈部（12）旨在接纳用于 在所述药物容器之间经由所述连接部分和通过所述递送构件形成通道，所述颈部（12）布置有螺纹（14），所述螺纹（14）布置成与所述输送构件（32）的附接部分（32）的相应螺纹（34） 30），并且其中所述颈部（12）还布置有多个狭缝（16），所述狭缝（16）在所述狭缝之间提供多个舌片（18），并且其中所述舌片（18）布置成向内弯曲， （30），以允许所述附接部分（32）轴向推动到所述颈部（12）上并与所述颈部（12）接合。

公开(公告)号：US20140163473A1

公开(公告)日：2014-06-12

申请号：US14118328

申请日：2012-05-07

申请人： Anders Holmqvist ,  Maria Hedin

发明人： Anders Holmqvist ,  Maria Hedin

IPC分类号： A61M5/315

CPC分类号： A61M5/31535 ,  A61M5/31571 ,  A61M5/31595

摘要： Device for medicament delivery with syringe-like usability having a locking mechanism. A device for medicament delivery with syringe-like usability with at least one grip (30), at least one plunger rod (20) being substantially rotationally fixed relatively to the grip, and at least one locking mechanism (17) configured to substantially inhibit movement of the plunger rod in a longitudinal direction of the device for dose delivery when being in at least one locking position. The locking mechanism comprises at least one rotatable part (40) that is substantially fixed in a longitudinal direction, that is rotatable relatively to the grip, and that interacts with the plunger rod. The device comprises at least one indicator drum (60).

摘要翻译： 用于药物输送的装置，其具有具有锁定机构的注射器状可用性。 一种用于具有至少一个手柄（30）的注射器状可用性的药物输送装置，至少一个柱塞杆（20）相对于手柄基本上旋转地固定，以及至少一个锁定机构（17），其构造成基本上抑制运动 在处于至少一个锁定位置时，用于剂量递送的装置的纵向方向上的柱塞杆。 锁定机构包括至少一个可沿纵向方向基本上固定的可旋转部分（40），其可相对于把手旋转并且与柱塞杆相互作用。 该装置包括至少一个指示鼓（60）。

公开(公告)号：US20130041322A1

公开(公告)日：2013-02-14

申请号：US13642524

申请日：2011-04-14

申请人： Anders Holmqvist

发明人： Anders Holmqvist

IPC分类号： A61M5/315 ,  A61M5/31

CPC分类号： A61M5/31525 ,  A61M5/20 ,  A61M5/31535 ,  A61M5/31548 ,  A61M5/3155 ,  A61M5/31558 ,  A61M5/31583 ,  A61M2005/202

摘要： A medicament delivery device has proximal and distal housing parts connected along a longitudinal axis, the proximal part for accommodating a medicament container. A drive member inside the distal part has a first circumferential set of interacting devices. A longitudinal plunger rod is rotationally locked through a central passage of the distal part, acts on a stopper inside the container, and is connected to the plunger rod. A turnable dose setting member coaxially arranged around the drive member is rotatably connected to the distal part. A torsion spring is connected to the dose setting member and to a hub of the drive member. The hub, spring, dose setting member, and drive member are coaxial transversally. The drive nut has second interacting devices on its outer surface. When the drive member is rotated by the spring, the drive nut rotates, whereby the plunger rod moves proximally for expelling a dose of medicament.

摘要翻译： 药物输送装置具有沿着纵向轴线连接的近端和远端壳体部分，所述近端部分用于容纳药物容器。 远侧部分内部的驱动构件具有第一周向组合的相互作用装置。 纵向柱塞杆通过远端部分的中心通道旋转地锁定，作用在容器内的止动件上，并连接到柱塞杆。 同轴地布置在驱动构件周围的可转动剂量设定构件可旋转地连接到远端部分。 扭力弹簧连接到剂量设定构件和驱动构件的毂。 毂，弹簧，剂量设定构件和驱动构件是横向同轴的。 驱动螺母在其外表面上具有第二相互作用装置。 当驱动构件被弹簧旋转时，驱动螺母旋转，由此柱塞杆向近侧移动以排出一定剂量的药物。

公开(公告)号：US20110288493A1

公开(公告)日：2011-11-24

申请号：US13139294

申请日：2009-11-26

申请人： Anders Holmqvist

发明人： Anders Holmqvist

IPC分类号： A61M5/34

CPC分类号： A61M5/3134 ,  A61M5/24 ,  A61M5/347 ,  A61M5/348 ,  A61M11/00 ,  A61M15/00 ,  A61M2005/2407

摘要： The present invention relates to a delivery member attachment device (10) comprising a neck (12) having an inner space intended to accommodate a connection part of a medicament container, which neck (12) is intended to receive a delivery member (30) for creating a passage between the medicament container via the connection part and through the delivery member, that said neck (12) is arranged with threads (14) arranged to engage with corresponding threads (34) of an attachment part (32 of said delivery member (30), and wherein said neck (12) further is arranged with a number of slits (16) providing a number of tongues (18) between said slits, and wherein said tongues (18) are arranged to flex inwards, when a delivery member (30) is to be attached, to allow an axial pushing of said attachment part (32) onto, and in engagement with, said neck (12).

摘要翻译： 本发明涉及一种包括颈部（12）的输送部件附接装置（10），所述颈部（12）具有用于容纳药物容器的连接部分的内部空间，该颈部（12）旨在接纳用于 在所述药物容器之间经由所述连接部分和通过所述递送构件形成通道，所述颈部（12）布置有螺纹（14），所述螺纹（14）布置成与所述输送构件（32）的附接部分（32）的相应螺纹（34） 30），并且其中所述颈部（12）还布置有多个狭缝（16），所述狭缝（16）在所述狭缝之间提供多个舌片（18），并且其中所述舌片（18）布置成向内弯曲， （30），以允许所述附接部分（32）轴向推动到所述颈部（12）上并与所述颈部（12）接合。

公开(公告)号：US09011375B2

公开(公告)日：2015-04-21

申请号：US13819529

申请日：2011-08-23

申请人： Anders Holmqvist ,  Sebastian Karlsson

发明人： Anders Holmqvist ,  Sebastian Karlsson

IPC分类号： A61M5/20 ,  A61M5/315 ,  A61M5/24 ,  A61M5/28

CPC分类号： A61M5/31515 ,  A61M5/2033 ,  A61M5/2066 ,  A61M5/24 ,  A61M5/28 ,  A61M5/31501 ,  A61M5/31511

摘要： A medicament delivery device includes a housing; a drive force mechanism slidable in the housing's distal part; a member connected to the drive force mechanism for holding it in a loaded state and axially movable in relation to the distal part a predetermined distance by the housing's proximal part when the parts are moved toward each other; and an actuation member to be biased in relation to the distal part from a non-operating position partially protruding from the distal part to an operating position confined within the distal part. The actuation member can release the drive force mechanism from its loaded state, and is resiliently connected to the distal part such that it is always recoiled after being biased regardless of whether the actuation mechanism is released. The drive force mechanism is released only after the holding member moves and the actuation member is biased from non-operating to operating position.

摘要翻译： 药物输送装置包括壳体; 驱动力机构，其可在所述壳体的远端部分中滑动; 连接到所述驱动力机构的构件，用于将所述驱动力机构保持在加载状态，并且当所述部件朝向彼此移动时，通过所述壳体的近端部分相对于所述远端部分轴向移动预定距离; 以及致动构件，其相对于所述远端部分从从所述远端部分突出到限制在所述远端部分内的操作位置的非操作位置偏置。 致动构件可以将驱动力机构从其装载状态释放，并且弹性地连接到远端部分，使得其在被施加偏压之后总是被反冲，而不管驱动机构是否被释放。 驱动力机构仅在保持构件移动并且致动构件从不操作到偏置到操作位置之后被释放。