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1.发明公开公开(公告)号：US20230211290A1
公开(公告)日：2023-07-06
申请号：US18008749
申请日：2021-06-10
Applicant: BASF SE
Inventor： Emiel Jan KAPPERT , Jacek MALISZ , Frederike CARSTENSEN , Anne-Catrin HAILER
CPC classification number: B01D61/146 , B01D61/22 , B01D2311/10 , B01D2311/18 , B01D2311/2626
Abstract: The present invention relates to a method for separating biomass from a solution comprising bi-omass and at least one aroma compound. comprising providing the solution comprising bio-mass and aroma compounds. lowering the pH value of the solution below 7 by adding at least one acid to the solution comprising biomass and the at least one aroma compound. adding an adsorbing agent to the solution comprising biomass and aroma compounds. and carrying out first membrane filtration so as to separate the biomass from the solution comprising the at least one aroma compound.
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公开(公告)号：US20230042456A1
公开(公告)日：2023-02-09
申请号：US17786864
申请日：2020-12-16
Applicant: BASF SE
Inventor： Hartwig SCHROEDER , Anne-Catrin HAILER , Birgit HOFF , Oskar ZELDER , Peter OEDMAN , Georg Benjamin WANDREY , Christian DIETZSCH , Mukesh KUMAR , Dominik SATORY , Matthew David BLANKSCHIEN , Jens Klaus PLASSMEIER
Abstract: Increasing space-time-yield, carbon-conversion-efficiency and carbon substrate flexibility in the production of fine chemicals The inventors of the current invention have found a surprising positive effect of increased cAMP levels and/or manipulating the PTS system on the space-time-yield, carbon-conversion-efficiency and carbon substrate flexibility of fine chemical production of a host organism. This was achieved by de-regulating adenylate cyclase cyaa by deleting the C-terminal regulatory region leading to increased cAMP levels or deleting the Crr protein activity (carbohydrate repression resistance) which regulates the carbohydrate utilization system. Both lead to increased 2-fucosyllactoe and 6-sialyllactose production (human milk oligosaccharides) and increase carbohydrate usage.
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